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Protein Overview: ORTH2_ARATH

General Information:
Name(s) found: ORTH2_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|22330295|ref|NP_176092.2| VIM1 (VARIANT IN METHYLATION 1); DNA binding / chromatin binding / double-stranded methylated DNA binding / histone binding / methyl-CpG binding / methyl-CpNpG binding / methyl-CpNpN binding / ubiquitin-protein ligase [Arabido [NCBI NR]
  • gi|21436127|gb|AAM51310.1| putative transcription factor [Arabidopsis thaliana] [NCBI NR]
  • gi|17529304|gb|AAL38879.1| putative transcription factor [Arabidopsis thaliana] [NCBI NR]
  • E3 ubiquitin-protein ligase ORTHRUS 2 OS=Arabidopsis thaliana GN=ORTH2 PE=1 SV=1 [Swiss-Prot]
  • putative transcription factor [Arabidopsis thaliana]gi|17529304|gb|AAL38879.1| putative transcription factor [Arabidopsis thaliana]gi|22330295|ref|NP_176092.2| zinc finger (C3HC4-type RING finger) family protein [Arabidopsis thaliana] [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Zinc finger (C3HC4-type RING finger) family protein [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: VIM1, ORTH2 | ORTH2/VIM1 (VARIANT IN METHYLATION 1); DNA binding / chromatin binding / double-stranded methylated DNA binding / histone binding / methyl-CpG binding / methyl-CpNpG binding / methyl-CpNpN binding | chr1:21418007-21421567 REVERSE [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • DNA binding / protein binding / ubiquitin-protein ligase/ zinc ion binding [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • putative transcription factor [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: VIM1, ORTH2 | Zinc finger (C3HC4-type RING finger) family protein | chr1:21414342-21417902 REVERSE LENGTH=645 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 645 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    chromocenter [IDA]
    Biological Process: cell division [IDA]
    centromeric heterochromatin formation [IMP]
    regulation of transcription, DNA-dependent [ISS]
    chromatin organization [IPI]
    DNA methylation on cytosine [IMP]
    protein ubiquitination [IDA]
    Molecular Function: DNA binding [ISS]
    ubiquitin-protein ligase activity [IDA]
    double-stranded methylated DNA binding [IDA]
    methyl-CpNpG binding [IDA]
    histone binding [IPI]
    methyl-CpNpN binding [IDA]
    chromatin binding [IDA]
    methyl-CpG binding [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MARDIQLPCD GDGVCMRCKS NPPPEESLTC GTCVTPWHVS CLSSPPKTLA STLQWHCPDC  60
   61 SGEIDPLPVS GGATGFESAG SDLVAAIRAI EADESLSTEE KAKMRQRLLS GKGVEEDDEE 120
  121 EKRKKKGKGK NPNLDVLSAL GDNLMCSFCM QLPERPVTKP CGHNACLKCF EKWMGQGKRT 180
  181 CGKCRSIIPE KMAKNPRINS SLVAAIRLAK VSKSAAATTS KVFHFISNQD RPDKAFTTER 240
  241 AKKTGKANAA SGKIYVTIPP DHFGPIPAEN DPVRNQGLLV GESWEDRLEC RQWGAHFPHV 300
  301 AGIAGQSTYG AQSVALSGGY KDDEDHGEWF LYTGSGGRDL SGNKRTNKEQ SFDQKFEKSN 360
  361 AALKLSCKLG YPVRVVRSHK EKRSAYAPEE GVRYDGVYRI EKCWRKVGVQ GSFKVCRYLF 420
  421 VRCDNEPAPW TSDENGDRPR PIPNIPELNM ATDLFERKET PSWDFDEGEG CWKWMKPPPA 480
  481 SKKSVNVLAP EERKNLRKAI KAAHSNTMRA RLLKEFKCQI CQQVLTLPVT TPCAHNFCKA 540
  541 CLEAKFAGKT LVRERSTGGR TLRSRKNVLN CPCCPTDISD FLQNPQVNRE VAEVIEKLKT 600
  601 QEEDTAELED EDEGECSGTT PEEDSEQPKK RIKLDTDATV SATIR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..118] FFAS03 2.98 No description for 2e6rA was found.
    2 View Details [119..263] PSI-BLAST 18.69897 RAG1 DIMERIZATION DOMAIN
    3 View Details [264..410] Pfam 43.920819 No description for PF02182.8 was found. No confident structure predictions are available.
    4 View Details [411..645] FFAS03 2.11 No description for 2f42A was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle