Protein Overview: MMP2_RAT

General Information:
Name(s) found:	MMP2_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|49256641\|gb\|AAH74013.1\| Mmp2 protein [Rattus norvegicus] [NCBI NR] gi\|1813503\|gb\|AAB41692.1\| gelatinase A [Rattus norvegicus] [NCBI NR] gi\|149032698\|gb\|EDL87568.1\| matrix metallopeptidase 2 [Rattus norvegicus] [NCBI NR] gi\|146345459\|sp\|P33436.2\|MMP2_RAT RecName: Full=72 kDa type IV collagenase; AltName: Full=72 kDa gelatinase; AltName: Full=Matrix metalloproteinase-2; Short=MMP-2; AltName: Full=Gelatinase A; Flags: Precursor [NCBI NR] gi\|146262019\|ref\|NP_112316.2\| matrix metalloproteinase 2 [Rattus norvegicus] [NCBI NR] 72 kDa type IV collagenase OS=Rattus norvegicus GN=Mmp2 PE=2 SV=2 [Swiss-Prot] Unknown (protein for MGC:91653) [Rattus norvegicus]gi\|1813503\|gb\|AAB41692.1\| gelatinase A [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Mmp2 protein [EBI-IPI_rat_3.13_12-01-2005_con_reversed.fasta] matrix metallopeptidase 2 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] 72 kDa type IV collagenase precursor (72 kDa gelatinase) (Matrix metalloproteinase-2) (MMP-2) (Gelatinase A) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Mmp2 protein [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] gelatinase A [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] matrix metalloproteinase 2 [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Mmp2 72 kDa type IV collagenase [rat-ipi-250309-contam.fasta] 72 kDa type IV collagenase OS=Rattus norvegicus GN=Mmp2 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	662 amino acids
Gene Ontology:
Cellular Component:	nucleus [IEA] extracellular space [UNKNOWN] cytoplasm [IDA] intracellular membrane-bounded organelle [UNKNOWN] membrane [IEA] extracellular region [IEA] proteinaceous extracellular matrix [IEA] plasma membrane [UNKNOWN] sarcomere [UNKNOWN]
Biological Process:	response to cytokine stimulus [IEP] axon regeneration in the peripheral nervous system [IDA] response to estrogen stimulus [IDA] negative regulation of cell adhesion [IDA] metabolic process [IEA] response to hydrogen peroxide [IDA] aging [IEP] skeletal system morphogenesis [UNKNOWN] bone trabecula formation [UNKNOWN] face morphogenesis [UNKNOWN] ovarian follicle development [IDA] response to mechanical stimulus [IDA] ovulation from ovarian follicle [IEP] tissue remodeling [IDA] response to oxidative stress [IDA] response to hypoxia [UNKNOWN][IDA] angiogenesis [IEP] blood vessel maturation [UNKNOWN] response to drug [IDA] proteolysis [IDA] positive regulation of apoptosis [IDA] intramembranous ossification [UNKNOWN] collagen catabolic process [UNKNOWN][IEA] cell growth [IEP]
Molecular Function:	zinc ion binding [IEA] protein binding [UNKNOWN] metal ion binding [IEA] fibronectin binding [IPI] peptidase activity [IEA] metalloendopeptidase activity [UNKNOWN][IEA] metallopeptidase activity [TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEARLVWGVL VGPLRVLCVL CCLLGHAIAA PSPIIKFPGD VSPKTDKELA VQYLNTFYGC  60
   61 PKESCNLFVL KDTLKKMQKF FGLPQTGDLD QNTIETMRKP RCGNPDVANY NFFPRKPKWD 120
  121 KNQITYRIIG YTPDLDPETV DDAFARALKV WSDVTPLRFS RIHDGEADIM INFGRWEHGD 180
  181 GYPFDGKDGL LAHAFAPGTG VGGDSHFDDD ELWTLGEGQV VRVKYGNADG EYCKFPFLFN 240
  241 GREYSSCTDT GRSDGFLWCS TTYNFEKDGK YGFCPHEALF TMGGNGDGQP CKFPFRFQGT 300
  301 SYNSCTTEGR TDGYRWCGTT EDYDRDKKYG FCPETAMSTV GGNSEGAPCV FPFTFLGNKY 360
  361 ESCTSAGRSD GKVWCATTTN YDDDRKWGFC PDQGYSLFLV AAHEFGHAMG LEHSQDPGAL 420
  421 MAPIYTYTKN FRLSNDDIKG IQELYGPSPD ADTDTGTGPT PTLGPVTPEI CKQDIVFDGI 480
  481 AQIRGEIFFF KDRFIWRTVT PRDKPTGPLL VATFWPELPE KIDAVYEAPQ EEKAVFFAGN 540
  541 EYWVYSASTL ERGYPKPLTS LGLPPDVQQV DAAFNWSKNK KTYIFSGDKF WRYNEVKKKM 600
  601 DPGFPKLIAD SWNAIPDNLD AVVDLQGGGH SYFFKGAYYL KLENQSLKSV KFGSIKSDWL 660
  661 GC

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: MMP2_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: