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The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine. The covalent transfer of a methyl group to C-5 or N-4 of cytosine in a DNA molecule. The addition of alkyl groups to many positions on all four bases of DNA. Alkylating agents can also modify the bases of incoming nucleotides in the course of DNA synthesis. The covalent transfer of a methyl group to C-5 of cytosine in a DNA molecule. The covalent transfer of a methyl group to N-4 of cytosine in a DNA molecule. The covalent attachment of a methyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule. The covalent transfer of a methyl group to C-5 or N-4 of a cytosine located within a CG sequence in a DNA molecule. Any process that modulates the frequency, rate or extent of gene expression; the process is mitotically or meiotically heritable, or is stably self-propagated in the cytoplasm of a resting cell, and does not entail a change in DNA sequence. The covalent transfer of a methyl group, to C-5 or N-4, of a cytosine located within a CNG sequence in a DNA molecule. N stands for any nucleotide. The covalent transfer of a methyl group, to C-5 or N-4, of a cytosine located within an asymmetric CHH sequence in a DNA molecule. H stands for an adenine, cytosine, or thymine nucleotide.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: DNA methylation on cytosine
Acc: GO:0032776
Aspect: Biological Process
Desc: The covalent transfer of a methyl group to C-5 or N-4 of cytosine in a DNA molecule.
Synonyms:
  • cytosine methylation
Proteins in PDR annotated with:
   This term: 7 [Search]
   Term or descendants: 16 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0032776 - DNA methylation on cytosine (interactive image map)
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