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View Structure Prediction Details

Protein: elt-2
Organism: Caenorhabditis elegans
Length: 433 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for elt-2.

Description E-value Query
Range
Subject
Range
RPB1_CAEBR - DNA-directed RNA polymerase II subunit RPB1 OS=Caenorhabditis briggsae GN=rpb-1 PE=3 SV=2
gi|157759005 - gi|157759005|ref|XP_001671846.1| Hypothetical protein CBG05355 [Caenorhabditis briggsae AF16]
158.0 [0..11] [327..1492]

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Predicted Domain #1
Region A:
Residues: [1-98]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDNNYNDNVN GWAEMEPSQP MGGLRLPTQN MDPPEQNNES QLSELPRMKI DNDYASPIER  60
   61 QSVITSGTNN YEPKVETVTS FFHTGIDYSN FGMLDQTT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [99-238]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQPFYPLYSG IPVNTLGTFS GYTNSIYDKP SLYDPSIPTI NIPSTYPTVA PTYECVKCSQ  60
   61 SCGAGMKAVN GGMMCVNCST PKTTYSPPVA YSTSLGQPPI LEIPSEQPTA KIAKQSSKKS 120
  121 SSSNRGSNGS ASRRQGLVCS 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [239-336]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NCNGTNTTLW RRNAEGDPVC NACGLYFKLH HIPRPTSMKK EGALQTRKRK SKSGDSSTPS  60
   61 TSRARERKFE RASSSTEKAQ RSSNRRAGSA KADRELST

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.30103
Match: 2gatA
Description: Erythroid transcription factor GATA-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 2.44628241003393 bayes_pls_golite062009
DNA binding 1.94519080035201 bayes_pls_golite062009
nucleic acid binding 1.85629109425119 bayes_pls_golite062009
protein binding 1.72653516930292 bayes_pls_golite062009
binding 1.62447538331668 bayes_pls_golite062009
transcription factor activity 1.37728257720121 bayes_pls_golite062009
transcription activator activity 1.10952708883226 bayes_pls_golite062009
sequence-specific DNA binding 0.78199243307321 bayes_pls_golite062009
catalytic activity 0.472235543748473 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.38848912999406 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [337-433]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AAVAAATATY VSHADLYPVS SAAVTLPDQT YSNYYQWNTA ATAGLMMVPN DQNYVYAATN  60
   61 YQTGLRPADN IQVHVMPVQD DETKAAARDL EAVDGDS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle