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View Structure Prediction Details

Protein: CG1640-PB
Organism: Drosophila melanogaster
Length: 575 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG1640-PB.

Description E-value Query
Range
Subject
Range
gi|17862964 - gi|17862964|gb|AAL39959.1| SD05601p [Drosophila melanogaster]
360.0 [0..8] [575..1]

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Predicted Domain #1
Region A:
Residues: [1-137]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFKNRKIMSR MLIKPAAATV SAALQQHQRQ QQQYVIRRWK SFLHNNSNNA NRRAAKSTAT  60
   61 ATVTAAATSQ RHGTSGDFIQ PLDVRRSFST SHKMPSSSKA LTLDNINPNF IAMEYAVRGP 120
  121 LVIRAGEIEK ELEKGVK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.522879
Match: 1v4rA
Description: Solution structure of Streptmycal repressor TraR
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.4536940012509 bayes_pls_golite062009
DNA binding 3.23093645092894 bayes_pls_golite062009
nucleic acid binding 3.20789737823268 bayes_pls_golite062009
binding 2.97484655729009 bayes_pls_golite062009
transcription factor activity 2.61062802798523 bayes_pls_golite062009
sequence-specific DNA binding 1.28754561517213 bayes_pls_golite062009
transcription activator activity 1.13682518056041 bayes_pls_golite062009
transcription repressor activity 0.99712200420162 bayes_pls_golite062009
protein binding 0.501337284874473 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.48900880427449 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [138-575]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPFDQVIRAN IGDCHAMGQQ PLTFLRQLLA LTFETRLLDS PDYPEDVKKR ACAILNGCQG  60
   61 QSVGSYTDSA GLEVVRRQVA QYIEKRDGGI ASNWQDIYLT GGASPGIKSI LSMINAEVGC 120
  121 KAPGVMVPIP QYPLYSATIS EYGMTKVDYY LEEETGWSLD RKELQRSYDE AKKVCNPRAL 180
  181 VVINPGNPTG QVLTRENIEE IIKFAHDNKV LVLADEVYQD NVYDKNSKFW SFKKVAYEMG 240
  241 DPYRNLEMVS FLSTSKGYLG ECGIRGGYME VLNLDPKVKA MLTKSITAAL CSTTAGQVAV 300
  301 SALVNPPQPG EPSYDLYKKE RDGILAALKE RAELVHKALN SFEGYKVNPV QGAMYVFPQI 360
  361 EIPPKAIEAA KAKGMAPDVF YAFELLETSG ICIVPGSGFG QKPGTWHFRS TILPQTDKLK 420
  421 LMMEKFRVFH AEFMKKYK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 70.69897
Match: 1xi9A
Description: Alanine aminotransferase from Pyrococcus furiosus Pfu-1397077-001
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
L-aspartate:2-oxoglutarate aminotransferase activity 5.51961002550688 bayes_pls_golite062009
catalytic activity 2.29878871754893 bayes_pls_golite062009
4-aminobutyrate transaminase activity 1.82501790383768 bayes_pls_golite062009
glycine dehydrogenase (decarboxylating) activity 1.63055151623667 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor 1.63055151623667 bayes_pls_golite062009
transferase activity 1.44093490824786 bayes_pls_golite062009
transferase activity, transferring nitrogenous groups 1.28316822767388 bayes_pls_golite062009
transaminase activity 1.24990480711889 bayes_pls_golite062009
L-alanine:2-oxoglutarate aminotransferase activity 1.06988190956423 bayes_pls_golite062009
alanine-oxo-acid transaminase activity 1.06988190956423 bayes_pls_golite062009
hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances 0.942545094747784 bayes_pls_golite062009
hydrolase activity, acting on acid carbon-carbon bonds 0.845816961387768 bayes_pls_golite062009
N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity 0.753443687983955 bayes_pls_golite062009
binding 0.536634592992536 bayes_pls_golite062009
transferase activity, transferring acyl groups 0.319452731970428 bayes_pls_golite062009
pyridoxal phosphate binding 0.16957228630576 bayes_pls_golite062009
vitamin B6 binding 0.16957228630576 bayes_pls_golite062009
aromatic-amino-acid:2-oxoglutarate aminotransferase activity 0.0916183433120769 bayes_pls_golite062009
kynureninase activity 0.0900983660305177 bayes_pls_golite062009
cystathionine beta-lyase activity 0.0833010353195099 bayes_pls_golite062009
nucleic acid binding 0.013097682076602 bayes_pls_golite062009

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