YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: GCH1_ARATH
Organism: Arabidopsis thaliana
Length: 466 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GCH1_ARATH.

Description E-value Query
Range
Subject
Range
gi|19909132 - gi|19909132|gb|AAM03126.1|AF489530_1 GTP cyclohydrolase I [Arabidopsis thaliana]
512.0 [0..1] [466..1]

Back

Predicted Domain #1
Region A:
Residues: [1-235]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGALDEGCLN LELDIGMKNG CIELAFEHQP ETLAIQDAVK LLLQGLHEDV NREGIKKTPF  60
   61 RVAKALREGT RGYKQKVKDY VQSALFPEAG LDEGVGQAGG VGGLVVVRDL DHYSYCESCL 120
  121 LPFHVKCHIG YVPSGQRVLG LSKFSRVTDV FAKRLQDPQR LADDICSALQ HWVKPAGVAV 180
  181 VLECSHIHFP SLDLDSLNLS SHRGFVKLLV SSGSGVFEDE SSNLWGEFQS FLMFK

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 8.45
Match: 1wm9A
Description: Structure of GTP cyclohydrolase I from Thermus thermophilus HB8
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
GTP cyclohydrolase I activity 4.58215881457764 bayes_pls_golite062009
cyclohydrolase activity 3.1225900680321 bayes_pls_golite062009
GTP cyclohydrolase activity 2.816522292063 bayes_pls_golite062009
6-pyruvoyltetrahydropterin synthase activity 2.34489533040902 bayes_pls_golite062009
catalytic activity 2.02879677696451 bayes_pls_golite062009
dihydroneopterin aldolase activity 1.4000306436633 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 1.2538657804327 bayes_pls_golite062009
binding 1.23408359924301 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 0.627364990614658 bayes_pls_golite062009
protein binding 0.316566321438364 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [236-466]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GVKTQALCRN GSSVKEWCPS VKSSSKLSPE VDPEMVSAVV SILKSLGEDP LRKELIATPT  60
   61 RFLKWMLNFQ RTNLEMKLNS FNPAKVNGEV KEKRLHCELN MPFWSMCEHH LLPFYGVVHI 120
  121 GYFCAEGSNP NPVGSSLMKA IVHFYGFKLQ VQERMTRQIA ETLSPLVGGD VIVVAEAGHT 180
  181 CMISRGIEKF GSSTATIAVL GRFSSDNSAR AMFLDKIHTT NALKTESSSP F

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 80.39794
Match: 1is7A
Description: GTP cyclohydrolase I
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
GTP cyclohydrolase I activity 5.27071565931386 bayes_pls_golite062009
cyclohydrolase activity 3.66553359909123 bayes_pls_golite062009
GTP cyclohydrolase activity 3.44912994722205 bayes_pls_golite062009
6-pyruvoyltetrahydropterin synthase activity 2.94513271787536 bayes_pls_golite062009
catalytic activity 2.20788162511962 bayes_pls_golite062009
dihydroneopterin aldolase activity 1.96466418682643 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 1.73101699306211 bayes_pls_golite062009
binding 1.19587307204017 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 0.974891318710762 bayes_pls_golite062009
protein binding 0.298277659609786 bayes_pls_golite062009
urate oxidase activity 0.0294957696532921 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle