| Protein: | pde-4 |
| Organism: | Caenorhabditis elegans |
| Length: | 674 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
|
Region A: Residues: [1-201] |
1 11 21 31 41 51
| | | | | |
1 MPRRRGSSSS SSAAGGSGGG GGFGFSSLRR ELHLHNFFRT SSPSASSTSR TPPAALPPRT 60
61 SAVTIPGSNH KLTSSASSYH PPRELTVSTF SAGSATAADG LGGAHLTPSL SSSVHARRES 120
121 FLYRASDDLR EASSLRPVSR ASSIASNEHG HGDDLIVTPF AQLLASLRNV RSNLISITNI 180
181 QNSDDSRHAN RSAKRPPLHN I
|
| Detection Method: |  |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [202-296] |
1 11 21 31 41 51
| | | | | |
1 ELPDDVVHCA HDTLEELDWC LDQLETIQTH RSVSEMASSK FRKMLNKELS HFAESSKSGT 60
61 QVSKFLITTY MDKEEDEPSI EIEVPTEVQG PSTSG
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [297-674] |
1 11 21 31 41 51
| | | | | |
1 PMTLSILKKA QTAAMNKISG VRKLRAPSHD GHVPEYGVNC AREIAVHMQR LDDWGPDVFK 60
61 IDELSKNHSL TVVTFSLLRQ RNLFKTFEIH QSTLVTYLLN LEHHYRNNHY HNFIHAADVA 120
121 QSMHVLLMSP VLTEVFTDLE VLAAIFAGAV HDVDHPGFTN QYLINSNNEL AIMYNDESVL 180
181 EQHHLAVAFK LLQDSNCDFL ANLSRKQRLQ FRKIVIDMVL ATDMSKHMSL LADLKTMVEA 240
241 KKVAGNNVIV LDKYNDKIQV LQSMIHLADL SNPTKPIELY QQWNQRIMEE YWRQGDKEKE 300
301 LGLEISPMCD RGNVTIEKSQ VGFIDYIVHP LYETWADLVY PDAQNILDQL EENREWYQSR 360
361 IPEEPDTART VTEDDEHK
|
| Detection Method: | |
| Confidence: | 127.0 |
| Match: | 1oynA |
| Description: | Catalytic domain of cyclic nucleotide phosphodiesterase pde4d |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| cyclic-nucleotide phosphodiesterase activity | 3.86434485322172 | bayes_pls_golite062009 |
| 3',5'-cyclic-nucleotide phosphodiesterase activity | 3.8566356686502 | bayes_pls_golite062009 |
| phosphoric diester hydrolase activity | 3.16734214417311 | bayes_pls_golite062009 |
| 3',5'-cyclic-AMP phosphodiesterase activity | 2.29938697204184 | bayes_pls_golite062009 |
| 3',5'-cyclic-GMP phosphodiesterase activity | 2.29281173183086 | bayes_pls_golite062009 |
| catalytic activity | 1.44092158711463 | bayes_pls_golite062009 |
| hydrolase activity | 1.06080266556153 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 0.815214868148798 | bayes_pls_golite062009 |
| phosphoric ester hydrolase activity | 0.196287846714023 | bayes_pls_golite062009 |
| binding | 0.0840884387362641 | bayes_pls_golite062009 |
