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View Structure Prediction Details

Protein: gi|119596571, gi...
Organism: Homo sapiens
Length: 373 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|119596571, gi....

Description E-value Query
Range
Subject
Range
gi|76689273 - gi|76689273|ref|XP_881129.1| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 1 ...
2.0E-51 [3..365] [18..395]
gi|13096978 - gi|13096978|gb|AAH03283.1| Poly(A) binding protein, cytoplasmic 4 [Mus musculus]
1.0E-50 [3..365] [18..385]
gi|73976775 - gi|73976775|ref|XP_539581.2| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 1 ...
2.0E-50 [3..365] [18..385]
gi|48734702 - gi|48734702|gb|AAH71591.1| PABPC4 protein [Homo sapiens]
2.0E-50 [3..365] [18..385]
gi|55959639, gi|... - gi|66267552|gb|AAH94755.1| PABPC4 protein [Homo sapiens], gi|55962217|emb|CAI12298.1| poly(A) bindin...
gi|114555673 - gi|114555673|ref|XP_001170937.1| PREDICTED: poly A binding protein, cytoplasmic 4 isoform 1 [Pan tro...
3.0E-50 [3..365] [18..385]

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Predicted Domain #1
Region A:
Residues: [1-86]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQLAARIRPR DLEEFFSTVG KVRDVRMISD RNSRRSKGIA YVEFVDVSSV PLAIGLTGQR  60
   61 VLGVPIIVQA SQAEKNRAAA MANNLQ

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.82
Match: 2dgsA
Description: No description for 2dgsA was found.

Predicted Domain #2
Region A:
Residues: [87-176]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KGSAGPMRLY VGSLHFNITE DMLRGIFEPF GRIESIQLMM DSETGRSKGY GFITFSDSEC  60
   61 AKKALEQLNG FELAGRPMKV GHVTERTDAS 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.522879
Match: 2jrsA
Description: No description for 2jrsA was found.

Predicted Domain #3
Region A:
Residues: [177-239]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SASSFLDSDE LERTGIDLGT TGRLQLMARL AEGTGLQIPP AAQQALQMSG SLAFGAVAEF  60
   61 SFV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [240-373]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IDLQTRLSQQ TEASALAAAA SVQPLATQCF QLSNMFNPQT EEEVGWDTEI KDDVIEECNK  60
   61 HGGVIHIYVD KNSAQGNVYV KCPSIAAAIA AVNALHGRWF AGKMITAAYV PLPTYHNLFP 120
  121 DSMTATQLLV PSRR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.30103
Match: 2ditA
Description: No description for 2ditA was found.

Predicted functions:

Term Confidence Notes
RNA binding 6.73097473547076 bayes_pls_golite062009
6.62953239642182 bayes_pls_golite062009
mRNA binding 5.29759606920196 bayes_pls_golite062009
nucleic acid binding 4.92126426323641 bayes_pls_golite062009
binding 3.64400841800969 bayes_pls_golite062009
snRNA binding 3.28448936696877 bayes_pls_golite062009
poly-pyrimidine tract binding 3.11990160533699 bayes_pls_golite062009
single-stranded RNA binding 2.93798024346416 bayes_pls_golite062009
U1 snRNA binding 2.26303528058407 bayes_pls_golite062009
transcription regulator activity 1.92450390013691 bayes_pls_golite062009
DNA binding 1.8021593476478 bayes_pls_golite062009
structural molecule activity 1.29928829870122 bayes_pls_golite062009
transcription factor activity 1.15127506309683 bayes_pls_golite062009
protein binding 1.12215421354121 bayes_pls_golite062009
mRNA 3'-UTR binding 0.591700155096213 bayes_pls_golite062009
sequence-specific DNA binding 0.383589644462932 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle