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Protein Overview: EG12612

General Information:
Name(s) found: degQ / EG12612 [EcoGene]
Description(s) found:
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  • serine endoprotease, periplasmic / Periplasmic serine endoprotease; multicopy suppressor of prc and degP [EcoGene]
  • ORF_o455 [Escherichia coli] [nr-271106-contam.fasta]
  • serine endoprotease, periplasmic [Escherichia coli K12] [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • serine endoprotease, periplasmic [Escherichia coli str. K-12 substr. MG1655] [Ecoli-contam-Dam1-Mind-COMA-MBP-110.fasta]
    • Organism: Escherichia coli str. K-12 substr. MG1655
    Length: 455 amino acids

    Gene Ontology:
    Cellular Component: periplasmic space [IEA]
    Biological Process: proteolysis [IEA]
    Molecular Function: protein binding [IEA]
    catalytic activity [IEA]
    serine-type peptidase activity [IEA]
    serine-type endopeptidase activity [IEA]
    peptidase activity [IEA]
    hydrolase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKQTQLLSA LALSVGLTLS ASFQAVASIP GQVADQAPLP SLAPMLEKVL PAVVSVRVEG  60
   61 TASQGQKIPE EFKKFFGDDL PDQPAQPFEG LGSGVIINAS KGYVLTNNHV INQAQKISIQ 120
  121 LNDGREFDAK LIGSDDQSDI ALLQIQNPSK LTQIAIADSD KLRVGDFAVA VGNPFGLGQT 180
  181 ATSGIVSALG RSGLNLEGLE NFIQTDASIN RGNSGGALLN LNGELIGINT AILAPGGGSV 240
  241 GIGFAIPSNM ARTLAQQLID FGEIKRGLLG IKGTEMSADI AKAFNLDVQR GAFVSEVLPG 300
  301 SGSAKAGVKA GDIITSLNGK PLNSFAELRS RIATTEPGTK VKLGLLRNGK PLEVEVTLDT 360
  361 STSSSASAEM ITPALEGATL SDGQLKDGGK GIKIDEVVKG SPAAQAGLQK DDVIIGVNRD 420
  421 RVNSIAEMRK VLAAKPAIIA LQIVRGNESI YLLMR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..455] PSI-BLAST 91.30103 Protease Do (DegP, HtrA), C-terminal domains; Protease Do (DegP, HtrA), catalytic domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein binding
    		•  2.10639523340529 bayes_pls_golite062009
  • hydrolase activity
    		•  1.95262287761731 bayes_pls_golite062009
  • binding
    		•  1.92577219161709 bayes_pls_golite062009
  • peptidase activity
    		•  0.892956033345508 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  0.644798716305534 bayes_pls_golite062009
  • endopeptidase activity
    		•  0.323781287331288 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle