YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|119596571, gi...
Organism:	Homo sapiens
Length:	373 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|119596571, gi....

Description	E-value	Query Range	Subject Range
gi\|76689273 - gi\|76689273\|ref\|XP_881129.1\| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 1 ...	2.0E-51	[3..365]	[18..395]
gi\|13096978 - gi\|13096978\|gb\|AAH03283.1\| Poly(A) binding protein, cytoplasmic 4 [Mus musculus]	1.0E-50	[3..365]	[18..385]
gi\|73976775 - gi\|73976775\|ref\|XP_539581.2\| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 1 ...	2.0E-50	[3..365]	[18..385]
gi\|48734702 - gi\|48734702\|gb\|AAH71591.1\| PABPC4 protein [Homo sapiens]	2.0E-50	[3..365]	[18..385]
gi\|55959639, gi\|... - gi\|66267552\|gb\|AAH94755.1\| PABPC4 protein [Homo sapiens], gi\|55962217\|emb\|CAI12298.1\| poly(A) bindin... gi\|114555673 - gi\|114555673\|ref\|XP_001170937.1\| PREDICTED: poly A binding protein, cytoplasmic 4 isoform 1 [Pan tro...	3.0E-50	[3..365]	[18..385]

Back

Predicted Domain #1

Region A:
Residues: [1-86]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQLAARIRPR DLEEFFSTVG KVRDVRMISD RNSRRSKGIA YVEFVDVSSV PLAIGLTGQR  60
   61 VLGVPIIVQA SQAEKNRAAA MANNLQ

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	4.82
Match:	2dgsA
Description:	No description for 2dgsA was found.

Predicted Domain #2

Region A:
Residues: [87-176]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KGSAGPMRLY VGSLHFNITE DMLRGIFEPF GRIESIQLMM DSETGRSKGY GFITFSDSEC  60
   61 AKKALEQLNG FELAGRPMKV GHVTERTDAS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	22.522879
Match:	2jrsA
Description:	No description for 2jrsA was found.

Predicted Domain #3

Region A:
Residues: [177-239]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SASSFLDSDE LERTGIDLGT TGRLQLMARL AEGTGLQIPP AAQQALQMSG SLAFGAVAEF  60
   61 SFV

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [240-373]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IDLQTRLSQQ TEASALAAAA SVQPLATQCF QLSNMFNPQT EEEVGWDTEI KDDVIEECNK  60
   61 HGGVIHIYVD KNSAQGNVYV KCPSIAAAIA AVNALHGRWF AGKMITAAYV PLPTYHNLFP 120
  121 DSMTATQLLV PSRR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	5.30103
Match:	2ditA
Description:	No description for 2ditA was found.

Predicted functions:

Term	Confidence	Notes
RNA binding	6.73097473547076	bayes_pls_golite062009
	6.62953239642182	bayes_pls_golite062009
mRNA binding	5.29759606920196	bayes_pls_golite062009
nucleic acid binding	4.92126426323641	bayes_pls_golite062009
binding	3.64400841800969	bayes_pls_golite062009
snRNA binding	3.28448936696877	bayes_pls_golite062009
poly-pyrimidine tract binding	3.11990160533699	bayes_pls_golite062009
single-stranded RNA binding	2.93798024346416	bayes_pls_golite062009
U1 snRNA binding	2.26303528058407	bayes_pls_golite062009
transcription regulator activity	1.92450390013691	bayes_pls_golite062009
DNA binding	1.8021593476478	bayes_pls_golite062009
structural molecule activity	1.29928829870122	bayes_pls_golite062009
transcription factor activity	1.15127506309683	bayes_pls_golite062009
protein binding	1.12215421354121	bayes_pls_golite062009
mRNA 3'-UTR binding	0.591700155096213	bayes_pls_golite062009
sequence-specific DNA binding	0.383589644462932	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: