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View Structure Prediction Details

Protein: bl-PC
Organism: Drosophila melanogaster
Length: 502 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for bl-PC.

Description E-value Query
Range
Subject
Range
gi|113461768, gi... - gi|113461768|ref|YP_719837.1| large adhesin [Haemophilus somnus 129PT], gi|112823811|gb|ABI25900.1| ...
247.0 [0..114] [451..1450]

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Predicted Domain #1
Region A:
Residues: [1-132]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTKRLRMKRE MNDEGEGPQD QKRNRRNEET VRILIPSSIA GAVIGKGGQH IQKMRTQYKA  60
   61 TVSVDDSQGP ERTIQISADI ESTLEIITEM LKYFEERDED FDVRLLIHQS LAGCVIGKGG 120
  121 QKIKEIRDRI GC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 26.39794
Match: 2annA
Description: No description for 2annA was found.

Predicted Domain #2
Region A:
Residues: [133-443]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RFLKVFSNVA PQSTDRVVQT VGKQSQVIEA VREVITLTRD TPIKGAIHNY DPMNFDRVYA  60
   61 DEYGGYGTGS GSTRPSQRGN NRNGGGAGGV AGGAAGGNGG GFNAGGARGN AGGRGGADRF 120
  121 GGAAGGAVAG AGMGQRDNPF INPWANGGGG DVDGFGNNAG GAGGFAGNSF GGGAGGPFGG 180
  181 GSFGNNGFGG GPSDFGGNSG NFGQAQGTNS LPSLGSFSQN QGGTSSLPSL GSFGQNPGGP 240
  241 GGLGNGLSGG ANGGVGTLGG ANGAGGFNAV GGANGGPNGS PNAATNVPQG HDPNNSTQVT 300
  301 IPKELAGAII G

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.154902
Match: 1y0fB
Description: No description for 1y0fB was found.

Predicted Domain #3
Region A:
Residues: [444-502]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KGGGRIRRIR NESSAYITID EPLPNSNDRI ITISGTPKQI QMAQYLLQQS VHENGRRNI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.39794
Match: 1j5kA
Description: HnRNP K, KH3
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.76415077523249 bayes_pls_golite062009
mRNA binding 5.07455187994216 bayes_pls_golite062009
nucleic acid binding 4.78650555542715 bayes_pls_golite062009
binding 3.45962790790935 bayes_pls_golite062009
2.87067043110488 bayes_pls_golite062009
transcription regulator activity 2.28364833275102 bayes_pls_golite062009
poly-pyrimidine tract binding 2.05765562493656 bayes_pls_golite062009
DNA binding 2.03207983673692 bayes_pls_golite062009
transcription factor activity 1.30278154718684 bayes_pls_golite062009
protein binding 1.16541072642796 bayes_pls_golite062009
single-stranded RNA binding 0.981003625136521 bayes_pls_golite062009
mRNA 3'-UTR binding 0.489176583045793 bayes_pls_golite062009
transcription repressor activity 0.392035003865213 bayes_pls_golite062009
transcription activator activity 0.324382863054631 bayes_pls_golite062009
structure-specific DNA binding 0.32222928997178 bayes_pls_golite062009
transcription factor binding 0.254024117548226 bayes_pls_golite062009
catalytic activity 0.113112541746059 bayes_pls_golite062009
single-stranded DNA binding 0.1069917291606 bayes_pls_golite062009
sequence-specific DNA binding 0.0321875054165348 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle