Protein Overview: heph-PM

General Information:
Name(s) found:	heph-PM / FBpp0111778 [FlyBase]
Description(s) found: Found 17 descriptions. SHOW ALL	The gene hephaestus is referred to in FlyBase by the symbol Dmel\heph (CG31000, FBgn0011224). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:27676704..27819000. It has the cytological map location 100D3-100E1. Based on sequence similarity, it is predicted to have molecular function</span>: poly-pyrimidine tract binding; mRNA binding. There is experimental evidence that it is involved in the biological process</span>: spermatid development; imaginal disc-derived wing margin morphogenesis; imaginal disc-derived wing vein morphogenesis; Notch signaling pathway. 103 alleles are reported. The phenotypes of these alleles are annotated with: macrochaeta; testis; wing; individualization stage spermatid; spermatozoon. It has 22 annotated transcripts and 22 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	568 amino acids
Gene Ontology:
Cellular Component:	nucleus [IEA] ribonucleoprotein complex [IDA] cytoplasm [IDA]
Biological Process:	negative regulation of oskar mRNA translation [IMP] Notch signaling pathway [IMP] spermatid development [IMP] imaginal disc-derived wing margin morphogenesis [IMP] oocyte microtubule cytoskeleton polarization [IMP] imaginal disc-derived wing vein morphogenesis [IMP] nuclear mRNA splicing, via spliceosome [ISS]
Molecular Function:	nucleotide binding [IEA] poly-pyrimidine tract binding [ISS][NAS] translation repressor activity, nucleic acid binding [IMP] mRNA binding [ISS] mRNA 3'-UTR binding [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPASDNNNQ DLATKKAKLE PGTVLAGGIA KASKVIHLRN IPNESGEADV IALGIPFGRV  60
   61 TNVLVLKGKN QAFIEMADEI SATSMVSCYT VTPPQMRGRM VYVQFSNHRE LKTDQGHNNS 120
  121 TAHSDYSVQS PASGSPLPLS AAANATSNNA NSSSDSNSAM GILQNTSAVN AGGNTNAAGG 180
  181 PNTVLRVIVE SLMYPVSLDI LHQIFQRYGK VLKIVTFTKN NSFQALIQYP DANSAQHAKS 240
  241 LLDGQNIYNG CCTLRIDNSK LTALNVKYNN DKSRDFTNPA LPPGEPGVDI MPTAGGLMNT 300
  301 NDLLLIAARQ RPSLSGDKIV NGLGAPGVLP PFALGLGTPL TGGYNNALPN LAAFSLANSG 360
  361 ALQTTAPAMR GYSNVLLVSN LNEEMVTPDA LFTLFGVYGD VQRVKILYNK KDSALIQMAE 420
  421 PQQAYLAMSH LDKLRLWGKP IRVMASKHQA VQLPKEGQPD AGLTRDYSQN PLHRFKKPGS 480
  481 KNYQNIYPPS ATLHLSNIPS SCSEDDIKEA FTSNSFEVKA FKFFPKDRKM ALLQLLSVEE 540
  541 AVLALIKMHN HQLSESNHLR VSFSKSNI

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.95

Protein Overview: heph-PM

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: