| Protein: | nhr-120 |
| Organism: | Caenorhabditis elegans |
| Length: | 477 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nhr-120.
| Description | E-value | Query Range |
Subject Range |
|
|
306.0 | [0..5] | [471..21] |
|
Region A: Residues: [1-166] |
1 11 21 31 41 51
| | | | | |
1 MSSYWETMNC THLDKSNKLL HPSPPMWINR DSMNWVDGSL SSHSPMSSDS ISPLRSPAED 60
61 TNMVECSSNE LQPPAPIRKI RNVRKSDKHH CSVCGDRPTG YHYDVLSCNG CKTFFRRTII 120
121 NSRNFICTKG GNCQFTKDFR CACRACRFEK CVRVGMNPSA IQFPSS
|
| Detection Method: |  |
| Confidence: | 23.0 |
| Match: | 2hanB |
| Description: | No description for 2hanB was found. |
| Term | Confidence | Notes |
| transcription regulator activity | 4.00967542385368 | bayes_pls_golite062009 |
| DNA binding | 3.60745514727532 | bayes_pls_golite062009 |
| nucleic acid binding | 3.47256374293954 | bayes_pls_golite062009 |
| binding | 2.96409924710655 | bayes_pls_golite062009 |
| transcription activator activity | 2.9532663930699 | bayes_pls_golite062009 |
| transcription factor activity | 2.90769972671972 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 2.72967350701574 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 2.55186574506963 | bayes_pls_golite062009 |
| protein binding | 2.44501340584871 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.40923942043513 | bayes_pls_golite062009 |
| transcription repressor activity | 1.88834375049208 | bayes_pls_golite062009 |
| ligand-dependent nuclear receptor activity | 1.49515149729803 | bayes_pls_golite062009 |
| transcription factor binding | 1.38523780690867 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.26452462867497 | bayes_pls_golite062009 |
| transporter activity | 0.768214707487563 | bayes_pls_golite062009 |
| structural constituent of ribosome | 0.644659911825478 | bayes_pls_golite062009 |
| transcription coactivator activity | 0.61572149323953 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.58115018700114 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.50876329665586 | bayes_pls_golite062009 |
| structural molecule activity | 0.441960874303873 | bayes_pls_golite062009 |
| receptor activity | 0.230063209127305 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.187612502757984 | bayes_pls_golite062009 |
| catalytic activity | 0.101795606736461 | bayes_pls_golite062009 |
|
Region A: Residues: [167-477] |
1 11 21 31 41 51
| | | | | |
1 KNHNEADDMD SGDEDSNIQD DKSLALIPFV SAPLRETTIH TYRWVDDIFR REDAVLRHRI 60
61 PGTLPVEDDF CLGELLRKNI LIGGDCAIDR KPGTLYTNDP VRYWMVVDLL LIVEFAKTFE 120
121 SFRKLSEFDQ KCLISHIGGV LHVATQSFYS YFEAKSSTLT FPDGINAFER KMADVEKDDK 180
181 RRSRKVFLNY YAEMYNAPVN EFLKNKVTMT EYSFFKSISL FSPDNLEMSD AGRLIANEER 240
241 ERLTTLLRKY LVAEYGFKVG MNRFSLILMA ISTFVNYGEK RRDYISLMSL LKFDLANIGK 300
301 DIYLRKPIEM L
|
| Detection Method: | |
| Confidence: | 34.69897 |
| Match: | 1xdkB |
| Description: | Crystal Structure of the RARbeta/RXRalpha Ligand Binding Domain Heterodimer in Complex with 9-cis Retinoic Acid and a Fragment of the TRAP220 Coactivator |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 5.53061626347066 | bayes_pls_golite062009 |
| DNA binding | 4.92165988569962 | bayes_pls_golite062009 |
| nucleic acid binding | 4.78024150262074 | bayes_pls_golite062009 |
| transcription activator activity | 4.53302455129434 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 4.11614358606713 | bayes_pls_golite062009 |
| transcription factor activity | 4.0914094580319 | bayes_pls_golite062009 |
| ligand-dependent nuclear receptor activity | 3.89763470197726 | bayes_pls_golite062009 |
| binding | 3.85318710398432 | bayes_pls_golite062009 |
| transcription repressor activity | 3.83878598697109 | bayes_pls_golite062009 |
| protein binding | 3.21524787168952 | bayes_pls_golite062009 |
| transcription activator binding | 2.98235973123409 | bayes_pls_golite062009 |
| transcription factor binding | 2.68044489404568 | bayes_pls_golite062009 |
| receptor activity | 2.62895787183554 | bayes_pls_golite062009 |
| ecdysteroid hormone receptor activity | 2.46687081107237 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.38308182853979 | bayes_pls_golite062009 |
| steroid hormone receptor activity | 2.30195937604451 | bayes_pls_golite062009 |
| transcription coactivator activity | 2.27959329058894 | bayes_pls_golite062009 |
| signal transducer activity | 2.04709877069886 | bayes_pls_golite062009 |
| molecular transducer activity | 2.04709877069886 | bayes_pls_golite062009 |
| transcription cofactor activity | 1.73827483890179 | bayes_pls_golite062009 |
| nuclear hormone receptor binding | 1.60419100774741 | bayes_pls_golite062009 |
| retinoic acid receptor binding | 1.59968001933699 | bayes_pls_golite062009 |
| retinoid X receptor binding | 1.45560845709347 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.34794228300778 | bayes_pls_golite062009 |
| promoter binding | 1.28787959668198 | bayes_pls_golite062009 |
| palmitoyl-CoA hydrolase activity | 1.23181585568439 | bayes_pls_golite062009 |
| transcription corepressor activity | 0.995333369475571 | bayes_pls_golite062009 |
| hormone receptor binding | 0.95284349923679 | bayes_pls_golite062009 |
| retinoic acid receptor activity | 0.853869057774515 | bayes_pls_golite062009 |
| protein dimerization activity | 0.797229273848179 | bayes_pls_golite062009 |
| protein N-terminus binding | 0.57701453824007 | bayes_pls_golite062009 |
| thyroid hormone receptor activity | 0.49784404390361 | bayes_pls_golite062009 |
| structure-specific DNA binding | 0.47826452126899 | bayes_pls_golite062009 |
| lipid binding | 0.475303782949439 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.45265806678057 | bayes_pls_golite062009 |
| double-stranded DNA binding | 0.42652610679613 | bayes_pls_golite062009 |
| receptor binding | 0.418843034756825 | bayes_pls_golite062009 |
| androgen receptor activity | 0.399730816072004 | bayes_pls_golite062009 |
| ligand-regulated transcription factor activity | 0.202197503742221 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity, enhancer binding | 0.15737167800277 | bayes_pls_golite062009 |
| catalytic activity | 0.106902059021677 | bayes_pls_golite062009 |
| androgen binding | 0.0219623894804069 | bayes_pls_golite062009 |
