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Protein Overview: EG10580

General Information:
Name(s) found: mepA / EG10580 [EcoGene]
Description(s) found:
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  • murein DD-endopeptidase / Murein DD-endopeptidase, penicillin-insensitive [EcoGene]
  • murein DD-endopeptidase [Escherichia coli K12] [nr-271106-contam.fasta]
  • penicillin-insensitive murein endopeptidase [Escherichia coli K12] [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • murein DD-endopeptidase [Escherichia coli str. K-12 substr. MG1655] [Ecoli-contam-Dam1-Mind-COMA-MBP-110.fasta]
    • Organism: Escherichia coli str. K-12 substr. MG1655
    Length: 274 amino acids

    Gene Ontology:
    Cellular Component: outer membrane-bounded periplasmic space [IEA]
    periplasmic space [IEA]
    Biological Process: peptidoglycan metabolic process [IDALink to PubMed articleLink to PubMed article][IEA][IMPLink to PubMed articleLink to PubMed article]
    proteolysis [IEA]
    Molecular Function: zinc ion binding [IEA]
    metal ion binding [IEA]
    serine-type endopeptidase activity [IEA]
    endopeptidase activity [IMPLink to PubMed articleLink to PubMed article]
    peptidase activity [IDALink to PubMed article][IMPLink to PubMed article]
    metalloendopeptidase activity [IEA]
    metallopeptidase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNKTAIALLA LLASSASLAA TPWQKITQPV PGSAQSIGSF SNGCIVGADT LPIQSEHYQV  60
   61 MRTDQRRYFG HPDLVMFIQR LSSQVSNLGM GTVLIGDMGM PAGGRFNGGH ASHQTGLDVD 120
  121 IFLQLPKTRW TSAQLLRPQA LDLVSRDGKH VVSTLWKPEI FSLIKLAAQD KDVTRIFVNP 180
  181 AIKQQLCLDA GTDRDWLRKV RPWFQHRAHM HVRLRCPADS LECEDQPLPP SGDGCGAELQ 240
  241 SWFEPPKPGT TKPEKKTPPP LPPSCQALLD EHVI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..274] PSI-BLAST 109.0 MEPA, inactive form without ZN in P21

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  0.579809417316389 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle