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Protein Overview: EG10203

General Information:
Name(s) found: dacC / EG10203 [EcoGene]
Description(s) found:
Found 4 descriptions.
SHOW ALL
  • D-alanyl-D-alanine carboxypeptidase; penicillin-binding protein 6a / D-alanine D-alanine carboxypeptidase PBP6; penicillin-binding protein 6 [EcoGene]
    • Organism: Escherichia coli str. K-12 substr. MG1655
    Length: 400 amino acids

    Gene Ontology:
    Cellular Component: integral to plasma membrane [IDALink to PubMed article]
    extrinsic to membrane [IEA]
    Biological Process: regulation of cell shape [IEA][IGILink to PubMed articleLink to PubMed articleLink to PubMed article]
    response to drug [IMPLink to PubMed article]
    peptidoglycan biosynthetic process [IDALink to PubMed articleLink to PubMed article][IEA]
    proteolysis [IEA]
    Molecular Function: carboxypeptidase activity [IDALink to PubMed articleLink to PubMed article][IEA]
    serine-type D-Ala-D-Ala carboxypeptidase activity [IEA]
    penicillin binding [IDALink to PubMed articleLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTQYSSLLRG LAAGSAFLFL FAPTAFAAEQ TVEAPSVDAR AWILMDYASG KVLAEGNADE  60
   61 KLDPASLTKI MTSYVVGQAL KADKIKLTDM VTVGKDAWAT GNPALRGSSV MFLKPGDQVS 120
  121 VADLNKGVII QSGNDACIAL ADYVAGSQES FIGLMNGYAK KLGLTNTTFQ TVHGLDAPGQ 180
  181 FSTARDMALL GKALIHDVPE EYAIHKEKEF TFNKIRQPNR NRLLWSSNLN VDGMKTGTTA 240
  241 GAGYNLVASA TQGDMRLISV VLGAKTDRIR FNESEKLLTW GFRFFETVTP IKPDATFVTQ 300
  301 RVWFGDKSEV NLGAGEAGSV TIPRGQLKNL KASYTLTEPQ LTAPLKKGQV VGTIDFQLNG 360
  361 KSIEQRPLIV MENVEEGGFF GRVWDFVMMK FHQWFGSWFS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..400] PSI-BLAST 107.0 Penicillin-binding protein 5, C-terminal domain; Penicillin-binding protein 5, N-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • drug binding
    		•  3.43867028493374 bayes_pls_golite062009
  • peptidase activity
    		•  3.14503902416546 bayes_pls_golite062009
  • serine-type D-Ala-D-Ala carboxypeptidase activity
    		•  3.12650314537616 bayes_pls_golite062009
  • penicillin binding
    		•  2.89507018520983 bayes_pls_golite062009
  • hydrolase activity
    		•  2.80171403488139 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  2.78480589579188 bayes_pls_golite062009
  • serine-type carboxypeptidase activity
    		•  2.70174066798582 bayes_pls_golite062009
  • serine-type exopeptidase activity
    		•  2.69091897402517 bayes_pls_golite062009
  • carboxypeptidase activity
    		•  1.96547160092829 bayes_pls_golite062009
  • catalytic activity
    		•  1.85492008367309 bayes_pls_golite062009
  • serine hydrolase activity
    		•  1.69122379434116 bayes_pls_golite062009
  • serine-type peptidase activity
    		•  1.6885532900392 bayes_pls_golite062009
  • exopeptidase activity
    		•  1.24775184094433 bayes_pls_golite062009
  • binding
    		•  1.11566650386305 bayes_pls_golite062009
  • protein binding
    		•  0.0666688846338231 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle