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Protein Overview: elt-2

General Information:
Name(s) found: elt-2 / CE31430 [WormBase]
Description(s) found:
Found 22 descriptions.
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  • WBGene00001250 locus:elt-2 Transcription factor elt-2 status:Confirmed UniProt:Q10655 protein_id:CAA90029.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 433 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][IEALink to PubMed article]
    Biological Process: regulation of epithelial cell differentiation [IMPLink to PubMed article]
    locomotory behavior [IMPLink to PubMed articleLink to PubMed article]
    nematode larval development [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    endoderm development [IMPLink to PubMed articleLink to PubMed article]
    digestion [IMPLink to PubMed article]
    regulation of transcription, DNA-dependent [IEALink to PubMed article]
    positive regulation of transcription from RNA polymerase II promoter [IDALink to PubMed article][IMPLink to PubMed articleLink to PubMed article]
    growth [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    reproduction [IMPLink to PubMed article]
    Molecular Function: transcription factor activity [IEALink to PubMed article][IMPLink to PubMed article]
    zinc ion binding [IEALink to PubMed article]
    RNA polymerase II transcription factor activity, enhancer binding [IDALink to PubMed articleLink to PubMed article]
    double-stranded DNA binding [IDALink to PubMed article]
    sequence-specific DNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDNNYNDNVN GWAEMEPSQP MGGLRLPTQN MDPPEQNNES QLSELPRMKI DNDYASPIER  60
   61 QSVITSGTNN YEPKVETVTS FFHTGIDYSN FGMLDQTTMQ PFYPLYSGIP VNTLGTFSGY 120
  121 TNSIYDKPSL YDPSIPTINI PSTYPTVAPT YECVKCSQSC GAGMKAVNGG MMCVNCSTPK 180
  181 TTYSPPVAYS TSLGQPPILE IPSEQPTAKI AKQSSKKSSS SNRGSNGSAS RRQGLVCSNC 240
  241 NGTNTTLWRR NAEGDPVCNA CGLYFKLHHI PRPTSMKKEG ALQTRKRKSK SGDSSTPSTS 300
  301 RARERKFERA SSSTEKAQRS SNRRAGSAKA DRELSTAAVA AATATYVSHA DLYPVSSAAV 360
  361 TLPDQTYSNY YQWNTAATAG LMMVPNDQNY VYAATNYQTG LRPADNIQVH VMPVQDDETK 420
  421 AAARDLEAVD GDS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..98] MSA 2.166996 View MSA. No confident structure predictions are available.
    2 View Details [99..238] deduced N/A No confident structure predictions are available.
    3 View Details [239..336] PSI-BLAST 9.30103 Erythroid transcription factor GATA-1
    4 View Details [337..433] MSA 4.171991 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • transcription regulator activity
    		•  2.44628241003393 bayes_pls_golite062009
  • DNA binding
    		•  1.94519080035201 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.85629109425119 bayes_pls_golite062009
  • protein binding
    		•  1.72653516930292 bayes_pls_golite062009
  • binding
    		•  1.62447538331668 bayes_pls_golite062009
  • transcription factor activity
    		•  1.37728257720121 bayes_pls_golite062009
  • transcription activator activity
    		•  1.10952708883226 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.78199243307321 bayes_pls_golite062009
  • catalytic activity
    		•  0.472235543748473 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.38848912999406 bayes_pls_golite062009
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle