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Protein Overview: LEU31_ARATH

General Information:
Name(s) found: LEU31_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|15221631|ref|NP_174403.1| 3-isopropylmalate dehydrogenase, chloroplast, putative [Arabidopsis thaliana] [NCBI NR]
  • gi|148887392|sp|Q9SA14.2|LEU31_ARATH RecName: Full=3-isopropylmalate dehydrogenase 1, chloroplastic; Short=3-IPM-DH 1; Short=IMDH 1; AltName: Full=Beta-IPM dehydrogenase 1; Flags: Precursor [NCBI NR]
  • gi|109134129|gb|ABG25063.1| At1g31180 [Arabidopsis thaliana] [NCBI NR]
  • 3-isopropylmalate dehydrogenase 1, chloroplastic OS=Arabidopsis thaliana GN=IMDH1 PE=2 SV=2 [Swiss-Prot]
  • 3-isopropylmalate dehydrogenase, chloroplast, putative [Arabidopsis thaliana] [nrdb_11152004_Chlamydomonas]
  • | Symbols: | 3-isopropylmalate dehydrogenase, chloroplast, putative | chr1:11142824-11144598 REVERSE [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • At1g31180 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • 3-isopropylmalate dehydrogenase/ oxidoreductase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: ATIMD3, IMD3, IPMDH1 | isopropylmalate dehydrogenase 3 | chr1:11142843-11144617 REVERSE LENGTH=404 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 404 amino acids

    Gene Ontology:
    Cellular Component: chloroplast stroma [IDA]
    chloroplast [IDA]
    plastid [IDA][ISS]
    thylakoid [IDA]
    Biological Process: response to salt stress [IEP]
    metabolic process [ISS]
    leucine biosynthetic process [IGI]
    Molecular Function: 3-isopropylmalate dehydrogenase activity [IGI][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAFLQTNIR LEIIPGRYSS LTDHKFRAPY RIRCAAASPV KKRYNITLLP GDGIGPEVIS  60
   61 VAKNVLQKAG FLQGLEFDFQ EMPFGGAALD LVGVPLPEET STAAKQSDAI LLGAIGGYKW 120
  121 DKNEKHLRPE MGLLNIRRDL NVFANLRPAT VLPQLVDAST LKKEVAQGVD MMIVRELTGG 180
  181 IYFGEPRGIT INENGEEVGF NTEIYAAHEI DRIARVAFET ARKRRGKLCS VDKANVLDAS 240
  241 ILWRKRVTAL ASEYPDVELS HMYVDNAAMQ LVRDPKQFDT IVTNNIFGDI LSDEASMITG 300
  301 SIGMLPSASL GESGPGLFEP IHGSAPDIAG QDKANPLATI LSAAMLLKYG LGEEKAAKMI 360
  361 EDAVVDALNK GFRTGDIYSP GNKLVGCKEM GEEVLKSVDS KVPV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..404] PSI-BLAST 124.0 3-isopropylmalate dehydrogenase, IPMDH

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • isocitrate dehydrogenase (NAD+) activity
    		•  5.9567768649084 bayes_pls_golite062009
  • isocitrate dehydrogenase activity
    		•  5.76817846591752 bayes_pls_golite062009
  • 3-isopropylmalate dehydrogenase activity
    		•  4.43187390953534 bayes_pls_golite062009
  • isocitrate dehydrogenase (NADP+) activity
    		•  3.47645456015586 bayes_pls_golite062009
  • malate dehydrogenase activity
    		•  3.17013707624362 bayes_pls_golite062009
  • oxidoreductase activity
    		•  2.74237430402883 bayes_pls_golite062009
  • catalytic activity
    		•  2.71251959637136 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  2.46799258909805 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  2.38235863668553 bayes_pls_golite062009
  • binding
    		•  1.19820115767498 bayes_pls_golite062009
  • malic enzyme activity
    		•  0.483776792839856 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  0.466038297142601 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle