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View Structure Prediction Details

Protein: ADHL2_ARATH
Organism: Arabidopsis thaliana
Length: 386 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ADHL2_ARATH.

Description E-value Query
Range
Subject
Range
gi|116127972, gi... - gi|118785202|ref|XP_314472.3| ENSANGP00000020590 [Anopheles gambiae str. PEST], gi|116127972|gb|EAA0...
AGAP010499-PA - AD20590: |protein_coding|3L:5054374:5055589:1|gene:AGAP010499
397.0 [0..4] [384..1]

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Predicted Domain #1
Region A:
Residues: [1-386]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDKASITEGK PIRCKAAILR KAGEPLVIEE IQVDPPQAYE VRIKILCTSL CHTDVTFWKL  60
   61 DSGPLARFPR ILGHEAVGVV ESIGEKVDGF KQGDVVLPVF HPQCEECKEC ISPKSNWCTK 120
  121 YTNDYLSNTR RYGMTSRFKD SRGEDIHHFI FVSSFTEYTV VDIAHLVKIS PEIPVDIAAL 180
  181 LSCSVATGLG AAWKVADVEE GSTVVIFGLG AVGLAVAEGV RLRGAAKIIG VDLNPAKFEI 240
  241 GKRFGITDFV NPALCGEKTI SEVIREMTDV GADYSFECIG LASLMEEAFK STRPGSGKTI 300
  301 VLGMEQKALP ISLGSYDLLR GRTVCGTLFG GLKPKLDIPI LVDRYLKKEL NLEDLITHEL 360
  361 SFEEINKAFH LLAEGNSIRC IIWMDK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 104.0
Match: 1hdyA
Description: Alcohol dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ethanol binding 4.47659026306883 bayes_pls_golite062009
NAD or NADH binding 4.35058438816264 bayes_pls_golite062009
retinol dehydrogenase activity 4.1750549780559 bayes_pls_golite062009
oxidoreductase activity 3.09625241707629 bayes_pls_golite062009
L-iditol 2-dehydrogenase activity 3.00103406168296 bayes_pls_golite062009
alcohol binding 2.97042200128883 bayes_pls_golite062009
alcohol dehydrogenase (NAD) activity 2.94416173750168 bayes_pls_golite062009
retinol binding 2.89007863838685 bayes_pls_golite062009
all-trans retinal binding 2.84803957533249 bayes_pls_golite062009
S-(hydroxymethyl)glutathione dehydrogenase activity 2.58673703881996 bayes_pls_golite062009
hydroxymethylfurfural reductase (NADH) activity 2.2999175117758 bayes_pls_golite062009
hydroxymethylfurfural reductase activity 2.2999175117758 bayes_pls_golite062009
alcohol dehydrogenase activity, zinc-dependent 2.26153457113968 bayes_pls_golite062009
NADPH:quinone reductase activity 2.16668841986245 bayes_pls_golite062009
benzaldehyde dehydrogenase activity 2.03039843216597 bayes_pls_golite062009
catalytic activity 1.79741889688267 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 1.65338499044318 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1.47309297191111 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor 1.29842732066898 bayes_pls_golite062009
chaperone binding 1.19079350615542 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH 1.01627645289834 bayes_pls_golite062009
binding 0.784517759335365 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors 0.62461633437589 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 0.527946013169731 bayes_pls_golite062009
DNA binding 0.525227236870065 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.484089941059577 bayes_pls_golite062009
kinase activity 0.461063813999598 bayes_pls_golite062009
nucleic acid binding 0.459537641913493 bayes_pls_golite062009
hydroxymethylfurfural reductase (NADPH) activity 0.382131941157781 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.375415252607746 bayes_pls_golite062009
coenzyme binding 0.35922330382799 bayes_pls_golite062009
protein kinase activity 0.339420053437627 bayes_pls_golite062009
3-hydroxyacyl-CoA dehydrogenase activity 0.233238483713519 bayes_pls_golite062009
methylenetetrahydrofolate dehydrogenase activity 0.169301675015808 bayes_pls_golite062009
methenyltetrahydrofolate cyclohydrolase activity 0.162625185692811 bayes_pls_golite062009
transcription regulator activity 0.152651308844322 bayes_pls_golite062009
fatty acid synthase activity 0.0962368786590111 bayes_pls_golite062009

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Created and Maintained by: Michael Riffle