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View Structure Prediction Details

Protein: nas-12
Organism: Caenorhabditis elegans
Length: 384 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nas-12.

Description E-value Query
Range
Subject
Range
gi|187036614, gi... - gi|39585704|emb|CAE59906.1| Hypothetical protein CBG03390 [Caenorhabditis briggsae], gi|187036614|em...
gi|157756895 - gi|157756895|ref|XP_001670791.1| Hypothetical protein CBG03390 [Caenorhabditis briggsae AF16]
281.0 [0..1] [384..1]

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Predicted Domain #1
Region A:
Residues: [1-268]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLYIPQFSIY FCLGYLLLFC KISNAVKQSW EINQELITEA NKEHTVFGDM LLTPAQLIRY  60
   61 ENSKDSDLSI RGVSIKGSSM NRWSNNIVPY VISPQYSPAQ KQILVSSLRY FERVSCFKFV 120
  121 ERTTQNDYLF IVPLDGCYSY VGKIGGRQTL SLAADCIADY IIWHEMMHAI GFEHEHQRPD 180
  181 RDSFIRVDYA NVIPGQMINF DKLKTSHVEY PDIYDFKSIM HYDGYAFGRV DTARRVRLAT 240
  241 MTPLKPGVTL EDNMKFTATD IEKLNRLG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 44.69897
Match: 1astA
Description: STRUCTURE OF ASTACIN AND IMPLICATIONS FOR ACTIVATION OF ASTACINS AND ZINC-LIGATION OF COLLAGENASES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 3.87713655504947 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 3.50720289959102 bayes_pls_golite062009
metallopeptidase activity 2.55317823694462 bayes_pls_golite062009
endopeptidase activity 2.52973705827479 bayes_pls_golite062009
hydrolase activity 2.30803642767787 bayes_pls_golite062009
metalloendopeptidase activity 1.81132179546381 bayes_pls_golite062009
catalytic activity 1.26162753036584 bayes_pls_golite062009
exopeptidase activity 0.71491631246151 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [269-384]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QCGARGGQYS NQGVVASTCQ DVATAVSCEG NRRRGMCKNP FYKQMMIKSC QKTCRLCSYT  60
   61 RMIDEDDDLT PNTTVKSVKC EDKHPRCDIY SHNGFCTLPF YDDVRYQLCA KTCNLC

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.962
Match: 1zlgA
Description: No description for 1zlgA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle