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View Structure Prediction Details

Protein: UCH2_ARATH
Organism: Arabidopsis thaliana
Length: 330 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UCH2_ARATH.

Description E-value Query
Range
Subject
Range
gi|15724238 - gi|15724238|gb|AAL06512.1|AF412059_1 F5I14.29/F5I14.29 [Arabidopsis thaliana]
416.0 [0..1] [330..1]

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Predicted Domain #1
Region A:
Residues: [1-222]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSWCTIESDP GVFTELIQQM QVKGVQVEEL YSLDSDSLNN LRPVYGLIFL FKWQAGEKDE  60
   61 RPTIQDQVSN LFFANQVINN ACATQAILAI LLNSPEVDIG PELSALKEFT KNFPSDLKGL 120
  121 AINNSDSIRA AHNSFARPEP FVPEEQKAAT KDDDVYHFIS YIPVDGVLYE LDGLKEGPIS 180
  181 LGPCPGDQTG IEWLQMVQPV IQERIERYSQ SEIRFNLLAV IK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 69.522879
Match: 1uchA
Description: DEUBIQUITINATING ENZYME UCH-L3 (HUMAN) AT 1.8 ANGSTROM RESOLUTION
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 7.38847948226412 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 7.21002260103248 bayes_pls_golite062009
endopeptidase activity 6.57191549077589 bayes_pls_golite062009
cysteine-type peptidase activity 6.54685807643041 bayes_pls_golite062009
small conjugating protein-specific protease activity 6.39247995905454 bayes_pls_golite062009
ubiquitin-specific protease activity 5.91394445088241 bayes_pls_golite062009
hydrolase activity 4.82615927403291 bayes_pls_golite062009
ubiquitin thiolesterase activity 4.1832081096766 bayes_pls_golite062009
thiolester hydrolase activity 2.96735553959103 bayes_pls_golite062009
SUMO-specific protease activity 2.65263825059319 bayes_pls_golite062009
cysteine-type endopeptidase activity 1.95802900199539 bayes_pls_golite062009
binding 1.3276268995308 bayes_pls_golite062009
catalytic activity 1.05972260874031 bayes_pls_golite062009
protein binding 0.896934807256194 bayes_pls_golite062009
NEDD8-specific protease activity 0.687958315289315 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 0.495951820083869 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.467924587720185 bayes_pls_golite062009
nucleic acid binding 0.439226369799415 bayes_pls_golite062009
calcium-dependent cysteine-type endopeptidase activity 0.196538841514154 bayes_pls_golite062009
DNA binding 0.168761518285256 bayes_pls_golite062009
transferase activity 0.0852393573521809 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [223-330]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NRKDIYTAEL KELQRQREQL LQQANTCVDK SEAEAVNALI AEVGSGIEAA SDKIVMEEEK  60
   61 FMKWRTENIR RKHNYIPFLF NFLKLLAEKK QLKPLIEKAK KQKTESST

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle