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View Structure Prediction Details

Protein: CE33003
Organism: Caenorhabditis elegans
Length: 724 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE33003.

Description E-value Query
Range
Subject
Range
gi|220956892, gi... - gi|220956892|gb|ACL90989.1| Nedd4-PD [synthetic construct], gi|220947460|gb|ACL86273.1| Nedd4-PD [sy...
Nedd4-PK - The gene Nedd4 is referred to in FlyBase by the symbol Dmel\Nedd4 (CG42279, FBgn0259174). It is a pr...
537.0 [0..17] [724..68]

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Predicted Domain #1
Region A:
Residues: [1-273]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVVQTVVHGY PPNTDNETEL LRVRLLRGTK LGKRDLLGVC SPYCMIRLEN SNGDTVDEVQ  60
   61 VETKKKTRNP TWNSVFTFRV TRACQMKILV YDENRLRKDV LMGFVSRTLN DGLITTQAPN 120
  121 PEEYALQSGT ASKGKSIGSL FLSFHFMPSS SDNSPSDSTA DLQQTSSGMP QGWEEREDGN 180
  181 GRTVYVNHAL RTTQFTPPES VSNGNVDAIT EQSVIEETRR RRDNYEHRSQ VTDEPSDTTI 240
  241 VSNELTAIDD AMRANFERGG GHVEEEEDEL RLP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.30103
Match: 1dqvA
Description: Synaptogamin I
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [274-344]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DGWDMQVAPN GRTFFIDHRT KTTTWTDPRP GAATRVPLLR GKTDDEIGAL PAGWEQRVHA  60
   61 DGRVFFIDHN R

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.01
Match: 1o6wA
Description: Splicing factor prp40
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ubiquitin-protein ligase activity 7.10194828712949 bayes_pls_golite062009
small conjugating protein ligase activity 6.82547847405261 bayes_pls_golite062009
acid-amino acid ligase activity 6.04482261304601 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 5.16615441408338 bayes_pls_golite062009
transcription regulator activity 3.182048695645 bayes_pls_golite062009
binding 2.56070278040924 bayes_pls_golite062009
protein binding 2.42069774848849 bayes_pls_golite062009
transcription activator activity 2.05338377709657 bayes_pls_golite062009
transcription factor binding 1.94857953695695 bayes_pls_golite062009
ligase activity 1.92115554795958 bayes_pls_golite062009
transcription cofactor activity 1.79381302696181 bayes_pls_golite062009
transcription repressor activity 1.7678419433602 bayes_pls_golite062009
transcription coactivator activity 1.67777735708173 bayes_pls_golite062009
histone methyltransferase activity 1.67021314973391 bayes_pls_golite062009
protein methyltransferase activity 0.9455445085372 bayes_pls_golite062009
protein-lysine N-methyltransferase activity 0.863094487787088 bayes_pls_golite062009
lysine N-methyltransferase activity 0.863094487787088 bayes_pls_golite062009
histone-lysine N-methyltransferase activity 0.863094487787088 bayes_pls_golite062009
transcription corepressor activity 0.782679886083722 bayes_pls_golite062009
transferase activity 0.385387347513497 bayes_pls_golite062009
catalytic activity 0.231344568578849 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [345-724]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RRTQWEDPRF ENENIAGPAV PYSRDYKRKV EYLRSRLPKP NSNSGKCDMV VHRDTLFEDS  60
   61 YRHIMDKKDY DLRNKLWIEF FGETGLDYGG VTREWFFLLS HQIFNPYYGL FEYSATDNYT 120
  121 LQINPHSEAC NPEHLSYFHF IGRIIGMAIY HGKLLDAFFI RPFYKMMLGK KITLFDMESV 180
  181 DNEYYNSLIY VKDNDPADLE LTFSLDDSIF GETQNIELIP NGANVPVTED NKEEYIEAVV 240
  241 PSNLLRLFDA NELELLMCGL QKIDVKDWKA NTIYKGGYGP SSQVVHNFWK CILSFDNEMR 300
  301 ARVLQFVSGT SRVPMNGFRE LYGSNGLQKF TIERWGSADM LPRAHTCFNR LDLPPYTTFK 360
  361 ELKSKLLTAI ENSEIFSGVD 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 106.0
Match: 2oniA
Description: No description for 2oniA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle