| Protein: | TPP2 |
| Organism: | Homo sapiens |
| Length: | 1249 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TPP2.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..1249] | [1..1249] |
|
|
0.0 | [1..1249] | [1..1249] |
|
|
0.0 | [1..1249] | [1..1249] |
|
|
0.0 | [1..1249] | [1..1249] |
|
|
0.0 | [1..1249] | [1..1249] |
|
Region A: Residues: [1-518] |
1 11 21 31 41 51
| | | | | |
1 MATAATEEPF PFHGLLPKKE TGAASFLCRY PEYDGRGVLI AVLDTGVDPG APGMQVTTDG 60
61 KPKIVDIIDT TGSGDVNTAT EVEPKDGEIV GLSGRVLKIP ASWTNPSGKY HIGIKNGYDF 120
121 YPKALKERIQ KERKEKIWDP VHRVALAEAC RKQEEFDVAN NGSSQANKLI KEELQSQVEL 180
181 LNSFEKKYSD PGPVYDCLVW HDGEVWRACI DSNEDGDLSK STVLRNYKEA QEYGSFGTAE 240
241 MLNYSVNIYD DGNLLSIVTS GGAHGTHVAS IAAGHFPEEP ERNGVAPGAQ ILSIKIGDTR 300
301 LSTMETGTGL IRAMIEVINH KCDLVNYSYG EATHWPNSGR ICEVINEAVW KHNIIYVSSA 360
361 GNNGPCLSTV GCPGGTTSSV IGVGAYVSPD MMVAEYSLRE KLPANQYTWS SRGPSADGAL 420
421 GVSISAPGGA IASVPNWTLR GTQLMNGTSM SSPNACGGIA LILSGLKANN IDYTVHSVRR 480
481 ALENTAVKAD NIEVFAQGHG IIQVDKAYDY LVQNTSFA
|
| Detection Method: |  |
| Confidence: | 6.69897 |
| Match: | 1r6vA |
| Description: | Crystal structure of fervidolysin from Fervidobacterium pennivorans, a keratinolytic enzyme related to subtilisin |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| peptidase activity | 3.80926331563638 | bayes_pls_golite062009 |
| peptidase activity, acting on L-amino acid peptides | 3.44676270522493 | bayes_pls_golite062009 |
| endopeptidase activity | 2.34981838083066 | bayes_pls_golite062009 |
| hydrolase activity | 1.91868221854892 | bayes_pls_golite062009 |
| serine hydrolase activity | 1.90036575189745 | bayes_pls_golite062009 |
| serine-type peptidase activity | 1.89198766955068 | bayes_pls_golite062009 |
| serine-type endopeptidase activity | 1.23150012549143 | bayes_pls_golite062009 |
| catalytic activity | 0.597535457699629 | bayes_pls_golite062009 |
| binding | 0.38308887521311 | bayes_pls_golite062009 |
|
Region A: Residues: [519-644] |
1 11 21 31 41 51
| | | | | |
1 NKLGFTVTVG NNRGIYLRDP VQVAAPSDHG VGIEPVFPEN TENSEKISLQ LHLALTSNSS 60
61 WVQCPSHLEL MNQCRHINIR VDPRGLREGL HYTEVCGYDI ASPNAGPLFR VPITAVIAAK 120
121 VNESSH
|
| Detection Method: | |
| Confidence: | 61.69897 |
| Match: | 1p8jA |
| Description: | Furin, C-terminal domain; Furin, N-terminal domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| peptidase activity | 3.80926331563638 | bayes_pls_golite062009 |
| peptidase activity, acting on L-amino acid peptides | 3.44676270522493 | bayes_pls_golite062009 |
| endopeptidase activity | 2.34981838083066 | bayes_pls_golite062009 |
| hydrolase activity | 1.91868221854892 | bayes_pls_golite062009 |
| serine hydrolase activity | 1.90036575189745 | bayes_pls_golite062009 |
| serine-type peptidase activity | 1.89198766955068 | bayes_pls_golite062009 |
| serine-type endopeptidase activity | 1.23150012549143 | bayes_pls_golite062009 |
| catalytic activity | 0.597535457699629 | bayes_pls_golite062009 |
| binding | 0.38308887521311 | bayes_pls_golite062009 |
|
Region A: Residues: [645-729] |
1 11 21 31 41 51
| | | | | |
1 YDLAFTDVHF KPGQIRRHFI EVPEGATWAE VTVCSCSSEV SAKFVLHAVQ LVKQRAYRSH 60
61 EFYKFCSLPE KGTLTEAFPV LGGKA
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [730-1249] |
1 11 21 31 41 51
| | | | | |
1 IEFCIARWWA SLSDVNIDYT ISFHGIVCTA PQLNIHASEG INRFDVQSSL KYEDLAPCIT 60
61 LKNWVQTLRP VSAKTKPLGS RDVLPNNRQL YEMVLTYNFH QPKSGEVTPS CPLLCELLYE 120
121 SEFDSQLWII FDQNKRQMGS GDAYPHQYSL KLEKGDYTIR LQIRHEQISD LERLKDLPFI 180
181 VSHRLSNTLS LDIHENHSFA LLGKKKSSNL TLPPKYNQPF FVTSLPDDKI PKGAGPGCYL 240
241 AGSLTLSKTE LGKKADVIPV HYYLIPPPTK TKNGSKDKEK DSEKEKDLKE EFTEALRDLK 300
301 IQWMTKLDSS DIYNELKETY PNYLPLYVAR LHQLDAEKER MKRLNEIVDA ANAVISHIDQ 360
361 TALAVYIAMK TDPRPDAATI KNDMDKQKST LVDALCRKGC ALADHLLHTQ AQDGAISTDA 420
421 EGKEEEGESP LDSLAETFWE TTKWTDLFDN KVLTFAYKHA LVNKMYGRGL KFATKLVEEK 480
481 PTKENWKNCI QLMKLLGWTH CASFTENWLP IMYPPDYCVF
|
| Detection Method: | |
| Confidence: | 2.2 |
| Match: | 2gw1A |
| Description: | No description for 2gw1A was found. |
