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Protein Overview: gi|22218837

General Information:
Name(s) found: gi|22218837 [NCBI NR]
Description(s) found:
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  • gi|22218837|pdb|1JE6|A Chain A, Structure Of The Mhc Class I Homolog Micb [NCBI NR]
  • Chain A, Structure Of The Mhc Class I Homolog Micb [nrdb_11152004_Chlamydomonas]
    • Organism: Homo sapiens
    Length: 275 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEPHSLRYNL MVLSQDGSVQ SGFLAEGHLD GQPFLRYDRQ KRRAKPQGQW AEDVLGAETW  60
   61 DTETEDLTEN GQDLRRTLTH IKDQKGGLHS LQEIRVCEIH EDSSTRGSRH FYYNGELFLS 120
  121 QNLETQESTV PQSSRAQTLA MNVTNFWKED AMKTKTHYRA MQADCLQKLQ RYLKSGVAIR 180
  181 RTVPPMVNVT CSEVSEGNIT VTCRASSFYP RNITLTWRQD GVSLSHNTQQ WGDVLPDGNG 240
  241 TYQTWVATRI RQGEEQRFTC YMEHSGNHGT HPVPS

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Noble WS, et al. (2009) Manuscript in preparation. gi|112491310 gi|22218837

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..275] PSI-BLAST 54.69897 Class I MHC homolog, alpha-3 domain; Class I MHC homolog

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • peptide antigen binding
    		•  11.0753660234769 bayes_pls_golite062009
  • olfactory receptor activity
    		•  10.396146040408 bayes_pls_golite062009
  • antigen binding
    		•  4.70353060278319 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  4.47335611545936 bayes_pls_golite062009
  • receptor activity
    		•  4.41760011727341 bayes_pls_golite062009
  • endogenous lipid antigen binding
    		•  3.8178682806181 bayes_pls_golite062009
  • G-protein coupled receptor activity
    		•  3.81042605880111 bayes_pls_golite062009
  • molecular transducer activity
    		•  3.44808015198907 bayes_pls_golite062009
  • signal transducer activity
    		•  3.44808015198907 bayes_pls_golite062009
  • lipid antigen binding
    		•  3.36458164702861 bayes_pls_golite062009
  • natural killer cell lectin-like receptor binding
    		•  2.87337850935774 bayes_pls_golite062009
  • MHC class I receptor activity
    		•  2.8317290648207 bayes_pls_golite062009
  • fibroblast growth factor 1 binding
    		•  2.64517375056633 bayes_pls_golite062009
  • IgG binding
    		•  2.59905791929203 bayes_pls_golite062009
  • peptide binding
    		•  2.55584703989799 bayes_pls_golite062009
  • protein binding
    		•  2.20481087437436 bayes_pls_golite062009
  • exogenous lipid antigen binding
    		•  2.20171675099945 bayes_pls_golite062009
  • receptor binding
    		•  2.03767222253534 bayes_pls_golite062009
  • immunoglobulin receptor activity
    		•  2.03064643363242 bayes_pls_golite062009
  • binding
    		•  1.90626658068048 bayes_pls_golite062009
  • fibroblast growth factor binding
    		•  1.78492923920341 bayes_pls_golite062009
  • growth factor binding
    		•  1.60826091835429 bayes_pls_golite062009
  • IgG receptor activity
    		•  1.15013317153047 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.951547821168483 bayes_pls_golite062009
  • IgE binding
    		•  0.92099524949571 bayes_pls_golite062009
  • IgE receptor activity
    		•  0.92099524949571 bayes_pls_golite062009
  • coreceptor activity
    		•  0.661209696849389 bayes_pls_golite062009
  • cell adhesion molecule binding
    		•  0.63737386998612 bayes_pls_golite062009
  • cytokine binding
    		•  0.631436442105379 bayes_pls_golite062009
  • integrin binding
    		•  0.599569390248921 bayes_pls_golite062009
  • transmembrane receptor protein kinase activity
    		•  0.447829399094714 bayes_pls_golite062009
  • cytokine receptor activity
    		•  0.34165331857492 bayes_pls_golite062009
  • DNA binding
    		•  0.32716145688038 bayes_pls_golite062009
  • transmembrane receptor protein tyrosine kinase activity
    		•  0.28309679787333 bayes_pls_golite062009
  • MHC class II receptor activity
    		•  0.251167772391909 bayes_pls_golite062009
  • catalytic activity
    		•  0.115804452291889 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle