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Catalysis of the reaction: nonane-4,6-dione + H2O = pentan-2-one + butanoate. Catalysis of the reaction: cyclohexane-1,3-dione + H2O = 5-oxohexanoate. Catalysis of the reaction: 6-oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8-trichloroocta-2Z,4Z,7-trienoate + H2O = 2-(4'-chlorophenyl)-3,3-dichloropropenoate + cis-2-Hydroxy-3-chloropenta-2,4-dienone + H+. Catalysis of the reaction: 2,4,6-trioxoheptanoate + H2O = acetylpyruvate + acetate. Catalysis of the reaction: 2-hydroxy-6-keto-nona-2,4-dienedioate + OH- = cis-2-hydroxypenta-2,4-dienoate + succinate. Catalysis of the reaction: 2,6-dioxo-6-phenylhexa-3-enoate + H2O = benzoate + 2-oxopent-4-enoate. Catalysis of the reaction: L-kynurenine + H2O = anthranilate + L-alanine. Catalysis of the reaction: acetylpyruvate + H2O = acetate + pyruvate. Catalysis of the reaction: 2-hydroxymuconate semialdehyde + H2O = formate + 2-oxopent-4-enoate. Catalysis of the reaction: fumarylpyruvate + H2O = fumarate + pyruvate + H+. Catalysis of the reaction: 4-fumarylacetoacetate + H2O = acetoacetate + fumarate. Catalysis of the reaction: 2-hydroxy-6-oxo-(2'-aminophenyl)-hexa-2,4-dienoat + H2O = 2-aminobenzoate + cis-2-hydroxypenta-2,4-dienoate. Catalysis of the reaction: 2-hydroxy-6-oxoocta-2,4-dienoate + H2O = H+ + propanoate + cis-2-hydroxypenta-2,4-dienoate. Catalysis of the reaction: 2-hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate + H2O = cis-2-hydroxypenta-2,4-dienoate + phthalate + H+. Catalysis of the reaction: 2,6-dihydroxypseudooxynicotine + H2O = 2,6-dihydroxypyridine + 4-methylaminobutyrate. Catalysis of the reaction: 4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoate + H2O = 2-hydroxydec-2,4-diene-1,10-dioate + H+. Catalysis of the reaction: oxaloacetate + H2O = oxalate + acetate. Catalysis of the hydrolysis of any acid carbon-carbon bond in a ketonic substance, a substance containing a keto (C=O) group. Catalysis of the hydrolysis of any acid carbon-carbon bond. Catalysis of the reaction: (3E,1Z)-4,5-9,10-Diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate + H2O = (2E,4E)-2-hydroxyhexa-2,4-dienoate + 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oate + H+. Catalysis of the reaction: 2,4-dinitrocyclohexanone + OH- = 4,6-dinitrohexanoate. Catalysis of the reaction: a 3-acylpyruvate + H2O = a carboxylate + pyruvate. Catalysis of the reaction: 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate + H2O = cis-2-hydroxypenta-2,4-dienoate + isobutyrate. Catalysis of the reaction: 6-oxo-2-hydroxycyclohexane-1-carboxyl-CoA + H2O = 3-hydroxypimeloyl-CoA. Catalysis of the reaction: dihydrophloroglucinol + OH- = 3-hydroxy-5-oxohexanoate. Catalysis of the reaction: cis,cis-2-hydroxy-6-oxohept-2,4-dienoate + OH- = cis-2-hydroxypenta-2,4-dienoate + acetate. Catalysis of the reaction: 2-ketocyclohexane-1-carboxyl-CoA + H2O = pimeloyl-CoA. Catalysis of the reaction: 6-hydroxy-3-succinoylpyridine + H2O = succinic semialdehyde + 2,5-dihydroxypyridine. Catalysis of the reaction: phloretin + H2O = phloretate + phloroglucinol. Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3. Catalysis of the reaction: 4-isopropenyl-2-ketocyclohexane-1-carboxyl-CoA + H2O = 3-isopropenylpimelyl-CoA.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances
Acc: GO:0016823
Aspect: Molecular Function
Desc: Catalysis of the hydrolysis of any acid carbon-carbon bond in a ketonic substance, a substance containing a keto (C=O) group.
Proteins in PDR annotated with:
   This term: 1 [Search]
   Term or descendants: 17 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0016823 - hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances (interactive image map)
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