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Protein Overview: CNIF1_ARATH

General Information:
Name(s) found: CNIF1_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|75249321|sp|Q93WX6.1|NFS2_ARATH RecName: Full=Cysteine desulfurase 2, chloroplastic; AltName: Full=Selenocysteine lyase; AltName: Full=Protein AtCpNifS; AltName: Full=NIFS-like protein; AltName: Full=Plastid sufS-like protein; Flags: Precursor [NCBI NR]
  • gi|27085243|gb|AAL79956.1| cysteine desulfurase [Arabidopsis thaliana] [NCBI NR]
  • gi|23506185|gb|AAN31104.1| At1g08490/T27G7_14 [Arabidopsis thaliana] [NCBI NR]
  • gi|22329419|ref|NP_172325.2| CPNIFS (CHLOROPLASTIC NIFS-LIKE CYSTEINE DESULFURASE); cysteine desulfurase/ selenocysteine lyase/ transaminase [Arabidopsis thaliana] [NCBI NR]
  • gi|20453112|gb|AAM19798.1| At1g08490/T27G7_14 [Arabidopsis thaliana] [NCBI NR]
  • gi|16152176|gb|AAL14994.1|AF419347_1 NIFS-like protein CpNifsp precursor [Arabidopsis thaliana] [NCBI NR]
  • Cysteine desulfurase 2, chloroplastic OS=Arabidopsis thaliana GN=NFS2 PE=1 SV=1 [Swiss-Prot]
  • Cysteine desulfurase 1, chloroplastic OS=Arabidopsis thaliana GN=NFS2 PE=1 SV=1 [Swiss-Prot]
  • At1g08490/T27G7_14 [Arabidopsis thaliana]gi|20453112|gb|AAM19798.1| At1g08490/T27G7_14 [Arabidopsis thaliana]gi|27085243|gb|AAL79956.1| cysteine desulfurase [Arabidopsis thaliana]gi|16152176|gb|AAL14994.1| NIFS-like protein CpNifsp precursor [Arabidops [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Cysteine desulfurase [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: ATSUFS, SUFS, ATCPNIFS, ATNFS2, CPNIFS | ATCPNIFS/ATNFS2/ATSUFS/CPNIFS/SUFS (CHLOROPLASTIC NIFS-LIKE CYSTEINE DESULFURASE); cysteine desulfurase/ selenocysteine lyase/ transaminase | chr1:2685983-2688550 REVERSE [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • At1g08490/T27G7_14 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • Cysteine desulfurase 2, chloroplast precursor (Selenocysteine lyase) (Protein AtCpNifS) (NIFS-like protein) (Plastid sufS-like protein) [nr-271106-contam.fasta]
  • cysteine desulfurase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • NIFS-like protein CpNifsp precursor [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • transaminase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: ATSUFS, SUFS, ATCPNIFS, ATNFS2, CPNIFS | chloroplastic NIFS-like cysteine desulfurase | chr1:2685980-2688547 REVERSE LENGTH=463 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 463 amino acids

    Gene Ontology:
    Cellular Component: chloroplast [IDA]
    Biological Process: selenium metabolic process [IDA]
    sulfur metabolic process [IDA]
    iron incorporation into metallo-sulfur cluster [IDA]
    response to selenium ion [IMP]
    Molecular Function: cysteine desulfurase activity [IDA]
    transaminase activity [ISS]
    selenocysteine lyase activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEGVAMKLPS FPNAISIGHR SFSRVRCSSS LSVCSAAAAS SATISTDSES VSLGHRVRKD  60
   61 FRILHQEVNG SKLVYLDSAA TSQKPAAVLD ALQNYYEFYN SNVHRGIHYL SAKATDEFEL 120
  121 ARKKVARFIN ASDSREIVFT RNATEAINLV AYSWGLSNLK PGDEVILTVA EHHSCIVPWQ 180
  181 IVSQKTGAVL KFVTLNEDEV PDINKLRELI SPKTKLVAVH HVSNVLASSL PIEEIVVWAH 240
  241 DVGAKVLVDA CQSVPHMVVD VQKLNADFLV ASSHKMCGPT GIGFLYGKSD LLHSMPPFLG 300
  301 GGEMISDVFL DHSTYAEPPS RFEAGTPAIG EAIALGAAVD YLSGIGMPKI HEYEVEIGKY 360
  361 LYEKLSSLPD VRIYGPRPSE SVHRGALCSF NVEGLHPTDL ATFLDQQHGV AIRSGHHCAQ 420
  421 PLHRYLGVNA SARASLYFYN TKDDVDAFIV ALADTVSFFN SFK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..463] PSI-BLAST 107.0 Structure of slr0077/SufS, the Essential Cysteine Desulfurase from Synechocystis PCC 6803

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor
    		•  3.40354781002256 bayes_pls_golite062009
  • glycine dehydrogenase (decarboxylating) activity
    		•  3.40354781002256 bayes_pls_golite062009
  • transferase activity
    		•  2.59075614411581 bayes_pls_golite062009
  • catalytic activity
    		•  2.29878871754893 bayes_pls_golite062009
  • L-aspartate:2-oxoglutarate aminotransferase activity
    		•  1.62166853560902 bayes_pls_golite062009
  • cysteine desulfurase activity
    		•  1.30923778688541 bayes_pls_golite062009
  • transferase activity, transferring nitrogenous groups
    		•  1.28316822767388 bayes_pls_golite062009
  • transaminase activity
    		•  1.24990480711889 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.977210827616757 bayes_pls_golite062009
  • ligase activity
    		•  0.827063849687833 bayes_pls_golite062009
  • DNA binding
    		•  0.803965264969424 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.699955808682622 bayes_pls_golite062009
  • carbon-sulfur lyase activity
    		•  0.698312655247044 bayes_pls_golite062009
  • transcription factor activity
    		•  0.597417107954964 bayes_pls_golite062009
  • 5-aminolevulinate synthase activity
    		•  0.523223426448441 bayes_pls_golite062009
  • cystathionine gamma-lyase activity
    		•  0.505859361763689 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  0.50269055590758 bayes_pls_golite062009
  • binding
    		•  0.49769115245722 bayes_pls_golite062009
  • cystathionine beta-lyase activity
    		•  0.27933426619091 bayes_pls_golite062009
  • glycine hydroxymethyltransferase activity
    		•  0.271623203801431 bayes_pls_golite062009
  • O-phospho-L-serine:2-oxoglutarate aminotransferase activity
    		•  0.234399054481664 bayes_pls_golite062009
  • RNA binding
    		•  0.222777224430863 bayes_pls_golite062009
  • pyridoxal phosphate binding
    		•  0.16957228630576 bayes_pls_golite062009
  • vitamin B6 binding
    		•  0.16957228630576 bayes_pls_golite062009
  • sulfurtransferase activity
    		•  0.0450490929307473 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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