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View Structure Prediction Details

Protein: gi|25302173, gi|...
Organism: Arabidopsis thaliana
Length: 618 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|25302173, gi|....

Description E-value Query
Range
Subject
Range
gi|77975004, gi|... - gi|77975004|ref|ZP_00830541.1| COG0475: Kef-type K+ transport systems, membrane components [Yersinia...
332.0 [0..12] [609..4]

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Predicted Domain #1
Region A:
Residues: [1-189]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIPHQEVNEE EASLFDFLWL LLASVIFVPL FQKIPGGSPV LGYLAAGILI GPYGLSIIRN  60
   61 VHGTRAIAEF GVVFLLFNIG LELSVERLSS MKKYVFGLGS AQVLVTAAVV GLLAHYVAGQ 120
  121 AGPAAIVIGN GLALSSTAVV LQVLQERGES TSRHGRASFS VLLFQDLAVV VLLILIPLIS 180
  181 PNSSKGGIG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [190-296]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FQAIAEALGL AAVKAAVAIT AIIAGGRLLL RPIYKQIAEN RNAEIFSANT LLVILGTSLL  60
   61 TARAGLSMAL GAFLAGLLLA ETEFSLQVES DIAPYRGLLL GLFFMTV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [297-618]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GMSIDPKLLL SNFPVIVGTL GLLIVGKTML VVIMGKLFGI SIISAIRVGL LLAPGGEFAF  60
   61 VAFGEAVNQG IMSPQLSSLL FLVVGISMAI TPWLAAGGQL IASRFELHDV RSLLPVESET 120
  121 DDLQGHIIIC GFGRVGQIIA QLLSERLIPF VALDVSSDRV TIGRSLDLPV YFGDAGSKEV 180
  181 LHKIGAGRAC AAVVALDAPG ANYRCVWALS KFYPNVKTFV RAHDVVHGLN LEKAGATAVV 240
  241 PETLEPSLQL AAAVLAQAKL PTSEIANTIN EFRTRHLSEL TELCEASGSS LGYGYSRTSK 300
  301 PKPQPSDASG DNQIIEGGTV VI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.0
Match: 1lnqA
Description: Potassium channel-related protein MthK
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
potassium channel activity 7.45561375804942 bayes_pls_golite062009
voltage-gated potassium channel activity 7.44058571110681 bayes_pls_golite062009
voltage-gated cation channel activity 7.3386698127529 bayes_pls_golite062009
voltage-gated ion channel activity 7.16469552587678 bayes_pls_golite062009
voltage-gated channel activity 7.14063840809955 bayes_pls_golite062009
metal ion transmembrane transporter activity 5.93188092092616 bayes_pls_golite062009
cation channel activity 5.49362429102263 bayes_pls_golite062009
cation transmembrane transporter activity 5.13805155650973 bayes_pls_golite062009
inward rectifier potassium channel activity 5.0997110076666 bayes_pls_golite062009
ion transmembrane transporter activity 5.04374327766634 bayes_pls_golite062009
ion channel activity 4.88752793243149 bayes_pls_golite062009
gated channel activity 4.87650815860853 bayes_pls_golite062009
substrate-specific channel activity 4.76774891791883 bayes_pls_golite062009
channel activity 4.7460548761362 bayes_pls_golite062009
passive transmembrane transporter activity 4.7460548761362 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 4.64120459994573 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 3.48222081117811 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 2.96809690970616 bayes_pls_golite062009
ligand-gated ion channel activity 2.94075163359893 bayes_pls_golite062009
ligand-gated channel activity 2.94075163359893 bayes_pls_golite062009
transporter activity 2.93091397928047 bayes_pls_golite062009
transmembrane transporter activity 2.82224868778929 bayes_pls_golite062009
substrate-specific transporter activity 2.79688978937497 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 2.13014428099026 bayes_pls_golite062009
potassium ion transmembrane transporter activity 1.34449386905866 bayes_pls_golite062009
catalytic activity 1.03099072397093 bayes_pls_golite062009
active transmembrane transporter activity 0.239024094835991 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle