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View Structure Prediction Details

Protein: CG9485-PB
Organism: Drosophila melanogaster
Length: 1629 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG9485-PB.

Description E-value Query
Range		 Subject
Range
gi|109011432, gi... - gi|109011436|ref|XP_001106421.1| PREDICTED: similar to amylo-1,6-glucosidase, 4-alpha-glucanotransfe...
 1710.0 [0..91] [1621..1]

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Predicted Domain #1
Region A:
Residues: [1-68] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRYQLFRWLY GLIATVDNEP LPLQIKSEEE AFGENKKKKQ LASLENAISP GKLDSVAIRT  60
   61 VPSANANA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [69-580] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGNAGSAEIV SNQIIRRREM STMGKETESH SIPISEGQDA EHILYRLKRG SKLSVHPDAS  60
   61 LLGRKIVLYT NYPAEGQKFV RTEYRVLGWQ LSNGKQITSV MHPEAHVVDT DIRSQVELNM 120
  121 SGTYHFYFRY LERPDTGCSG ADGALYVQVE PTLHVGPPGA QKTIPLDSVR CQTVLAKLLG 180
  181 PLDTWEPKLR VAKEAGYNVI HFTPIQELGG SRSCYSLRDQ LKVNSHFAPQ KGGKISFEDV 240
  241 EKVIKKCRQE WGVASICDIV LNHTANESDW LLQHPDATYS CATCPYLRPA FLLDATFAQC 300
  301 GADIAEGSLE HVGVPAVIEQ ECHLEALKYQ LHTSYMSKVN IHELYQCDVM KYVNEFMSQV 360
  361 RTREPPKNVA NECRFQEIQL IQDPQYRRLA STINFELALE IFNAFHGDCF DEESRFRKCA 420
  421 ETLRRHLDAL NDRVRCEVQG YINYAIDNVL AGVRYERVQG DGPRVKEISE KHSVFMVYFT 480
  481 HTGTQGKSLT EIEADMYTKA GEFFMAHNGW VM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 73.69897
Match: 1j0hA
Description: Neopullulanase, central domain; Neopullulanase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity, hydrolyzing O-glycosyl compounds 4.55801959095491 bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds 4.29108420555514 bayes_pls_golite062009
hydrolase activity 3.3484406095165 bayes_pls_golite062009
glucosidase activity 1.92306554001182 bayes_pls_golite062009
catalytic activity 1.85569074294201 bayes_pls_golite062009
cation transmembrane transporter activity 1.69105818607475 bayes_pls_golite062009
alpha-amylase activity 1.42264105957213 bayes_pls_golite062009
ion transmembrane transporter activity 1.39709424453076 bayes_pls_golite062009
amylase activity 1.37652764526134 bayes_pls_golite062009
ligand-gated ion channel activity 1.05409109078129 bayes_pls_golite062009
ligand-gated channel activity 1.05409109078129 bayes_pls_golite062009
cation channel activity 1.05200514582216 bayes_pls_golite062009
gated channel activity 0.9985637228196 bayes_pls_golite062009
phosphorylase activity 0.99159540154441 bayes_pls_golite062009
ion channel activity 0.90214915215542 bayes_pls_golite062009
oxidoreductase activity 0.88505980389015 bayes_pls_golite062009
hexosaminidase activity 0.763360027922833 bayes_pls_golite062009
substrate-specific channel activity 0.7468694373149 bayes_pls_golite062009
channel activity 0.72022399139884 bayes_pls_golite062009
passive transmembrane transporter activity 0.72022399139884 bayes_pls_golite062009
carbohydrate binding 0.66542913126194 bayes_pls_golite062009
binding 0.63693798355947 bayes_pls_golite062009
voltage-gated cation channel activity 0.607543065522144 bayes_pls_golite062009
sugar binding 0.52048704356718 bayes_pls_golite062009
alpha-glucosidase activity 0.502835520523619 bayes_pls_golite062009
chitinase activity 0.500233744020165 bayes_pls_golite062009
voltage-gated channel activity 0.469037239588056 bayes_pls_golite062009
voltage-gated ion channel activity 0.432338683948607 bayes_pls_golite062009
transferase activity, transferring hexosyl groups 0.266938437560648 bayes_pls_golite062009
beta-N-acetylhexosaminidase activity 0.263065978664289 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [581-649] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GYSDPLRDFA EEQPGRANVY LKRELISWGD SVKLRFGRRP EDSPYLWQHM TEYVQTTARI  60
   61 FDGVRLDNC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 71.221849
Match: 1uokA
Description: CRYSTAL STRUCTURE OF B. CEREUS OLIGO-1,6-GLUCOSIDASE
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [650-735] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HSTPLHVAEY LLDAARKINP ELYVVAELFT NSDYTDNVFV NRLGITSLIR EALSAWDSHE  60
   61 QGRLVYRYGG VPVGGFQANS SRHEAT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [736-897] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SVAHALFLDL THDNPSPVEK RSVYDLLPSA ALVSMACCAT GSNRGYDELV PHHIHVVDEE  60
   61 RTYQEWGKGV DSKSGIMGAK RALNLLHGQL AEEGFSQVYV DQMDPNVVAV TRHSPITHQS 120
  121 VILVAHTAFG YPSPNAGPTG IRPLRFEGVL DEIILEASLT MQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [898-1102] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDKPFDRPAP FKKDPNVING FTQFQLNLQE HIPLAKSTVF QTQAYSDGNN TELNFANLRP  60
   61 GTVVAIRVSM HPGPRTSFDK LQKISAALRI GSGEEYSQLQ AIVSKLDLVA LSGALFSCDD 120
  121 EERDLGKGGT AYDIPNFGKI VYCGLQGFIS LLTEISPKND LGHPLCNNLR DGNWMMDYIS 180
  181 DRLTSYEDLK PLSAWFKATF EPLKN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [1103-1629] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IPRYLIPCYF DAIVSGVYNV LINQVNELMP DFIKNGHSFP QSLALSTLQF LSVCKSANLP  60
   61 GFSPALSPPK PPKQCVTLSA GLPHFSTGYM RCWGRDTFIA LRGSMFLTGR YNEARFIIIG 120
  121 FGQTLRHGLI PNLLDSGSKP RFNCRDAIWW WMYCIKQYVE DAPKGAEILK DKVSRIFPYD 180
  181 DADAHAPGAF DQLLFDVMQE ALQVHFQGLQ YRERNAGYEI DAHMVDQGFN NQIGIHPETG 240
  241 FVFGGNNFNC GTWMDKMGSS QKAGNKGRPS TPRDGSAVEL VGLQYAVLRF MQSLAEKEVI 300
  301 PYTGVERKGP SGEVTKWSYK EWADRIKNNF DKYFFVSESE TCSVANKKLI YKDSYGATQS 360
  361 WTDYQLRCNF PITLTVAPDL CNPQNAWRAL ERAKKYLLGP LGMKTMDPED WNYRANYDNS 420
  421 NDSTDCTVAH GANYHQGPEW VWPIGFYLRA RLIFAKKCGH LDETIAETWA ILRAHLRELQ 480
  481 TSHWRGLPEL TNDNGSYCGD SCRTQAWSVA AILEVLYDLH SLGADVA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 71.69897
Match: 2jf4A
Description: No description for 2jf4A was found.
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle