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Protein Overview: gi|42573315, gi|...

General Information:
Name(s) found: gi|42573315 [NCBI NR]
gi|30682591 [NCBI NR]
Description(s) found:
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  • gi|42573315|ref|NP_974754.1| SRT2 (SIRTUIN 2); DNA binding / NAD or NADH binding / NAD-dependent histone deacetylase/ zinc ion binding [Arabidopsis thaliana] [NCBI NR]
  • gi|30682591|ref|NP_850797.1| SRT2 (SIRTUIN 2); DNA binding / NAD or NADH binding / NAD-dependent histone deacetylase/ zinc ion binding [Arabidopsis thaliana] [NCBI NR]
  • transcriptional regulator Sir2 family protein [Arabidopsis thaliana]gi|42573315|ref|NP_974754.1| transcriptional regulator Sir2 family protein [Arabidopsis thaliana] [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Transcriptional regulator Sir2 family protein [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: SRT2 | SRT2; DNA binding | chr5:2872182-2873614 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • DNA binding [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: SRT2 | sirtuin 2 | chr5:2872181-2873613 FORWARD LENGTH=271 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
  • Sirtuin 2 OS=Arabidopsis thaliana GN=SRT2 PE=4 SV=1 [ARATH-contam.fasta]
  • Isoform of Q94AQ6, Sirtuin 2 OS=Arabidopsis thaliana GN=SRT2 PE=4 SV=1 [ARATH.fasta.20160308]
    • Organism: Arabidopsis thaliana
    Length: 271 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: regulation of transcription, DNA-dependent [IEA]
    protein amino acid deacetylation [IEA]
    chromatin silencing [IEA]
    Molecular Function: DNA binding [IEA]
    zinc ion binding [IEA]
    NAD or NADH binding [IEA]
    NAD-dependent histone deacetylase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWNSGLQKSQ WSIQFWFQTN YPSGDLKEFT RSSRARRRYW ARSYAGWRRF TAAQPGPAHT  60
   61 ALASLEKAGR INFMITQNVD RLHHRAGSDP LELHGTVYTV MCLECGFSFP RDLFQDQLKA 120
  121 INPKWAEAIE SIDHGDPGSE KSFGMKQRPD GDIEIDEKFW EEGFHIPVCE KCKGVLKPDV 180
  181 IFFGDNIPKE RATQAMEVAK QSDAFLVLGS SLMTMSAFRL CRAAHEAGAM TAIVNIGETR 240
  241 ADDIVPLKIN ARVGEILHRV LDVGSLSVPA L

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..271] PSI-BLAST 70.09691 AF1676, Sir2 homolog (Sir2-AF1?)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  1.35219834199205 bayes_pls_golite062009
  • catalytic activity
    		•  1.1096503360938 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.798062126041325 bayes_pls_golite062009
  • DNA binding
    		•  0.76914567174665 bayes_pls_golite062009
  • binding
    		•  0.725903081591757 bayes_pls_golite062009
  • NAD-dependent histone deacetylase activity
    		•  0.5748958272185 bayes_pls_golite062009
  • NAD-dependent protein deacetylase activity
    		•  0.5748958272185 bayes_pls_golite062009
  • histone deacetylase activity
    		•  0.417995543117071 bayes_pls_golite062009
  • protein deacetylase activity
    		•  0.40196400477198 bayes_pls_golite062009
  • deacetylase activity
    		•  0.154033944993939 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle