YRC Public Data Repository - Protein Structure Prediction

Protein:	SO1346
Organism:	Shewanella oneidensis
Length:	596 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SO1346.

Description	E-value	Query Range	Subject Range
LEPA_SHESA - Elongation factor 4 OS=Shewanella sp. (strain ANA-3) GN=lepA PE=3 SV=1	617.0	[0..1]	[596..1]
LEPA_SHESR - Elongation factor 4 OS=Shewanella sp. (strain MR-7) GN=lepA PE=3 SV=1 LEPA_SHESM - Elongation factor 4 OS=Shewanella sp. (strain MR-4) GN=lepA PE=3 SV=1	615.0	[0..1]	[596..1]
LEPA_GEOKA - Elongation factor 4 OS=Geobacillus kaustophilus GN=lepA PE=3 SV=1 LEPA_GEOKA - Elongation factor 4 OS=Geobacillus kaustophilus (strain HTA426) GN=lepA PE=3 SV=1	613.0	[0..2]	[596..11]
LEPA_MAGSA - Elongation factor 4 OS=Magnetospirillum magneticum (strain AMB-1 / ATCC 700264) GN=lepA PE=3 SV=1	612.0	[0..1]	[596..4]
LEPA_MOOTA - Elongation factor 4 OS=Moorella thermoacetica (strain ATCC 39073) GN=lepA PE=3 SV=1	612.0	[0..2]	[593..6]
LEPA_BACC1 - Elongation factor 4 OS=Bacillus cereus (strain ATCC 10987 / NRS 248) GN=lepA PE=3 SV=1 gi\|229198447, gi... - gi\|229198447\|ref\|ZP_04325151.1\| GTP-binding protein lepA [Bacillus cereus m1293], gi\|228584950\|gb\|EE...	611.0	[0..3]	[596..12]
LEPA_BACHD - Elongation factor 4 OS=Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 /... LEPA_BACHD - Elongation factor 4 OS=Bacillus halodurans GN=lepA PE=3 SV=1	611.0	[0..3]	[596..12]
gi\|229157933, gi... - gi\|229157933\|ref\|ZP_04286006.1\| GTP-binding protein lepA [Bacillus cereus ATCC 4342], gi\|228625541\|g... gi\|228987570, gi... - gi\|228987570\|ref\|ZP_04147688.1\| GTP-binding protein lepA [Bacillus thuringiensis serovar tochigiensi... gi\|47553986, gi\|... - gi\|47569315\|ref\|ZP_00239999.1\| GTP-binding protein LepA [Bacillus cereus G9241], gi\|47553986\|gb\|EAL1...	611.0	[0..3]	[596..12]
gi\|254757772 - gi\|254757772\|ref\|ZP_05209799.1\| GTP-binding protein LepA [Bacillus anthracis str. Australia 94] gi\|190562059, gi... - gi\|190567068\|ref\|ZP_03019984.1\| GTP-binding protein LepA [Bacillus anthracis Tsiankovskii-I], gi\|190... gi\|254750900 - gi\|254750900\|ref\|ZP_05202939.1\| GTP-binding protein LepA [Bacillus anthracis str. Vollum] gi\|172081533, gi... - gi\|177653251\|ref\|ZP_02935503.1\| GTP-binding protein LepA [Bacillus anthracis str. A0174], gi\|1720815... gi\|254741462 - gi\|254741462\|ref\|ZP_05199149.1\| GTP-binding protein LepA [Bacillus anthracis str. Kruger B] gi\|170707378, gi... - gi\|170707378\|ref\|ZP_02897832.1\| GTP-binding protein LepA [Bacillus anthracis str. A0389], gi\|1701276... gi\|170668645, gi... - gi\|170687450\|ref\|ZP_02878667.1\| GTP-binding protein LepA [Bacillus anthracis str. A0465], gi\|1706686... gi\|167513441, gi... - gi\|167638593\|ref\|ZP_02396869.1\| GTP-binding protein LepA [Bacillus anthracis str. A0193], gi\|1675134... gi\|167634498, gi... - gi\|167634498\|ref\|ZP_02392818.1\| GTP-binding protein LepA [Bacillus anthracis str. A0442], gi\|1675299... gi\|49181141, gi\|... - gi\|49187214\|ref\|YP_030466.1\| GTP-binding protein LepA [Bacillus anthracis str. Sterne], gi\|49181141\|... gi\|165872104, gi... - gi\|165872104\|ref\|ZP_02216744.1\| GTP-binding protein LepA [Bacillus anthracis str. A0488], gi\|1647122... gi\|254736424 - gi\|254736424\|ref\|ZP_05194130.1\| GTP-binding protein LepA [Bacillus anthracis str. Western North Amer... gi\|254721910 - gi\|254721910\|ref\|ZP_05183699.1\| GTP-binding protein LepA [Bacillus anthracis str. A1055] gi\|254684076 - gi\|254684076\|ref\|ZP_05147936.1\| GTP-binding protein LepA [Bacillus anthracis str. CNEVA-9066] LEPA_BACAC - Elongation factor 4 OS=Bacillus anthracis (strain CDC 684 / NRRL 3495) GN=lepA PE=3 SV=1	611.0	[0..3]	[596..12]
LEPA_BACAH - Elongation factor 4 OS=Bacillus thuringiensis (strain Al Hakam) GN=lepA PE=3 SV=1 gi\|228596818, gi... - gi\|229186559\|ref\|ZP_04313720.1\| GTP-binding protein lepA [Bacillus cereus BGSC 6E1], gi\|228596818\|gb... gi\|196024413, gi... - gi\|196044925\|ref\|ZP_03112159.1\| GTP-binding protein LepA [Bacillus cereus 03BB108], gi\|196024413\|gb\|... LEPA_BACCZ - Elongation factor 4 OS=Bacillus cereus (strain ZK / E33L) GN=lepA PE=3 SV=1 LEPA_BACHK - Elongation factor 4 OS=Bacillus thuringiensis subsp. konkukian GN=lepA PE=3 SV=1 LEPA_BACC3 - Elongation factor 4 OS=Bacillus cereus (strain 03BB102) GN=lepA PE=3 SV=1 gi\|196039360, gi... - gi\|196039360\|ref\|ZP_03106666.1\| GTP-binding protein LepA [Bacillus cereus NVH0597-99], gi\|196029987\|... LEPA_BACHK - Elongation factor 4 OS=Bacillus thuringiensis subsp. konkukian (strain 97-27) GN=lepA PE=3 SV=1	610.0	[0..3]	[596..12]

