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View Structure Prediction Details

Protein: nas-8
Organism: Caenorhabditis elegans
Length: 403 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nas-8.

Description E-value Query
Range
Subject
Range
gi|187034732, gi... - gi|39593512|emb|CAE61804.1| Hypothetical protein CBG05771 [Caenorhabditis briggsae], gi|187034732|em...
gi|157756371 - gi|157756371|ref|XP_001670529.1| Hypothetical protein CBG05771 [Caenorhabditis briggsae AF16]
295.0 [0..1] [403..1]

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Predicted Domain #1
Region A:
Residues: [1-255]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRRNDLLNNK ITIFLSSLSL FVIIIPIYAA EKDLLPPSTS SETFLTDEDF LRPLNDDETF  60
   61 LTEKDFKNGE KLGEDHVPAG SILWKQVYKK GDIRGKAAWK LDPKNSESLR RNGVITGTRK 120
  121 WPNGRIPYVI SNQYNDRERA VLARSFQAYH DKTCVRFVPR TAVDNDYLYI GKIDGCYSDV 180
  181 GRAGGRQELS LDNGCLQYDT AIHELMHSVG FYHEHERWDR DEHITILWHN IDREAYDQFG 240
  241 KVDLAESSYY GQLYD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.39794
Match: 1slmA
Description: CRYSTAL STRUCTURE OF FIBROBLAST STROMELYSIN-1: THE C-TRUNCATED HUMAN PROENZYME
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.14857991858078 bayes_pls_golite062009
protein binding 0.430901196209551 bayes_pls_golite062009
signal transducer activity 0.430096231919693 bayes_pls_golite062009
molecular transducer activity 0.430096231919693 bayes_pls_golite062009
receptor binding 0.26922218944514 bayes_pls_golite062009
hydrolase activity 0.26760389419911 bayes_pls_golite062009
receptor activity 0.233571796352905 bayes_pls_golite062009
protein complex binding 0.171282539150091 bayes_pls_golite062009
peptidase activity 0.129618523753667 bayes_pls_golite062009
transmembrane receptor activity 0.0544613856966465 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [256-309]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YYSIMHYDSL AFSKNGFETM VAKQSEMTAV IGAAIDFSPI DILKMNLMYQ CSDV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.39794
Match: 1astA
Description: STRUCTURE OF ASTACIN AND IMPLICATIONS FOR ACTIVATION OF ASTACINS AND ZINC-LIGATION OF COLLAGENASES
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [310-403]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KLPPTVVGTT DKTIVPVPAP SVTVVEDDCR DRTNLCWRWI DRCKSFFFEQ IMKEFCSLSC  60
   61 GYCTPKALQT AKASPPNYSN TLLTKSSTSY LQHG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.39794
Match: 1nt0A
Description: Mannose-binding protein associated serine protease 2, MASP2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
receptor binding 2.52744864351239 bayes_pls_golite062009
ErbB-3 class receptor binding 2.14752073450101 bayes_pls_golite062009
binding 2.14092582858845 bayes_pls_golite062009
protein binding 1.87564165872234 bayes_pls_golite062009
ErbB-2 class receptor binding 1.86357079348628 bayes_pls_golite062009
growth factor activity 0.683947903955495 bayes_pls_golite062009
signal transducer activity 0.673391983395207 bayes_pls_golite062009
molecular transducer activity 0.673391983395207 bayes_pls_golite062009
transcription factor binding 0.5559753867952 bayes_pls_golite062009
epidermal growth factor receptor binding 0.49319143757878 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle