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Protein Overview: gi|151567604, gi...

General Information:
Name(s) found: gi|28373999 [NCBI NR]
gi|151567606 [NCBI NR]
gi|151567605 [NCBI NR]
gi|151567604 [NCBI NR]
Description(s) found:
Found 5 descriptions.
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  • gi|28373999|pdb|1NEP|A Chain A, Crystal Structure Analysis Of The Bovine Npc2 (Niemann-Pick C2) Protein [NCBI NR]
  • gi|151567606|pdb|2HKA|C Chain C, Crystal Structure Of Bovine Npc2 And Cholesterol Sulfate Complex [NCBI NR]
  • gi|151567605|pdb|2HKA|B Chain B, Crystal Structure Of Bovine Npc2 And Cholesterol Sulfate Complex [NCBI NR]
  • gi|151567604|pdb|2HKA|A Chain A, Crystal Structure Of Bovine Npc2 And Cholesterol Sulfate Complex [NCBI NR]
    • Organism: Bos taurus
    Length: 130 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EPVKFKDCGS WVGVIKEVNV SPCPTQPCKL HRGQSYSVNV TFTSNTQSQS SKAVVHGIVM  60
   61 GIPVPFPIPE SDGCKSGIRC PIEKDKTYNY VNKLPVKNEY PSIKVVVEWE LTDDKNQRFF 120
  121 CWQIPIEVEA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..130] PSI-BLAST 39.09691 Epididymal secretory protein E1 (Niemann-Pick C2 protein)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.45696367038333 bayes_pls_golite062009
  • ligand-gated channel activity
    		•  1.76150217842113 bayes_pls_golite062009
  • ligand-gated ion channel activity
    		•  1.76150217842113 bayes_pls_golite062009
  • protein binding
    		•  1.40303524581236 bayes_pls_golite062009
  • cholesterol binding
    		•  1.06647503454536 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.929966017205863 bayes_pls_golite062009
  • potassium channel activity
    		•  0.871728492941793 bayes_pls_golite062009
  • voltage-gated cation channel activity
    		•  0.848303301157398 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  0.829939555243379 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.829140804686535 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  0.820413268771765 bayes_pls_golite062009
  • channel activity
    		•  0.796075411518814 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  0.796075411518814 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  0.790863065462458 bayes_pls_golite062009
  • voltage-gated potassium channel activity
    		•  0.787347074261486 bayes_pls_golite062009
  • cation channel activity
    		•  0.770955130885998 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.760234877475175 bayes_pls_golite062009
  • ion channel activity
    		•  0.743051345681968 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  0.735623329949285 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.698762820554681 bayes_pls_golite062009
  • hydrolase activity
    		•  0.62707426744686 bayes_pls_golite062009
  • gated channel activity
    		•  0.62499749903999 bayes_pls_golite062009
  • inward rectifier potassium channel activity
    		•  0.43450134854604 bayes_pls_golite062009
  • sterol binding
    		•  0.396392013320299 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.20266751601478 bayes_pls_golite062009
  • receptor binding
    		•  0.0582281681682861 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle