YRC Public Data Repository - Protein Structure Prediction

Protein:	YPDF_ECOLI
Organism:	Escherichia coli
Length:	361 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YPDF_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|56380788, gi\|... - gi\|56420946\|ref\|YP_148264.1\| Xaa-Pro dipeptidase [Geobacillus kaustophilus HTA426], gi\|56380788\|dbj\|...	351.0	[0..1]	[358..1]
gi\|89159173, gi\|... - gi\|89211210\|ref\|ZP_01189584.1\| Peptidase M24 [Halothermothrix orenii H 168], gi\|89159173\|gb\|EAR78847...	347.0	[0..1]	[356..17]
gi\|23099351, gi\|... - gi\|23099351\|ref\|NP_692817.1\| Xaa-Pro dipeptidase [Oceanobacillus iheyensis HTE831], gi\|22777580\|dbj\|...	344.0	[0..1]	[356..1]
gi\|89200835, gi\|... - gi\|89200835\|ref\|ZP_01179585.1\| Peptidase M24 [Bacillus cereus subsp. cytotoxis NVH 391-98], gi\|89151...	342.0	[0..1]	[358..1]
gi\|51856692, gi\|... - gi\|51893003\|ref\|YP_075694.1\| Xaa-Pro dipeptidase [Symbiobacterium thermophilum IAM 14863], gi\|518566...	341.0	[0..15]	[358..17]
gi\|42783317, gi\|... - gi\|42783317\|ref\|NP_980564.1\| proline dipeptidase [Bacillus cereus ATCC 10987], gi\|42739245\|gb\|AAS431...	341.0	[0..1]	[358..1]
gi\|51974768, gi\|... - gi\|52141299\|ref\|YP_085531.1\| proline dipeptidase, Xaa-Pro dipeptidase [Bacillus cereus E33L], gi\|519...	341.0	[0..1]	[358..1]
gi\|65321584, gi\|... - gi\|65321584\|ref\|ZP_00394543.1\| COG0006: Xaa-Pro aminopeptidase [Bacillus anthracis str. A2012], ref\|... gi\|167638703, gi... - gi\|167638703\|ref\|ZP_02396979.1\| X-Pro dipeptidase [Bacillus anthracis str. A0193], gi\|167513551\|gb\|E... gi\|170687449, gi... - gi\|170687449\|ref\|ZP_02878666.1\| X-Pro dipeptidase [Bacillus anthracis str. A0465], gi\|170668644\|gb\|E... gi\|170709036, gi... - gi\|170709036\|ref\|ZP_02899466.1\| X-Pro dipeptidase [Bacillus anthracis str. A0389], gi\|170126063\|gb\|E... gi\|177654785, gi... - gi\|177654785\|ref\|ZP_02936542.1\| X-Pro dipeptidase [Bacillus anthracis str. A0174], gi\|172080446\|gb\|E... gi\|190565975, gi... - gi\|190565975\|ref\|ZP_03018894.1\| X-Pro dipeptidase [Bacillus anthracis Tsiankovskii-I], gi\|190562894\|... gi\|49187100, gi\|... - gi\|49187100\|ref\|YP_030352.1\| proline dipeptidase [Bacillus anthracis str. Sterne], gi\|49181027\|gb\|AA... gi\|196035035, gi... - gi\|196035035\|ref\|ZP_03102442.1\| X-Pro dipeptidase [Bacillus cereus W], gi\|195992574\|gb\|EDX56535.1\| X... gi\|47504863, gi\|... - gi\|47529715\|ref\|YP_021064.1\| proline dipeptidase [Bacillus anthracis str. 'Ames Ancestor'], gi\|47504... gi\|196041542, gi... - gi\|196041542\|ref\|ZP_03108834.1\| X-Pro dipeptidase [Bacillus cereus NVH0597-99], gi\|196027530\|gb\|EDX6... gi\|30258918, gi\|... - gi\|30264273\|ref\|NP_846650.1\| proline dipeptidase [Bacillus anthracis str. Ames], gi\|30258918\|gb\|AAP2... gi\|218538560, gi... - gi\|218905334\|ref\|YP_002453168.1\| X-Pro dipeptidase [Bacillus cereus AH820], gi\|218538560\|gb\|ACK90958... gi\|165872969, gi... - gi\|165872969\|ref\|ZP_02217591.1\| X-Pro dipeptidase [Bacillus anthracis str. A0488], gi\|164711252\|gb\|E... gi\|254757889 - gi\|254757889\|ref\|ZP_05209916.1\| X-Pro dipeptidase [Bacillus anthracis str. Australia 94] gi\|254754018 - gi\|254754018\|ref\|ZP_05206053.1\| X-Pro dipeptidase [Bacillus anthracis str. Vollum] gi\|254736310 - gi\|254736310\|ref\|ZP_05194016.1\| X-Pro dipeptidase [Bacillus anthracis str. Western North America USA... gi\|254721796 - gi\|254721796\|ref\|ZP_05183585.1\| X-Pro dipeptidase [Bacillus anthracis str. A1055] gi\|254683962 - gi\|254683962\|ref\|ZP_05147822.1\| X-Pro dipeptidase [Bacillus anthracis str. CNEVA-9066] gi\|229603557, gi... - gi\|229603557\|ref\|YP_002868491.1\| Xaa-Pro dipeptidase [Bacillus anthracis str. A0248], gi\|229267965\|g... gi\|228597067, gi... - gi\|229186440\|ref\|ZP_04313604.1\| Uncharacterized peptidase yqhT [Bacillus cereus BGSC 6E1], gi\|228597... gi\|229123717, gi... - gi\|229123717\|ref\|ZP_04252912.1\| Uncharacterized peptidase yqhT [Bacillus cereus 95/8201], gi\|2286598... gi\|229093256, gi... - gi\|229093256\|ref\|ZP_04224374.1\| Uncharacterized peptidase yqhT [Bacillus cereus Rock3-42], gi\|228690... gi\|228947914, gi... - gi\|228947914\|ref\|ZP_04110201.1\| Uncharacterized peptidase yqhT [Bacillus thuringiensis serovar monte... gi\|228935522, gi... - gi\|228935522\|ref\|ZP_04098339.1\| Uncharacterized peptidase yqhT [Bacillus thuringiensis serovar andal... gi\|228929243, gi... - gi\|228929243\|ref\|ZP_04092270.1\| Uncharacterized peptidase yqhT [Bacillus thuringiensis serovar pondi... gi\|227816973, gi... - gi\|227816973\|ref\|YP_002816982.1\| X-Pro dipeptidase [Bacillus anthracis str. CDC 684], gi\|227002740\|g...	340.0	[0..1]	[358..1]
gi\|229135021, gi... - gi\|229135021\|ref\|ZP_04263826.1\| Uncharacterized peptidase yqhT [Bacillus cereus BDRD-ST196], gi\|2286... gi\|163941957, gi... - gi\|89207038\|ref\|ZP_01185587.1\| Peptidase M24 [Bacillus weihenstephanensis KBAB4], gi\|89155067\|gb\|EAR...	339.0	[0..1]	[358..1]
gi\|69244731, gi\|... - gi\|69244731\|ref\|ZP_00602995.1\| Peptidase M24 [Enterococcus faecium DO], gi\|68196322\|gb\|EAN10751.1\| P... gi\|48826218 - ref\|ZP_00287443.1\| COG0006: Xaa-Pro aminopeptidase [Enterococcus faecium]	339.0	[0..1]	[358..2]

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Predicted Domain #1

Region A:
Residues: [1-361]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTLLASLRDW LKAQQLDAVL LSSRQNKQPH LGISTGSGYV VISRESAHIL VDSRYYVEVE  60
   61 ARAQGYQLHL LDATNTLTTI VNQIIADEQL QTLGFEGQQV SWETAHRWQS ELNAKLVSAT 120
  121 PDVLRQIKTP EEVEKIRLAC GIADRGAEHI RRFIQAGMSE REIAAELEWF MRQQGAEKAS 180
  181 FDTIVASGWR GALPHGKASD KIVAAGEFVT LDFGALYQGY CSDMTRTLLV NGEGVSAESH 240
  241 LLFNVYQIVL QAQLAAISAI RPGVRCQQVD DAARRVITEA GYGDYFGHNT GHAIGIEVHE 300
  301 DPRFSPRDTT TLQPGMLLTV EPGIYLPGQG GVRIEDVVLV TPQGAEVLYA MPKTVLLTGE 360
  361 A

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	85.0
Match:	1pv9A
Description:	Prolidase from Pyrococcus furiosus
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
peptidase activity	2.76723095667188	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	2.32675126054468	bayes_pls_golite062009
hydrolase activity	1.32640177567297	bayes_pls_golite062009
exopeptidase activity	1.11241584879462	bayes_pls_golite062009
metallopeptidase activity	1.0610925051469	bayes_pls_golite062009
aminopeptidase activity	0.53115813873012	bayes_pls_golite062009
catalytic activity	0.51899181055614	bayes_pls_golite062009
metalloexopeptidase activity	0.0416763295703397	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: