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Protein Overview: SCAR2_ARATH

General Information:
Name(s) found: SCAR2_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|75111022|sp|Q5XPJ9.1|SCAR2_ARATH RecName: Full=Protein SCAR2; Short=AtSCAR2; AltName: Full=Protein WAVE4; AltName: Full=Protein DISTORTED 3; AltName: Full=Protein IRREGULAR TRICHOME BRANCH 1 [NCBI NR]
  • gi|57240100|gb|AAW49260.1| DISTORTED3/SCAR2 [Arabidopsis thaliana] [NCBI NR]
  • gi|53801278|gb|AAU93849.1| SCAR2 [Arabidopsis thaliana] [NCBI NR]
  • gi|30687512|ref|NP_181378.2| SCAR2 (SCAR HOMOLOG 2) [Arabidopsis thaliana] [NCBI NR]
  • Protein SCAR2 OS=Arabidopsis thaliana GN=SCAR2 PE=1 SV=1 [Swiss-Prot]
  • SCAR2 [Arabidopsis thaliana]gi|30687512|ref|NP_181378.2| expressed protein [Arabidopsis thaliana] [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Protein SCAR2 [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: SCAR2, DIS3, WAVE4, ITB1 | ITB1 (IRREGULAR TRICHOME BRANCH1) | chr2:16102628-16107929 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • SCAR2 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • Protein SCAR2 (AtSCAR2) (Protein WAVE4) (Protein DISTORTED3) (Protein IRREGULAR TRICHOME BRANCH1) [nr-271106-contam.fasta]
  • DISTORTED3/SCAR2 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • ITB1 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: ITB1, SCAR2, DIS3, WAVE4, ATSCAR2 | SCAR homolog 2 | chr2:16095550-16100851 FORWARD LENGTH=1399 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 1399 amino acids

    Gene Ontology:
    Cellular Component: SCAR complex [ISS][TAS]
    cytoplasm [IDA]
    plasma membrane [IDA]
    Biological Process: cell-cell adhesion [IMP]
    actin nucleation [TAS]
    trichome branching [IMP]
    trichome morphogenesis [IMP][TAS]
    actin cytoskeleton organization [IMP]
    positive regulation of actin nucleation [IMP][ISS]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPLTRYQSRN EYGLADPDLY QAADKDDPEA LLEGVAMAGL VGILRQLGDL AEFAAEMFHD  60
   61 LHEEVMATAS RSHGLMARVQ QLEAEFPSIE KALLCQTDHS PFFSNKGVEW HPNLQLEQSV 120
  121 VTSGDLPRCV MDSYEECRGP PRLFLLDKFD ISGAGACLKR YTDPSFVRLE TSSYEESWDD 180
  181 IQREKKSQKA KRRASQWRNG GTPENALSSH AKLHELFLEE HLEAHHSDPA RVVKLKTRKL 240
  241 DGCSLISKSG ESYMEKFVQT RVDSKISYEI ITQNPGLLTW NMDSARDVVT DIPEISMVGA 300
  301 MDKSHGGSRA EVSFPSEQEN VANVNMNGGF IEKDIETVPE STYNEVRGTT ITQDSQTVLN 360
  361 GKPGFFQQRS YSEDLTSEAD NYVDAPATME SETETDDECR PKSRSDTLKD GNHHIYSDAV 420
  421 EERMEDPPQF SFSHSNGNTP VSENGRSSFG KKSTSYSYSD TASISIDDQS DGEKLSGCLP 480
  481 STSSFKSELV DSMSHVTPEA NKVSHDLNVQ ESVSSSNVDG QTSLSSNGTC SSPRPVSQND 540
  541 QSCSLTVQSL ASEVVETSPE LVRLDLMKGG NDGRKVDPFD SSKSCASFDA KNSDLPSETS 600
  601 SISSTSEGSR CDSTIEKNCM VASNLVNSGT SPQAFVDSQT GKQLPIADTD FETNSIVACS 660
  661 EVLANSGSDP EERDGRCLTG KLVPCSAGVG MEVSPDTPSK VCGPSSADGI HLKDTLDDET 720
  721 DCVSVTNVVV DVDSKNSVAD VGSQSSVADI DSQSSVAEIS DEHSCAFGNT ADVSVSESHE 780
  781 DTLENGMSVP SDFNSGVEKL AGDASPTCSK CDDHISHEGF HDLSGLDNAT TDIVPNVELD 840
  841 VSDNDNDTSS GGVNHAVSLS STRGKGSLPW ISTNTYQSSS DAGEIFHDTV VESDGTLLED 900
  901 NNPESEIKMH KSPLEVSSEG LSTEPDNKDV ESIESTSPKP SLDQRNRDTE TKSPGESILD 960
  961 DNCIDSTQVY NLNLLESEAI DQAVREQTSY ASHEVADEEL LQSNVFRGLE FEPQSAGLEF1020
 1021 APQSAGIELN RPKQELNLDP TFPSFGFIPE TIPPNPEDMP PLPPMQWLIG KVPHSFPTFM1080
 1081 GESVETSSSA LSAAPPIGSS LNVQIGSPPS ELSVSLGSDE SERLPGGFVH NASEKPLQSS1140
 1141 IQFPTMSTDL NSQYDSSELP TIPYQECIED FGSEENNLLA DHAAQNHELV YSQASSLQLP1200
 1201 QVKHEDFKDD ADVHESQSSS DDHHCPETKS LTPTQSTKVE DKGHSVPDAS NAETAESSNT1260
 1261 SVQKINPVSV GDAMWPVSCF SVAPTLDTYK TEVVPTVRLP RPRSPLVDAV AAHDRRKMKK1320
 1321 VSEMVHPPIK SKQDDKDSLL AQIRNKSVNL KPAVTTRPSI QTGPRTDLRV AAILEKANTI1380
 1381 RMAMAGSDED EDSDSWSDS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..297] deduced N/A No confident structure predictions are available.
    2 View Details [298..443] deduced N/A No confident structure predictions are available.
    3 View Details [444..510] deduced N/A No confident structure predictions are available.
    4 View Details [511..565] deduced N/A No confident structure predictions are available.
    5 View Details [566..784] deduced N/A No confident structure predictions are available.
    6 View Details [785..910] deduced N/A No confident structure predictions are available.
    7 View Details [911..1058] deduced N/A No confident structure predictions are available.
    8 View Details [1059..1321] MSA 2.365996 View MSA. No confident structure predictions are available.
    9 View Details [1322..1399] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle