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View Structure Prediction Details

Protein: ACCR4_ARATH
Organism: Arabidopsis thaliana
Length: 751 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ACCR4_ARATH.

Description E-value Query
Range
Subject
Range
gi|116311954 - gi|116311954|emb|CAJ86314.1| H0525G02.11 [Oryza sativa (indica cultivar-group)]
396.0 [0..1] [747..155]

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Predicted Domain #1
Region A:
Residues: [1-281]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALTISISCF SSYFVSLLLL VLSSFSFVCF SLSTVSISHI SNQTLVCALN NHSYLQCSSF  60
   61 PLNSIPFSLT GNLRNRRFSG VVSGNGFVCG LISRLDSNTS TLLCWRFSVD GTNMLHKRIY 120
  121 HGPELEELEA GNFRICGVER VSRRLRCWQP YYLPRPDNYR SIALGDNFFC GLSQPPGMIS 180
  181 CEGIAKVPSG DHYIAIAAGS RQACAITVDN DVECWGQTQS LPREKFLALA VGEDRGCGVR 240
  241 WSNGTVVCWG NNNNFSLPQT LKDIHFTSIY AKGPMFCGVA T

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.39794
Match: 1ookG
Description: von Willebrand factor binding domain of glycoprotein Ib alpha
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
signal transducer activity 2.54176035045352 bayes_pls_golite062009
molecular transducer activity 2.54176035045352 bayes_pls_golite062009
receptor activity 2.44108148686445 bayes_pls_golite062009
transmembrane receptor activity 2.25077658159974 bayes_pls_golite062009
binding 1.87302803330255 bayes_pls_golite062009
protein kinase activity 1.43632437878638 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.16530645523007 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.12585418084562 bayes_pls_golite062009
kinase activity 1.11577341189523 bayes_pls_golite062009
G-protein coupled receptor activity 1.04507575991279 bayes_pls_golite062009
protein binding 0.646159692466759 bayes_pls_golite062009
transferase activity 0.435331931559158 bayes_pls_golite062009
nucleic acid binding 0.370391722473665 bayes_pls_golite062009
protein tyrosine kinase activity 0.231213253402712 bayes_pls_golite062009
enzyme regulator activity 0.154501444195573 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [282-343]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RNYTLICWGN ENFKSGVFTP FQGLISQVVM PGPCRRECPY RPLSGSQSLC GNELMICDLK  60
   61 RN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [344-751]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DGEFPDTRAQ NSKNKTWSRR NIAFLVVGCV GTFSLLLVIS FLIFKSHCRC RVHDSGRLDD  60
   61 TRTIDIPKLE KRLCTLASLG NPGQLMEFSI DELALATDGF SVRFHLGIGS FGSVYQGVLS 120
  121 DGRHVAIKRA ELTNPTLSGT TMRHRRADKD SAFVNELESM SRLNHKNLVR LLGFYEDTEE 180
  181 RILVYEYMKN GSLADHLHNP QFDPLSWQTR LMIALDAARG IQYLHEFIVP PVIHRDIKSS 240
  241 NILLDATWTA KVSDFGLSQM GPTEEDDVSH LSLHAAGTLG YIDPEYYKFQ QLTTKSDVYS 300
  301 FGVVLLELLS GHKAIHNNED ENPRNLVEYV VPYILLDEAH RILDQRIPPP TPYEIEAVAH 360
  361 VGYLAAECLM PCSRKRPSMV EVVSKLESAL AACLTAPKTE TVSRSNTY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 64.221849
Match: 1fmkA
Description: CRYSTAL STRUCTURE OF HUMAN TYROSINE-PROTEIN KINASE C-SRC
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein kinase activity 5.4586557943719 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 5.04467222534257 bayes_pls_golite062009
kinase activity 4.85903980916957 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 4.63692708178478 bayes_pls_golite062009
protein serine/threonine kinase activity 4.46381887831481 bayes_pls_golite062009
transferase activity 3.26787750561728 bayes_pls_golite062009
protein tyrosine kinase activity 2.8153155526437 bayes_pls_golite062009
binding 2.74863538127007 bayes_pls_golite062009
molecular transducer activity 2.40586892801446 bayes_pls_golite062009
signal transducer activity 2.40586892801446 bayes_pls_golite062009
receptor signaling protein activity 2.10379226653669 bayes_pls_golite062009
ATP binding 1.97600611746091 bayes_pls_golite062009
adenyl ribonucleotide binding 1.93596671856664 bayes_pls_golite062009
adenyl nucleotide binding 1.90928021591891 bayes_pls_golite062009
receptor signaling protein serine/threonine kinase activity 1.81249386965144 bayes_pls_golite062009
molecular adaptor activity 1.81145713371725 bayes_pls_golite062009
transmembrane receptor protein kinase activity 1.7769021678395 bayes_pls_golite062009
transmembrane receptor activity 1.6878868450299 bayes_pls_golite062009
purine ribonucleotide binding 1.65732943334212 bayes_pls_golite062009
ribonucleotide binding 1.65726906484847 bayes_pls_golite062009
purine nucleotide binding 1.63763394711025 bayes_pls_golite062009
nucleotide binding 1.63195828048121 bayes_pls_golite062009
SH3/SH2 adaptor activity 1.59474164216385 bayes_pls_golite062009
receptor activity 1.57112777506542 bayes_pls_golite062009
transmembrane receptor protein tyrosine kinase activity 1.4571078357189 bayes_pls_golite062009
protein binding 1.22565748038754 bayes_pls_golite062009
catalytic activity 1.21655087018101 bayes_pls_golite062009
transporter activity 1.07717671444596 bayes_pls_golite062009
transmembrane transporter activity 0.93867354225509 bayes_pls_golite062009
protein binding, bridging 0.83823250804321 bayes_pls_golite062009
MAP kinase activity 0.81943579965027 bayes_pls_golite062009
MAP kinase kinase activity 0.610230065465794 bayes_pls_golite062009
cyclin-dependent protein kinase activity 0.499492353295369 bayes_pls_golite062009
substrate-specific transporter activity 0.419967454336647 bayes_pls_golite062009
magnesium ion binding 0.393328812780268 bayes_pls_golite062009
insulin receptor activity 0.35140991120688 bayes_pls_golite062009
insulin binding 0.326213234151689 bayes_pls_golite062009
phosphoinositide 3-kinase binding 0.30293890086301 bayes_pls_golite062009
kinase binding 0.26752427107238 bayes_pls_golite062009
transmembrane receptor protein serine/threonine kinase activity 0.26602283402868 bayes_pls_golite062009
transforming growth factor beta receptor activity 0.26602283402868 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.176810368721201 bayes_pls_golite062009
growth factor binding 0.0526340287295695 bayes_pls_golite062009
PTB domain binding 0.0449060071013108 bayes_pls_golite062009
protein kinase binding 0.00674998152095019 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle