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Protein Overview: KPCB_RAT

General Information:
Name(s) found: KPCB_RAT [Swiss-Prot]
Description(s) found:
Found 6 descriptions.
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  • Protein kinase C beta type OS=Rattus norvegicus GN=Prkcb PE=1 SV=3 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 671 amino acids

    Gene Ontology:
    Cellular Component: membrane fraction [IDA]
    nucleus [UNKNOWN][ISS]
    centrosome [IDA]
    soluble fraction [IDA]
    brush border membrane [IDA]
    cytoplasm [UNKNOWN][IEA]
    membrane [IEA]
    cytosol [UNKNOWN]
    plasma membrane [UNKNOWN]
    Biological Process: regulation of dopamine secretion [IMP]
    chromatin modification [IEA]
    response to vitamin D [IEP]
    positive regulation of I-kappaB kinase/NF-kappaB cascade [ISS]
    B cell activation [ISS]
    protein amino acid phosphorylation [UNKNOWN][IEA]
    positive regulation of odontogenesis of dentine-containing tooth [IEP]
    regulation of transcription [IEA]
    regulation of growth [IMP]
    cellular calcium ion homeostasis [UNKNOWN]
    response to ethanol [IEP]
    response to glucose stimulus [IEP]
    intracellular signaling pathway [NAS]
    histone H3-T6 phosphorylation [UNKNOWN]
    response to drug [IMP]
    calcium ion transport [UNKNOWN]
    apoptosis [IEA]
    regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor [UNKNOWN][ISS]
    B cell receptor signaling pathway [ISS]
    Molecular Function: protein kinase C binding [UNKNOWN]
    zinc ion binding [IEA]
    chromatin binding [UNKNOWN][ISS]
    calcium channel regulator activity [UNKNOWN]
    protein kinase C activity [UNKNOWN][IDA]
    nucleotide binding [IEA]
    ATP binding [IEA]
    protein binding [UNKNOWN][IDA][IPI]
    androgen receptor binding [UNKNOWN][ISS]
    histone binding [UNKNOWN][ISS]
    metal ion binding [IEA]
    ligand-dependent nuclear receptor transcription coactivator activity [UNKNOWN][ISS]
    transferase activity [IEA]
    histone kinase activity (H3-T6 specific) [UNKNOWN]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADPAAGPPP SEGEESTVRF ARKGALRQKN VHEVKNHKFT ARFFKQPTFC SHCTDFIWGF  60
   61 GKQGFQCQVC CFVVHKRCHE FVTFSCPGAD KGPASDDPRS KHKFKIHTYS SPTFCDHCGS 120
  121 LLYGLIHQGM KCDTCMMNVH KRCVMNVPSL CGTDHTERRG RIYIQAHIDR EVLIVVVRDA 180
  181 KNLVPMDPNG LSDPYVKLKL IPDPKSESKQ KTKTIKCSLN PEWNETFRFQ LKESDKDRRL 240
  241 SVEIWDWDLT SRNDFMGSLS FGISELQKAG VDGWFKLLSQ EEGEYFNVPV PPEGSEGNEE 300
  301 LRQKFERAKI GQGTKAPEEK TANTISKFDN NGNRDRMKLT DFNFLMVLGK GSFGKVMLSE 360
  361 RKGTDELYAV KILKKDVVIQ DDDVECTMVE KRVLALPGKP PFLTQLHSCF QTMDRLYFVM 420
  421 EYVNGGDLMY HIQQVGRFKE PHAVFYAAEI AIGLFFLQSK GIIYRDLKLD NVMLDSEGHI 480
  481 KIADFGMCKE NIWDGVTTKT FCGTPDYIAP EIIAYQPYGK SVDWWAFGVL LYEMLAGQAP 540
  541 FEGEDEDELF QSIMEHNVAY PKSMSKEAVA ICKGLMTKHP GKRLGCGPEG ERDIKEHAFF 600
  601 RYIDWEKLER KEIQPPYKPK ARDKRDTSNF DKEFTRQPVE LTPTDKLFIM NLDQNEFAGF 660
  661 SYTNPEFVIN V

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle