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View Structure Prediction Details

Protein: gi|39545896, gi|...
Organism: Arabidopsis thaliana
Length: 261 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|39545896, gi|....

Description E-value Query
Range
Subject
Range
gi|220952660, gi... - gi|220952660|gb|ACL88873.1| TfIIFbeta-PA [synthetic construct], gi|220942436|gb|ACL83761.1| TfIIFbet...
TfIIFbeta-PA - The gene Transcription factor TFIIF√?Ž√?¬≤ is referred to in FlyBase by the symbol Dmel\TfIIF√?...
299.0 [0..4] [253..13]

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Predicted Domain #1
Region A:
Residues: [1-122]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEDIHNLDIE KSDRSIWLMK CPVVVDKAWH KIAASSSSSF ASSDSPPDMA KIVREVDPLR  60
   61 DDSPPEFKMY MVGAEYGNMP KCYALNMFTD FVPMGGFSDV NQGCAAAEGK VDHKFDMKPY 120
  121 GE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 26.30103
Match: 1f3uA
Description: TFIIF beta subunit, Rap30
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
general RNA polymerase II transcription factor activity 10.2797850053222 bayes_pls_golite062009
transcription initiation factor activity 6.22439849848084 bayes_pls_golite062009
RNA polymerase II transcription factor activity 4.06672086326535 bayes_pls_golite062009
transcription regulator activity 3.89911747857156 bayes_pls_golite062009
binding 2.6963272883422 bayes_pls_golite062009
transcription coactivator activity 1.30173573105398 bayes_pls_golite062009
protein binding 1.06175937412568 bayes_pls_golite062009
transcription activator activity 0.800371882273381 bayes_pls_golite062009
transcription factor binding 0.677361513203971 bayes_pls_golite062009
transcription cofactor activity 0.43974291826617 bayes_pls_golite062009
catalytic activity 0.304516551414824 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [123-261]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TIEEYARLCR ERTSKAMVKN RQIQVIDNDR GVHMRPMPGM LGLVSSNSKE KRKPPPVKQT  60
   61 EVKRTRRDRG ELEAIMFKLF EGQPNWTLKQ LVQETDQPAQ FLKEILNELC VYNKRGSNQG 120
  121 TYELKPEYKK SAEDDTGGQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.0
Match: 1bbyA
Description: DNA-BINDING DOMAIN FROM HUMAN RAP30, NMR, MINIMIZED AVERAGE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
general RNA polymerase II transcription factor activity 5.67074370996647 bayes_pls_golite062009
transcription regulator activity 5.55329976718261 bayes_pls_golite062009
DNA binding 4.84466441605416 bayes_pls_golite062009
nucleic acid binding 4.57954522145536 bayes_pls_golite062009
transcription factor activity 4.12685284895733 bayes_pls_golite062009
binding 4.05190810999633 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.60738445921725 bayes_pls_golite062009
sequence-specific DNA binding 2.3918869755162 bayes_pls_golite062009
transcription activator activity 2.37668609508629 bayes_pls_golite062009
transcription repressor activity 2.22485867684613 bayes_pls_golite062009
DNA-directed RNA polymerase activity 1.82365519759474 bayes_pls_golite062009
RNA polymerase activity 1.82365519759474 bayes_pls_golite062009
transcription elongation regulator activity 1.81270943531115 bayes_pls_golite062009
RNA binding 0.992043085614693 bayes_pls_golite062009
protein binding 0.961087148890615 bayes_pls_golite062009
transcription factor binding 0.85714789329232 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.66743181561551 bayes_pls_golite062009
nucleotidyltransferase activity 0.237727660028553 bayes_pls_golite062009
positive transcription elongation factor activity 0.13524243942225 bayes_pls_golite062009
structural molecule activity 0.111941063082739 bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding 0.0360186926687502 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle