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View Structure Prediction Details

Protein: GCN5_ARATH
Organism: Arabidopsis thaliana
Length: 568 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GCN5_ARATH.

Description E-value Query
Range
Subject
Range
gi|50733046 - gi|50733046|ref|XP_426001.1| PREDICTED: similar to PCAF [Gallus gallus]
488.0 [0..47] [559..452]

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Predicted Domain #1
Region A:
Residues: [1-213]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSHSSHLNA ANRSRSSQTP SPSHSASASV TSSLHKRKLA ATTAANAAAS EDHAPPSSSF  60
   61 PPSSFSADTR DGALTSNDEL ESISARGADT DSDPDESEDI VVDDDEDEFA PEQDQDSSIR 120
  121 TFTAARLDSS SGVNGSSRNT KLKTESSTVK LESSDGGKDG GSSVVGTGVS GTVGGSSISG 180
  181 LVPKDESVKV LAENFQTSGA YIAREEALKR EEQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [214-371]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AGRLKFVCYS NDSIDEHMMC LIGLKNIFAR QLPNMPKEYI VRLLMDRKHK SVMVLRGNLV  60
   61 VGGITYRPYH SQKFGEIAFC AITADEQVKG YGTRLMNHLK QHARDVDGLT HFLTYADNNA 120
  121 VGYFVKQGFT KEIYLEKDVW HGFIKDYDGG LLMECKID

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 75.221849
Match: 1yghA
Description: Catalytic domain of GCN5 histone acetyltransferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
N-acetyltransferase activity 10.330867741687 bayes_pls_golite062009
histone acetyltransferase activity 10.2385402730839 bayes_pls_golite062009
lysine N-acetyltransferase activity 10.2385402730839 bayes_pls_golite062009
N-acyltransferase activity 10.2097972775096 bayes_pls_golite062009
acetyltransferase activity 9.5414870492393 bayes_pls_golite062009
acyltransferase activity 8.84144467104026 bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups 8.80032457938662 bayes_pls_golite062009
transferase activity, transferring acyl groups 8.58458341779614 bayes_pls_golite062009
7.30820970670781 bayes_pls_golite062009
3.86052919290021 bayes_pls_golite062009
H3 histone acetyltransferase activity 3.27931674770011 bayes_pls_golite062009
transferase activity 2.87429355361226 bayes_pls_golite062009
catalytic activity 1.97933499002461 bayes_pls_golite062009
binding 1.07749536895426 bayes_pls_golite062009
glycylpeptide N-tetradecanoyltransferase activity 0.774009286200155 bayes_pls_golite062009
myristoyltransferase activity 0.774009286200155 bayes_pls_golite062009
histone binding 0.582104626133107 bayes_pls_golite062009
nucleic acid binding 0.522132859536345 bayes_pls_golite062009
protein binding 0.283213965640071 bayes_pls_golite062009
transcription regulator activity 0.0766125702622449 bayes_pls_golite062009
transcription coactivator activity 0.0504023697864295 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [372-568]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PKLPYTDLSS MIRQQRKAID ERIRELSNCQ NVYPKIEFLK NEAGIPRKII KVEEIRGLRE  60
   61 AGWTPDQWGH TRFKLFNGSA DMVTNQKQLN ALMRALLKTM QDHADAWPFK EPVDSRDVPD 120
  121 YYDIIKDPID LKVIAKRVES EQYYVTLDMF VADARRMFNN CRTYNSPDTI YYKCATRLET 180
  181 HFHSKVQAGL QSGAKSQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.39794
Match: 1eqfA
Description: TAFII250 double bromodomain module
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle