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View Structure Prediction Details

Protein: nas-27
Organism: Caenorhabditis elegans
Length: 428 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nas-27.

Description E-value Query
Range
Subject
Range
gi|115730804, gi... - gi|115946638|ref|XP_001193347.1| PREDICTED: similar to blastula protease-10 [Strongylocentrotus purp...
274.0 [0..5] [426..16]

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Predicted Domain #1
Region A:
Residues: [1-178]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQILPIFFPL LITSLHAIPR GRRAVRNRNE GDINSLVGVG QYLYQGDIAV VKSRARRAVI  60
   61 RQKHKKWKLP MPYSFDRNFP SRSRQRVLEA MQFWSEKTCV TFHENRYVYP HVSIFEGNGC 120
  121 WSFVGKQPSL REQSLSLERS CTDHTFVVAH EIAHTLGFYH EHARGDRDQF ISIDYSNV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 34.39794
Match: 1astA
Description: STRUCTURE OF ASTACIN AND IMPLICATIONS FOR ACTIVATION OF ASTACINS AND ZINC-LIGATION OF COLLAGENASES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 3.87713655504947 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 3.50720289959102 bayes_pls_golite062009
metallopeptidase activity 2.55317823694462 bayes_pls_golite062009
endopeptidase activity 2.52973705827479 bayes_pls_golite062009
hydrolase activity 2.30803642767787 bayes_pls_golite062009
metalloendopeptidase activity 1.81132179546381 bayes_pls_golite062009
catalytic activity 1.26162753036584 bayes_pls_golite062009
exopeptidase activity 0.71491631246151 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [179-428]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NPNLTFAFAK ESEKQLDHQE AAYEYGSVMH YSVDQFAVNT NRPVIYARDQ KFAQAMGNRM  60
   61 RATFQDVSRM NVLYNCHERC ANTLNRCQQG GYPAPSDCSQ CVCPDGFGGN FCETIEAHSV 120
  121 GQKDNSDCGG VLWASETSQT FYGAVRTRVH SNSVLPTPEH CFWHIRASQG KSIEIQIKNI 180
  181 ISPCSMSCSF NALELKLSNF TMTGPRFCCD EHIYNRYSQP KVFQSEGPLA VIGAYARYDY 240
  241 LDFNIEYRAV 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.0
Match: 1nt0A
Description: Mannose-binding protein associated serine protease 2, MASP2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 1.72322649047672 bayes_pls_golite062009
binding 0.945822943902565 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 0.759649002808058 bayes_pls_golite062009
hydrolase activity 0.647380592098528 bayes_pls_golite062009
endopeptidase activity 0.58509255952441 bayes_pls_golite062009
protein binding 0.513051538906644 bayes_pls_golite062009
catalytic activity 0.34605294925773 bayes_pls_golite062009
receptor binding 0.0218857243240818 bayes_pls_golite062009

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