| Protein: | NPC2_CANLF |
| Organism: | Canis lupus familiaris |
| Length: | 149 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NPC2_CANLF.
| Description | E-value | Query Range |
Subject Range |
|
|
186.0 | [0..1] | [149..1] |
|
|
173.0 | [0..1] | [149..1] |
|
|
169.0 | [0..14] | [149..14] |
|
|
169.0 | [0..1] | [149..1] |
|
|
159.0 | [0..2] | [149..1] |
|
Region A: Residues: [1-149] |
1 11 21 31 41 51
| | | | | |
1 MRLLVAAFLL LALGDLGPGG AVHFKDCGSA VGVIKELNVN PCPAQPCKLH KGQSYSVNVT 60
61 FTSNIPSQSS KAVVHGIVLG VAVPFPIPEA DGCKSGINCP IQKDKTYSYL NKLPVKNEYP 120
121 SIKLVVQWML LGDNNQHLFC WEIPVQIEG
|
| Detection Method: |  |
| Confidence: | 41.0 |
| Match: | 1nepA |
| Description: | Epididymal secretory protein E1 (Niemann-Pick C2 protein) |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.45696367038333 | bayes_pls_golite062009 |
| ligand-gated channel activity | 1.76150217842113 | bayes_pls_golite062009 |
| ligand-gated ion channel activity | 1.76150217842113 | bayes_pls_golite062009 |
| protein binding | 1.40303524581236 | bayes_pls_golite062009 |
| cholesterol binding | 1.06647503454536 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.929966017205863 | bayes_pls_golite062009 |
| potassium channel activity | 0.871728492941793 | bayes_pls_golite062009 |
| voltage-gated cation channel activity | 0.848303301157398 | bayes_pls_golite062009 |
| voltage-gated ion channel activity | 0.829939555243379 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.829140804686535 | bayes_pls_golite062009 |
| voltage-gated channel activity | 0.820413268771765 | bayes_pls_golite062009 |
| channel activity | 0.796075411518814 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 0.796075411518814 | bayes_pls_golite062009 |
| substrate-specific channel activity | 0.790863065462458 | bayes_pls_golite062009 |
| voltage-gated potassium channel activity | 0.787347074261486 | bayes_pls_golite062009 |
| cation channel activity | 0.770955130885998 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 0.760234877475175 | bayes_pls_golite062009 |
| ion channel activity | 0.743051345681968 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 0.735623329949285 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 0.698762820554681 | bayes_pls_golite062009 |
| hydrolase activity | 0.62707426744686 | bayes_pls_golite062009 |
| gated channel activity | 0.62499749903999 | bayes_pls_golite062009 |
| inward rectifier potassium channel activity | 0.43450134854604 | bayes_pls_golite062009 |
| sterol binding | 0.396392013320299 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 0.20266751601478 | bayes_pls_golite062009 |
| receptor binding | 0.0582281681682861 | bayes_pls_golite062009 |
