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Protein Overview: PMS1_YEAST

General Information:
Name(s) found: PMS1_YEAST [Swiss-Prot]
Description(s) found:
Found 2 descriptions.
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  • DNA mismatch repair protein PMS1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PMS1 PE=1 SV=3 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 873 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTQIHQINDI DVHRITSGQV ITDLTTAVKE LVDNSIDANA NQIEIIFKDY GLESIECSDN  60
   61 GDGIDPSNYE FLALKHYTSK IAKFQDVAKV QTLGFRGEAL SSLCGIAKLS VITTTSPPKA 120
  121 DKLEYDMVGH ITSKTTTSRN KGTTVLVSQL FHNLPVRQKE FSKTFKRQFT KCLTVIQGYA 180
  181 IINAAIKFSV WNITPKGKKN LILSTMRNSS MRKNISSVFG AGGMRGLEEV DLVLDLNPFK 240
  241 NRMLGKYTDD PDFLDLDYKI RVKGYISQNS FGCGRNSKDR QFIYVNKRPV EYSTLLKCCN 300
  301 EVYKTFNNVQ FPAVFLNLEL PMSLIDVNVT PDKRVILLHN ERAVIDIFKT TLSDYYNRQE 360
  361 LALPKRMCSQ SEQQAQKRLK TEVFDDRSTT HESDNENYHT ARSESNQSNH AHFNSTTGVI 420
  421 DKSNGTELTS VMDGNYTNVT DVIGSECEVS VDSSVVLDEG NSSTPTKKLP SIKTDSQNLS 480
  481 DLNLNNFSNP EFQNITSPDK ARSLEKVVEE PVYFDIDGEK FQEKAVLSQA DGLVFVDNEC 540
  541 HEHTNDCCHQ ERRGSTDTEQ DDEADSIYAE IEPVEINVRT PLKNSRKSIS KDNYRSLSDG 600
  601 LTHRKFEDEI LEYNLSTKNF KEISKNGKQM SSIISKRKSE AQENIIKNKD ELEDFEQGEK 660
  661 YLTLTVSKND FKKMEVVGQF NLGFIIVTRK VDNKYDLFIV DQHASDEKYN FETLQAVTVF 720
  721 KSQKLIIPQP VELSVIDELV VLDNLPVFEK NGFKLKIDEE EEFGSRVKLL SLPTSKQTLF 780
  781 DLGDFNELIH LIKEDGGLRR DNIRCSKIRS MFAMRACRSS IMIGKPLNKK TMTRVVHNLS 840
  841 ELDKPWNCPH GRPTMRHLME LRDWSSFSKD YEI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..403] PSI-BLAST 68.39794 DNA mismatch repair protein PMS2
    2 View Details [404..590] MSA 4.434992 View MSA. No confident structure predictions are available.
    3 View Details [591..733] MSA 1.139986 View MSA. No confident structure predictions are available.
    4 View Details [734..826] deduced N/A No confident structure predictions are available.
    5 View Details [827..873] MSA 3.062993 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • mismatched DNA binding
    		•  8.69038541722775 bayes_pls_golite062009
  • DNA insertion or deletion binding
    		•  7.03361327424191 bayes_pls_golite062009
    		• 6.04882684441736 bayes_pls_golite062009
  • guanine/thymine mispair binding
    		•  5.8954303695758 bayes_pls_golite062009
  • mismatch repair complex binding
    		•  5.63566878749852 bayes_pls_golite062009
  • single base insertion or deletion binding
    		•  5.36719395837475 bayes_pls_golite062009
  • dinucleotide insertion or deletion binding
    		•  4.91072939712457 bayes_pls_golite062009
  • loop DNA binding
    		•  4.26052361441101 bayes_pls_golite062009
  • DNA topoisomerase (ATP-hydrolyzing) activity
    		•  2.66323092512867 bayes_pls_golite062009
  • DNA topoisomerase activity
    		•  2.35776058207527 bayes_pls_golite062009
  • protein kinase activity
    		•  2.13536672517084 bayes_pls_golite062009
  • catalytic activity
    		•  2.10890475146569 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.77725015786603 bayes_pls_golite062009
  • kinase activity
    		•  1.68443268281997 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.64025200399404 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.37978051130887 bayes_pls_golite062009
  • DNA binding
    		•  1.31521246060081 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  1.22640171545155 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.22084067619837 bayes_pls_golite062009
  • transferase activity
    		•  1.09369139087478 bayes_pls_golite062009
  • exonuclease activity
    		•  1.02947145936572 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.996368427522977 bayes_pls_golite062009
  • signal transducer activity
    		•  0.996368427522977 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.91402301750067 bayes_pls_golite062009
  • binding
    		•  0.908938377164829 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  0.86218415868631 bayes_pls_golite062009
  • MutSalpha complex binding
    		•  0.8423412194292 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  0.839521076707668 bayes_pls_golite062009
  • ribonuclease activity
    		•  0.75307991342421 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.71251019785001 bayes_pls_golite062009
  • nuclease activity
    		•  0.69721312877891 bayes_pls_golite062009
  • 3'-5'-exoribonuclease activity
    		•  0.48105441429954 bayes_pls_golite062009
  • 3'-5' exonuclease activity
    		•  0.477960254167 bayes_pls_golite062009
  • structural molecule activity
    		•  0.41673693977319 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  0.36703663415044 bayes_pls_golite062009
  • exoribonuclease activity
    		•  0.350394896843651 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle