| Protein: | p53-PB |
| Organism: | Drosophila melanogaster |
| Length: | 495 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for p53-PB.
| Description | E-value | Query Range |
Subject Range |
|
|
631.0 | [0..1] | [495..25] |
|
Region A: Residues: [1-123] |
1 11 21 31 41 51
| | | | | |
1 MSLHKSASFS LTFNQNTSIV SRSNSRTIFE AFKEFLDFWD IGNEVSAESA VRVSSNGAFN 60
61 LPQSFGNESN EYAHLATPVD PAYGGNNTNN MMQFTNNLEI LANNNSDGNN KINACNKFVC 120
121 HKG
|
| Detection Method: |  |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [124-417] |
1 11 21 31 41 51
| | | | | |
1 TDSEDDSTEV DIKEDIPKTV EVSGSELTTE PMAFLQGLNS GNLMQFSQQS VLREMMLQDI 60
61 QIQANTLPKL ENHNIGGYCF SMVLDEPPKS LWMYSIPLNK LYIRMNKAFN VDVQFKSKMP 120
121 IQPLNLRVFL CFSNDVSAPV VRCQNHLSVE PLTANNAKMR ESLLRSENPN SVYCGNAQGK 180
181 GISERFSVVV PLNMSRSVTR SGLTRQTLAF KFVCQNSCIG RKETSLVFCL EKACGDIVGQ 240
241 HVIHVKICTC PKRDRIQDER QLNSKKRKSV PEAAEEDEPS KVRRCIAIKT EDTE
|
| Detection Method: | |
| Confidence: | 88.0 |
| Match: | 1uolA |
| Description: | Crystal structure of the human p53 core domain mutant M133L/V203A/N239Y/N268D at 1.9 A resolution. |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 5.42929256050781 | bayes_pls_golite062009 |
| DNA binding | 5.31133900263778 | bayes_pls_golite062009 |
| nucleic acid binding | 5.16722510757739 | bayes_pls_golite062009 |
| DNA strand annealing activity | 4.57315860395948 | bayes_pls_golite062009 |
| transcription factor activity | 4.50526425463039 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 3.91938513552138 | bayes_pls_golite062009 |
| transcription activator activity | 3.89749713667575 | bayes_pls_golite062009 |
| binding | 3.82913410895101 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 3.14317875446423 | bayes_pls_golite062009 |
| protein binding | 2.61625563263605 | bayes_pls_golite062009 |
| structure-specific DNA binding | 2.36676277465674 | bayes_pls_golite062009 |
| double-stranded DNA binding | 2.30995267491835 | bayes_pls_golite062009 |
| single-stranded DNA binding | 1.96307110502121 | bayes_pls_golite062009 |
| chromatin binding | 1.28001279726096 | bayes_pls_golite062009 |
| transcription repressor activity | 1.27337392672914 | bayes_pls_golite062009 |
| copper ion binding | 1.24203749926155 | bayes_pls_golite062009 |
| transcription factor binding | 0.628837188707778 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity, enhancer binding | 0.35905469882415 | bayes_pls_golite062009 |
| protein dimerization activity | 0.0889583851427092 | bayes_pls_golite062009 |
|
Region A: Residues: [418-495] |
1 11 21 31 41 51
| | | | | |
1 SNDSRDCDDS AAEWNVSRTP DGDYRLAITC PNKEWLLQSI EGMIKEAAAE VLRNPNQENL 60
61 RRHANKLLSL KKRAYELP
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
