| Protein: | SMG7 |
| Organism: | Homo sapiens |
| Length: | 1137 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SMG7.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..1137] | [1..1137] |
|
|
0.0 | [3..1137] | [12..1195] |
|
|
0.0 | [1..1137] | [1..1134] |
|
|
0.0 | [19..1137] | [1..1119] |
|
|
0.0 | [19..1137] | [1..1072] |
|
|
0.0 | [1..1101] | [270..1374] |
|
Region A: Residues: [1-497] |
1 11 21 31 41 51
| | | | | |
1 MSLQSAQYLR QAEVLKADMT DSKLGPAEVW TSRQALQDLY QKMLVTDLEY ALDKKVEQDL 60
61 WNHAFKNQIT TLQGQAKNRA NPNRSEVQAN LSLFLEAASG FYTQLLQELC TVFNVDLPCR 120
121 VKSSQLGIIS NKQTHTSAIV KPQSSSCSYI CQHCLVHLGD IARYRNQTSQ AESYYRHAAQ 180
181 LVPSNGQPYN QLAILASSKG DHLTTIFYYC RSIAVKFPFP AASTNLQKAL SKALESRDEV 240
241 KTKWGVSDFI KAFIKFHGHV YLSKSLEKLS PLREKLEEQF KRLLFQKAFN SQQLVHVTVI 300
301 NLFQLHHLRD FSNETEQHTY SQDEQLCWTQ LLALFMSFLG ILCKCPLQNE SQEESYNAYP 360
361 LPAVKVSMDW LRLRPRVFQE AVVDERQYIW PWLISLLNSF HPHEEDLSSI SATPLPEEFE 420
421 LQGFLALRPS FRNLDFSKGH QGITGDKEGQ QRRIRQQRLI SIGKWIADNQ PRLIQCENEV 480
481 GKLLFITEIP ELILEDP
|
| Detection Method: |  |
| Confidence: | 1000.0 |
| Match: | 1ya0A |
| Description: | Crystal structure of the N-terminal domain of human SMG7 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.71974493738804 | bayes_pls_golite062009 |
| phosphatase activity | 2.07121787064839 | bayes_pls_golite062009 |
| phosphoric ester hydrolase activity | 2.0064822460534 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 1.93890458151007 | bayes_pls_golite062009 |
| protein binding | 1.6279032205159 | bayes_pls_golite062009 |
| phosphoprotein phosphatase activity | 1.5101001424727 | bayes_pls_golite062009 |
| protein phosphatase 2A binding | 1.46939554648762 | bayes_pls_golite062009 |
| transcription regulator activity | 1.4301086471216 | bayes_pls_golite062009 |
| nucleic acid binding | 1.22236203837379 | bayes_pls_golite062009 |
| DNA binding | 1.20537879865251 | bayes_pls_golite062009 |
| RNA binding | 1.1868411700113 | bayes_pls_golite062009 |
| signal sequence binding | 0.71760275307167 | bayes_pls_golite062009 |
| transcription factor activity | 0.565947156932776 | bayes_pls_golite062009 |
| hydrolase activity | 0.252678932946087 | bayes_pls_golite062009 |
| transcription factor binding | 0.165601865897969 | bayes_pls_golite062009 |
| protein serine/threonine phosphatase activity | 0.138767551347851 | bayes_pls_golite062009 |
|
Region A: Residues: [498-637] |
1 11 21 31 41 51
| | | | | |
1 SEAKENLILQ ETSVIESLAA DGSPGLKSVL STSRNLSNNC DTGEKPVVTF KENIKTREVN 60
61 RDQGRSFPPK EVRRDYSKGI TVTKNDGKKD NNKRKTETKK CTLEKLQETG KQNVAVQVKS 120
121 QTELRKTPVS EARKTPVTQT
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [638-869] |
1 11 21 31 41 51
| | | | | |
1 PTQASNSQFI PIHHPGAFPP LPSRPGFPPP TYVIPPPVAF SMGSGYTFPA GVSVPGTFLQ 60
61 PTAHSPAGNQ VQAGKQSHIP YSQQRPSGPG PMNQGPQQSQ PPSQQPLTSL PAQPTAQSTS 120
121 QLQVQALTQQ QQSPTKAVPA LGKSPPHHSG FQQYQQADAS KQLWNPPQVQ GPLGKIMPVK 180
181 QPYYLQTQDP IKLFEPSLQP PVMQQQPLEK KMKPFPMEPY NHNPSEVKVP EF
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [870-992] |
1 11 21 31 41 51
| | | | | |
1 YWDSSYSMAD NRSVMAQQAN IDRRGKRSPG VFRPEQDPVP RMPFEKSLLE KPSELMSHSS 60
61 SFLSLTGFSL NQERYPNNSM FNEVYGKNLT SSSKAELSPS MAPQETSLYS LFEGTPWSPS 120
121 LPA
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [993-1137] |
1 11 21 31 41 51
| | | | | |
1 SSDHSTPASQ SPHSSNPSSL PSSPPTHNHN SVPFSNFGPI GTPDNRDRRT ADRWKTDKPA 60
61 MGGFGIDYLS ATSSSESSWH QASTPSGTWT GHGPSMEDSS AVLMESLKSI WSSSMMHPGP 120
121 SALEQLLMQQ KQKQQRGQGT MNPPH
|
| Detection Method: | |
| Confidence: | 1.05 |
| Match: | 1dbgA |
| Description: | Chondroitinase B |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| catalytic activity | 0.647299603114184 | bayes_pls_golite062009 |
| hydrolase activity | 0.496523474039919 | bayes_pls_golite062009 |
