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View Structure Prediction Details

Protein: dpy-31
Organism: Caenorhabditis elegans
Length: 529 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dpy-31.

Description E-value Query
Range
Subject
Range
gi|7506745 - gi|7506745|pir||T16761 hypothetical protein R151.5 - Caenorhabditis elegans
424.0 [0..1] [517..1]

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Predicted Domain #1
Region A:
Residues: [1-85]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHKIFIIFGL LSLCAAHSLR DLSNKDEEDP PSSAPGVRKR RMMSEEDQKT VDYYMDKLNK  60
   61 LADEKHPEEI ERHKNPELVA WDRKR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [86-229]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSVLNPEEQG KFFQGDIVLY PEQAKALYEQ ALTEGKTRVK RKFIGSNLRR WDASRPIIYA  60
   61 FDGSHTQREQ RIIELALEHW HNITCLNFQR NDQANSGNRI VFTDVDGCAS NVGRHPLGEE 120
  121 QLVSLAPECI RLGVIAHEVA HALG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.0
Match: 1astA
Description: STRUCTURE OF ASTACIN AND IMPLICATIONS FOR ACTIVATION OF ASTACINS AND ZINC-LIGATION OF COLLAGENASES
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [230-529]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FWHEQSRPDR DQYVTVRWEN IDKDSKGQFL KEDPDDVDNA GVPYDYGSIM HYRSKAFSKF  60
   61 DDLYTISTYV TDYQKTIGQR DQLSFNDIRL MNKIYCSAVC PSKLPCQRGG YTDPRRCDRC 120
  121 RCPDGFTGQY CEQVMPGYGA TCGGKISLTR STTRISSPGY PREFKEGQEC SWLLVAPPGH 180
  181 IVEFQFIGEF EMYCKIRHSL CMDYVEVRNS TDFANTGMRY CCYGTPPTRI RSATTDMVVL 240
  241 FRSFYRGGKG FEARARAVPE WGASRNTNLQ YSSLYGYVRS ETGGRGSMWR FPFFVTRRPL 300
  301 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.045757
Match: 1nt0A
Description: Mannose-binding protein associated serine protease 2, MASP2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 2.03786631670095 bayes_pls_golite062009
receptor binding 1.94948331803509 bayes_pls_golite062009
receptor activity 1.17703206127603 bayes_pls_golite062009
hydrolase activity 1.12447587972667 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 1.10435298721188 bayes_pls_golite062009
endopeptidase activity 1.03668892056053 bayes_pls_golite062009
ErbB-3 class receptor binding 1.02450424977847 bayes_pls_golite062009
ErbB-2 class receptor binding 0.728290475143461 bayes_pls_golite062009
binding 0.708339313156457 bayes_pls_golite062009
metallopeptidase activity 0.623476257655953 bayes_pls_golite062009
epidermal growth factor receptor binding 0.58090527719405 bayes_pls_golite062009
metalloendopeptidase activity 0.508669171144608 bayes_pls_golite062009
protein binding 0.475826109910145 bayes_pls_golite062009
transcription factor binding 0.30492109086541 bayes_pls_golite062009
signal transducer activity 0.266830350139867 bayes_pls_golite062009
molecular transducer activity 0.266830350139867 bayes_pls_golite062009
growth factor activity 0.190406928940325 bayes_pls_golite062009
catalytic activity 0.075748351866431 bayes_pls_golite062009

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