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View Structure Prediction Details

Protein: UBE2J2
Organism: Homo sapiens
Length: 259 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UBE2J2.

Description E-value Query
Range
Subject
Range
UBE2J2 - ubiquitin-conjugating enzyme E2, J2 (UBC6 homolog, yeast)
2.0E-72 [1..259] [1..259]
gi|73956479 - gi|73956479|ref|XP_848334.1| PREDICTED: similar to Ubiquitin-conjugating enzyme E2 J2 (Non-canonical...
2.0E-70 [1..259] [1..259]
UB2J2_MOUSE - Ubiquitin-conjugating enzyme E2 J2 OS=Mus musculus GN=Ube2j2 PE=1 SV=1
2.0E-69 [1..259] [1..259]
gi|56090425, gi|... - gi|56090425|ref|NP_001007656.1| ubiquitin-conjugating enzyme E2, J2 [Rattus norvegicus], gi|50925701...
3.0E-69 [1..259] [1..259]
UB2J2_BOVIN - Ubiquitin-conjugating enzyme E2 J2 OS=Bos taurus GN=UBE2J2 PE=2 SV=1
7.0E-69 [1..259] [1..259]

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Predicted Domain #1
Region A:
Residues: [1-259]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSTSSKRAP TTATQRLKQD YLRIKKDPVP YICAEPLPSN ILEWHYVVRG PEMTPYEGGY  60
   61 YHGKLIFPRE FPFKPPSIYM ITPNGRFKCN TRLCLSITDF HPDTWNPAWS VSTILTGLLS 120
  121 FMVEKGPTLG SIETSDFTKR QLAVQSLAFN LKDKVFCELF PEVVEEIKQK QKAQDELSSR 180
  181 PQTLPLPDVV PDGETHLVQN GIQLLNGHAP GAVPNLAGLQ QANRHHGLLG GALANLFVIV 240
  241 GFAAFAYTVK YVLRSIAQE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.39794
Match: 2f4wA
Description: Human ubiquitin-conjugating enzyme E2 J2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ubiquitin-protein ligase activity 7.07009148420636 bayes_pls_golite062009
small conjugating protein ligase activity 7.03976510657099 bayes_pls_golite062009
acid-amino acid ligase activity 6.00007452476109 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 5.06177413452771 bayes_pls_golite062009
ligase activity 1.88059319399119 bayes_pls_golite062009
binding 1.60562701414102 bayes_pls_golite062009
protein binding 0.933717013010244 bayes_pls_golite062009
catalytic activity 0.891402822028799 bayes_pls_golite062009
SUMO ligase activity 0.843488104298821 bayes_pls_golite062009
NEDD8 ligase activity 0.715654744941217 bayes_pls_golite062009
nucleic acid binding 0.709850784309504 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.58835335751383 bayes_pls_golite062009
DNA binding 0.535532147708899 bayes_pls_golite062009
kinase activity 0.519703305315987 bayes_pls_golite062009
protein kinase activity 0.443948654247666 bayes_pls_golite062009
transcription regulator activity 0.407883318397228 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.373779304908933 bayes_pls_golite062009
protein serine/threonine kinase activity 0.182854082413338 bayes_pls_golite062009
transferase activity 0.0984525836903841 bayes_pls_golite062009

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