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Protein Overview: LEUC_ARATH

General Information:
Name(s) found: LEUC_ARATH [Swiss-Prot]
Description(s) found:
Found 12 descriptions.
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  • 3-isopropylmalate dehydratase large subunit OS=Arabidopsis thaliana GN=IIL1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 509 amino acids

    Gene Ontology:
    Cellular Component: chloroplast stroma [IDA]
    chloroplast [IDA]
    Biological Process: metabolic process [ISS]
    response to cadmium ion [IEP]
    Molecular Function: hydro-lyase activity [IEA]
    lyase activity [ISS]
    4 iron, 4 sulfur cluster binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASVISSSPF LCKSSSKSDL GISSFPKSSQ ISIHRCQKKS ISRKIVSVMA PQKDRSPGTT  60
   61 GSVKTGMTMT EKILARASEK SLVVPGDNIW VNVDVLMTHD VCGPGAFGIF KREFGEKAKV 120
  121 WDPEKIVVIP DHYIFTADKR ANRNVDIMRE HCREQNIKYF YDITDLGNFK ANPDYKGVCH 180
  181 VALAQEGHCR PGEVLLGTDS HTCTAGAFGQ FATGIGNTDA GFVLGTGKIL LKVPPTMRFI 240
  241 LDGEMPSYLQ AKDLILQIIG EISVAGATYK TMEFSGTTIE SLSMEERMTL CNMVVEAGGK 300
  301 NGVIPPDATT LNYVENRTSV PFEPVYSDGN ASFVADYRFD VSKLEPVVAK PHSPDNRALA 360
  361 RECKDVKIDR VYIGSCTGGK TEDFMAAAKL FHAAGRKVKV PTFLVPATQK VWMDVYALPV 420
  421 PGAGGKTCAQ IFEEAGCDTP ASPSCGACLG GPADTYARLN EPQVCVSTTN RNFPGRMGHK 480
  481 EGQIYLASPY TAAASALTGR VADPREFLQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..509] PSI-BLAST 136.0 Structure of an orthorhombic crystal form of human cytosolic aconitase (IRP1)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • 3-isopropylmalate dehydratase activity
    		•  11.6597692115322 bayes_pls_golite062009
  • catalytic activity
    		•  2.4040324437254 bayes_pls_golite062009
  • carbon-oxygen lyase activity
    		•  2.08349115784849 bayes_pls_golite062009
  • hydro-lyase activity
    		•  2.04845291489052 bayes_pls_golite062009
  • lyase activity
    		•  2.0080619912194 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.952569345633996 bayes_pls_golite062009
  • aconitate hydratase activity
    		•  0.681826117995502 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.0023376634609541 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.78

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle