| Protein: | lev-8 |
| Organism: | Caenorhabditis elegans |
| Length: | 531 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for lev-8.
| Description | E-value | Query Range |
Subject Range |
|
|
426.0 | [0..6] | [529..2] |
|
Region A: Residues: [1-355] |
1 11 21 31 41 51
| | | | | |
1 MWIPQRISHI FLLVIFILHI VTINANKHVS QLLENLLTDY NKAVRPVHNA SDALKVKFGA 60
61 NLCRLIDVDE VNQVLTTSLW LEMQWYDKKL TWNPTDWGGV EYIHIPSDQI WIPDIVLYNN 120
121 ADGEPHITIT SLAKIDHHGR VVWQPPSIYK SFCPINIKYF PYDWQTCEMK FGGWSNDGET 180
181 LDLYQIPVDV DDIPQVKRQD DGVEFLYLEK GLGLSFYHES AEWDLLSATS SRYAQIYPGC 240
241 CGQQYYIDIK YRIIIRRKAI FFTVTLTIPC MLIANVTPFV FLILPNEHKM TYSISVLVAF 300
301 SVFYLVLIDL IPPTSLSLSL IGIYLLFTLL MVSVSIILSV VTINMYRKQA FSSGM
|
| Detection Method: |  |
| Confidence: | 79.0 |
| Match: | 2bg9A |
| Description: | Refined structure of the nicotinic acetylcholine receptor at 4A resolution. |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [356-531] |
1 11 21 31 41 51
| | | | | |
1 SHWQRWLFVQ RLPKLLRLKT LEHTLGPDEG SETTTPRTGS VSVTASVTQR TLNPNNNSPV 60
61 FPPQRLRLLS LVQMDEALKQ RCAADNLDLF RKIAGHLKII SAHFHNQQME GKITEEWQLM 120
121 SLVIDRIFLI LFLAVSMAAN IMFVYNSPTL FDDRPSLVPS VAHKPLSGGT INVLNT
|
| Detection Method: | |
| Confidence: | 42.154902 |
| Match: | 1oedB |
| Description: | Acetylcholine receptor protein, beta chain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| acetylcholine binding | 13.9752632471881 | bayes_pls_golite062009 |
| acetylcholine receptor activity | 13.7533645836795 | bayes_pls_golite062009 |
| nicotinic acetylcholine-activated cation-selective channel activity | 13.1511875247796 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 11.9525876011069 | bayes_pls_golite062009 |
| extracellular ligand-gated ion channel activity | 11.7813202122163 | bayes_pls_golite062009 |
| excitatory extracellular ligand-gated ion channel activity | 11.7813202122163 | bayes_pls_golite062009 |
| cation channel activity | 11.7442066737514 | bayes_pls_golite062009 |
| ion channel activity | 11.1753684044644 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 11.0903806681397 | bayes_pls_golite062009 |
| channel activity | 11.0903806681397 | bayes_pls_golite062009 |
| gated channel activity | 11.0397691626728 | bayes_pls_golite062009 |
| substrate-specific channel activity | 10.9375522860542 | bayes_pls_golite062009 |
| ligand-gated ion channel activity | 9.34902726749692 | bayes_pls_golite062009 |
| ligand-gated channel activity | 9.34902726749692 | bayes_pls_golite062009 |
| amine binding | 9.11982124959723 | bayes_pls_golite062009 |
| chloride channel regulator activity | 9.10587892909341 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 7.22265353460749 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 7.19173677417054 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 6.7875346065164 | bayes_pls_golite062009 |
| transmembrane receptor activity | 5.4080353535498 | bayes_pls_golite062009 |
| receptor activity | 5.11329651194787 | bayes_pls_golite062009 |
| transporter activity | 5.11262082564788 | bayes_pls_golite062009 |
| transmembrane transporter activity | 5.03439798256257 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 4.91314874981447 | bayes_pls_golite062009 |
| neurotransmitter binding | 4.25797760547212 | bayes_pls_golite062009 |
| neurotransmitter receptor activity | 4.15404686068319 | bayes_pls_golite062009 |
| signal transducer activity | 4.12549692767753 | bayes_pls_golite062009 |
| molecular transducer activity | 4.12549692767753 | bayes_pls_golite062009 |
| adenylate cyclase binding | 3.30190657223613 | bayes_pls_golite062009 |
| binding | 2.4916526322278 | bayes_pls_golite062009 |
| beta-amyloid binding | 2.25766805801029 | bayes_pls_golite062009 |
| GABA-A receptor activity | 2.17863682705001 | bayes_pls_golite062009 |
| 1.68370717591127 | bayes_pls_golite062009 | |
| channel regulator activity | 1.66978990310631 | bayes_pls_golite062009 |
| protein binding | 1.45740893920165 | bayes_pls_golite062009 |
| G-protein coupled receptor activity | 1.42422063123689 | bayes_pls_golite062009 |
| serotonin binding | 1.33584589886834 | bayes_pls_golite062009 |
| serotonin-activated cation-selective channel activity | 1.31324203158511 | bayes_pls_golite062009 |
| toxin binding | 1.03329843925063 | bayes_pls_golite062009 |
| drug binding | 0.64715018605883 | bayes_pls_golite062009 |
| kinase binding | 0.365355763029699 | bayes_pls_golite062009 |
| protein kinase binding | 0.350601457777817 | bayes_pls_golite062009 |
