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Protein Overview: EG10396

General Information:
Name(s) found: glpF / EG10396 [EcoGene]
Description(s) found:
Found 5 descriptions.
SHOW ALL
  • glycerol facilitator / Aquaglyceroporin; glycerol facilitator [EcoGene]
    • Organism: Escherichia coli str. K-12 substr. MG1655
    Length: 281 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEA]
    integral to membrane [IEA]
    plasma membrane [IEA]
    Biological Process: transmembrane transport [IEA]
    glycerol transport [IMPLink to PubMed article]
    Molecular Function: magnesium ion binding [IEA]
    glycerol channel activity [IDALink to PubMed article]
    metal ion binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQTSTLKGQ CIAEFLGTGL LIFFGVGCVA ALKVAGASFG QWEISVIWGL GVAMAIYLTA  60
   61 GVSGAHLNPA VTIALWLFAC FDKRKVIPFI VSQVAGAFCA AALVYGLYYN LFFDFEQTHH 120
  121 IVRGSVESVD LAGTFSTYPN PHINFVQAFA VEMVITAILM GLILALTDDG NGVPRGPLAP 180
  181 LLIGLLIAVI GASMGPLTGF AMNPARDFGP KVFAWLAGWG NVAFTGGRDI PYFLVPLFGP 240
  241 IVGAIVGAFA YRKLIGRHLP CDICVVEEKE TTTPSEQKAS L

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..281] PSI-BLAST 64.30103 Glycerol uptake facilitator protein GlpF

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • water transmembrane transporter activity
    		•  10.3414560257964 bayes_pls_golite062009
  • water channel activity
    		•  10.2169080705067 bayes_pls_golite062009
  • amide transmembrane transporter activity
    		•  8.22334514934522 bayes_pls_golite062009
  • urea channel activity
    		•  8.22334514934522 bayes_pls_golite062009
  • urea transmembrane transporter activity
    		•  8.22334514934522 bayes_pls_golite062009
  • glycerol transmembrane transporter activity
    		•  6.84984722645819 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  6.65010837320829 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  6.65010837320829 bayes_pls_golite062009
  • transporter activity
    		•  5.23077472964938 bayes_pls_golite062009
  • pyrimidine transmembrane transporter activity
    		•  5.22583580934587 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  5.0695479460357 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  5.06520190871345 bayes_pls_golite062009
  • channel activity
    		•  5.06054430984045 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  5.06054430984045 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  4.83314424546299 bayes_pls_golite062009
  • glycerol channel activity
    		•  4.65460547189577 bayes_pls_golite062009
  • nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity
    		•  2.87423888562609 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  2.82456291801633 bayes_pls_golite062009
  • organic acid transmembrane transporter activity
    		•  1.57078059027065 bayes_pls_golite062009
  • carboxylic acid transmembrane transporter activity
    		•  1.57017437613762 bayes_pls_golite062009
  • nucleobase transmembrane transporter activity
    		•  1.34339324336864 bayes_pls_golite062009
  • purine transmembrane transporter activity
    		•  1.34339324336864 bayes_pls_golite062009
  • binding
    		•  1.29002883661034 bayes_pls_golite062009
  • amine transmembrane transporter activity
    		•  1.16825682067665 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.516648340085278 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.315342449421593 bayes_pls_golite062009
  • protein binding
    		•  0.279304481542405 bayes_pls_golite062009
  • structural molecule activity
    		•  0.180281371901848 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.141210715822635 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  0.0368961725897963 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle