






| Protein: | foxo-PC, foxo-PB |
| Organism: | Drosophila melanogaster |
| Length: | 613 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for foxo-PC, foxo-PB.
| Description | E-value | Query Range |
Subject Range |
|
|
159.0 | [0..210] | [612..1484] |
|
Region A: Residues: [1-202] |
1 11 21 31 41 51
| | | | | |
1 MMDGYAQEWP RLTHTDNGLA MDQLGGDLPL DVGFEPQTRA RSNTWPCPRP ENFVEPTDEL 60
61 DSTKASNQQL APGDSQQAIQ NANAAKKNSS RRNAWGNLSY ADLITHAIGS ATDKRLTLSQ 120
121 IYEWMVQNVP YFKDKGDSNS SAGWKNSIRH NLSLHNRFMR VQNEGTGKSS WWMLNPEAKP 180
181 GKSVRRRAAS METSRYEKRR GR
|
| Detection Method: | |
| Confidence: | 25.0 |
| Match: | 1e17A |
| Description: | Afx (Foxo4) |
Matching Structure (courtesy of the PDB):![]() |
|
| Term | Confidence | Notes |
| transcription regulator activity | 5.55329976718261 | bayes_pls_golite062009 |
| DNA binding | 5.08959163553491 | bayes_pls_golite062009 |
| nucleic acid binding | 4.99681957904233 | bayes_pls_golite062009 |
| transcription factor activity | 4.33152142980289 | bayes_pls_golite062009 |
| binding | 3.52874320222492 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 2.48053910222825 | bayes_pls_golite062009 |
| transcription activator activity | 2.37668609508629 | bayes_pls_golite062009 |
| transcription repressor activity | 2.22485867684613 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 1.70025468248325 | bayes_pls_golite062009 |
| transcription factor binding | 0.85714789329232 | bayes_pls_golite062009 |
| protein binding | 0.753698599635855 | bayes_pls_golite062009 |
| structure-specific DNA binding | 0.217544912085963 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 0.0856082199488197 | bayes_pls_golite062009 |
| specific transcriptional repressor activity | 0.0565989703351002 | bayes_pls_golite062009 |
|
Region A: Residues: [203-498] |
1 11 21 31 41 51
| | | | | |
1 AKKRVEALRQ AGVVGLNDAT PSPSSSVSEG LDHFPESPLH SGGGFQLSPD FRQRASSNAS 60
61 SCGRLSPIRA QDLEPDWGFP VDYQNTTMTQ AHAQALEELT GTMADELTLC NQQQQGFSAA 120
121 SGLPSQPPPP PYQPPQHQQA QQQQQQQSPY ALNGPASGYN TLQPQSQCLL HRSLNCSCMH 180
181 NARDGLSPNS VTTTMSPAYP NSEPSSDSLN TYSNVVLDGP ADTAALMVQQ QQQQQQQQQL 240
241 SASLEGQCLE VLNNEAQPID EFNLENFPVG NLECNVEELL QQEMSYGGLL DINIPL
|
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [499-613] |
1 11 21 31 41 51
| | | | | |
1 ATVNTNLVNS SSGPLSISNI SNLSNISSNS GSSLSLNQLQ AQLQQQQQQQ QAQQQQQAQQ 60
61 QQQQHQQHQQ QLLLNNNNNS SSSLELATQT ATTNLNARVQ YSQPSVVTSP PSWVH
|
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.