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Predicted Domain #1

Region A:
Residues: [1-596]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKHIRNFSII AHIDHGKSTL SDRLIQVCGG LSDREMDAQV LDSMDLERER GITIKAQSVT  60
   61 LEYKAKNGEI YQLNFIDTPG HVDFSYEVSR SLAACEGALL VVDAGQGVEA QTLANCYTAL 120
  121 DMNLDVVPIL NKIDLPQADP ERVAAEIEDI VGIDAMNAVR CSAKTGVGID DVLEVIVEQI 180
  181 PPPEGNPDAP LQALIIDSWF DSYLGVVSLV RIKHGVLKKG DKFKVMSTGQ NHTADRVGIF 240
  241 TPKQTDKTEL KTGEVGFVIA GIKEIHGAPV GDTLTLAKNG ADKPLPGFKK VKPQVYAGVF 300
  301 PISTDEYENF RDALNKLSLN DASLFFEPES SSALGFGFRI GYLGLLHMEI IQERLEREYD 360
  361 LDLITTAPTV VYEVLMTSGE TIYVDNPADL PAINNIEEMR EPIVEANILV PKEYLGNVIT 420
  421 LCIEKRGTQV NMVYHGNQVA VTYHLPMAEV VMDFFDRLKS TSRGYASLEY NFIRFDPADM 480
  481 VRLDILINGD RVDALAMIIH RSNIRHRGLA LVEKMKELIP RQMFDIAIQA AVGSQIIARS 540
  541 TVKALRKDVT AKCYGGDVSR KKKLLNKQKE GKKRMKQVGN VEVPQEAFLA VLKLNE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	101.0
Match:	1efgA
Description:	Elongation factor G (EF-G), domain II; Elongation factor G (EF-G), N-terminal (G) domain; Elongation factor G (EF-G), domain IV; Elongation factor G (EF-G)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
structural constituent of ribosome	6.48160314495408	bayes_pls_golite062009
structural molecule activity	5.89785955477588	bayes_pls_golite062009
peptidyltransferase activity	2.36235718442873	bayes_pls_golite062009
translation elongation factor activity	1.78840251801545	bayes_pls_golite062009
mRNA binding	1.64128426760439	bayes_pls_golite062009
translation release factor activity	1.47279606301067	bayes_pls_golite062009
translation termination factor activity	1.47162484856171	bayes_pls_golite062009
RNA binding	1.40868766468494	bayes_pls_golite062009
transcription regulator activity	1.30900892230008	bayes_pls_golite062009
protein binding	1.24158964059466	bayes_pls_golite062009
nucleic acid binding	1.17107716081138	bayes_pls_golite062009
binding	1.0709940954148	bayes_pls_golite062009
DNA binding	0.911272650085046	bayes_pls_golite062009
catalytic activity	0.878454819018611	bayes_pls_golite062009
motor activity	0.61636596887462	bayes_pls_golite062009
transcription activator activity	0.491297187941564	bayes_pls_golite062009
RNA helicase activity	0.2302541318658	bayes_pls_golite062009
ribonuclease activity	0.19921800066954	bayes_pls_golite062009
sequence-specific DNA binding	0.180372638853914	bayes_pls_golite062009
general RNA polymerase II transcription factor activity	0.0716139935283535	bayes_pls_golite062009
transcription factor activity	0.0612932659603008	bayes_pls_golite062009
helicase activity	0.0450969969658499	bayes_pls_golite062009
cytoskeletal protein binding	0.0272673919333979	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	6.9430052008157E-5	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: