| Protein: | aph-2 |
| Organism: | Caenorhabditis elegans |
| Length: | 723 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for aph-2.
| Description | E-value | Query Range |
Subject Range |
|
|
746.0 | [0..3] | [717..19] |
|
Region A: Residues: [1-134] |
1 11 21 31 41 51
| | | | | |
1 MKKWLVIVLI IAGIRCDGFS DQVFRTLFIG EGNACYRTFN KTHEFGCQAN RENENGLIVR 60
61 IDKQEDFKNL DSCWNSFYPK YSGKYWALLP VNLIRRDTIS QLKSSKCLSG IVLYNSGESI 120
121 HPGDESTAAS HDAE
|
| Detection Method: |  |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [135-558] |
1 11 21 31 41 51
| | | | | |
1 CPNAASDYYL QDKNEEYCER KINSRGAITR DGLMKIDWRI QMVFIDNSTD LEIIEKCYSM 60
61 FNKPKEDGSS GYPYCGMSFR LANMAAGNSE ICYRRGKNDA KLFQMNIDSG DAPQLCGAMH 120
121 SDNIFAFPTP IPTSPTNETI ITSKYMMVTA RMDSFGMIPE ISVGEVSVLT SIISVLAAAR 180
181 SMGTQIEKWQ KASNTSNRNV FFAFFNGESL DYIGSGAAAY QMENGKFPQM IRSDRTHIHP 240
241 IRPNELDYIL EVQQIGVAKG RKYYVHVDGE RYQQNKTQTD RVIDRIERGL RSHAFDLEKP 300
301 SGSGDRVPPA SWHSFAKADA HVQSVLLAPY GKEYEYQRVN SILDKNEWTE DEREKAIQEI 360
361 EAVSTAILAA AADYVGVETD EVVAKVDKKL ITTIFDCLIT SNFWFDCDFM QKLDGGRYHK 420
421 LFNS
|
| Detection Method: | |
| Confidence: | 31.09691 |
| Match: | 1de4C |
| Description: | Transferrin receptor ectodomain, C-terminal domain; Transferrin receptor ectodomain, apical domain; Transferrin receptor ectodomain, protease-like domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| peptidase activity | 3.76097450390625 | bayes_pls_golite062009 |
| transmembrane receptor activity | 3.68442839136734 | bayes_pls_golite062009 |
| receptor activity | 3.43249110530054 | bayes_pls_golite062009 |
| hydrolase activity | 2.71452093699272 | bayes_pls_golite062009 |
| signal transducer activity | 2.61784313760368 | bayes_pls_golite062009 |
| molecular transducer activity | 2.61784313760368 | bayes_pls_golite062009 |
| peptidase activity, acting on L-amino acid peptides | 2.16368706007937 | bayes_pls_golite062009 |
| catalytic activity | 0.463274780485604 | bayes_pls_golite062009 |
| metallopeptidase activity | 0.0887519845185331 | bayes_pls_golite062009 |
|
Region A: Residues: [559-723] |
1 11 21 31 41 51
| | | | | |
1 YGFNQKSTYI SMESHTAFPT VLHWLTIFAL GSDKETLNVK SEKSCSHLGQ FQAFQMYTYT 60
61 WQPNPYTGNF SCLKSAIVKK VMVSPAVDSQ TPEEEMNTRY STWMESVYII ESVNLYLMED 120
121 ASFEYTMILI AVISALLSIF AVGRCSETTF IVDEGEPAAE GGEPL
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
