| Protein: | unc-63 |
| Organism: | Caenorhabditis elegans |
| Length: | 502 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for unc-63.
| Description | E-value | Query Range |
Subject Range |
|
|
414.0 | [0..1] | [502..1] |
|
Region A: Residues: [1-355] |
1 11 21 31 41 51
| | | | | |
1 MGPNDHGFAY ILIFLLLSPP THANRDANRL FEDLIADYNK LVRPVSENGE TLVVTFKLKL 60
61 SQLLDVHEKN QIMTTNVWLQ HSWMDYKLRW DPVEYGGVEV LYVPSDTIWL PDVVLYNNAD 120
121 GNYQVTIMTK AKLTYNGTVE WAPPAIYKSM CQIDVEFFPF DRQQCEMKFG SWTYGGLEVD 180
181 LQHRDKHLEK EIEEDVEGVD GPTKEIVWVV DRGIDLSDYY PSVEWDILNV PGKRHSKRYP 240
241 CCESPFIDIT YEIHLRRKTL FYTVNLIFPS VGISFLTALV FYLPSDGGEK ISLCISILIS 300
301 LTVFFLLLVE IIPSTSLVIP LIGKYLLFTM VLVTLSVVVT VVTLNVHYRS PTTHT
|
| Detection Method: |  |
| Confidence: | 77.0 |
| Match: | 2bg9A |
| Description: | Refined structure of the nicotinic acetylcholine receptor at 4A resolution. |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [356-502] |
1 11 21 31 41 51
| | | | | |
1 MPKWMKRLFV DFLPKYLLMT RPQPPGHHSK PNRKFDSRAS TFSIGVNHVL GQNSELLSPG 60
61 LNSNREESSF TLPRDNSPVR SAVESVAYIA DHLKNEEDDK QVIEDWKYIS VVMDRIFLIT 120
121 FTFACAFGTV VIIARAPSIY DNTPALA
|
| Detection Method: | |
| Confidence: | 42.0 |
| Match: | 1oedB |
| Description: | Acetylcholine receptor protein, beta chain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| acetylcholine binding | 13.9752632471881 | bayes_pls_golite062009 |
| acetylcholine receptor activity | 13.7533645836795 | bayes_pls_golite062009 |
| nicotinic acetylcholine-activated cation-selective channel activity | 13.1511875247796 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 11.9525876011069 | bayes_pls_golite062009 |
| extracellular ligand-gated ion channel activity | 11.7813202122163 | bayes_pls_golite062009 |
| excitatory extracellular ligand-gated ion channel activity | 11.7813202122163 | bayes_pls_golite062009 |
| cation channel activity | 11.7442066737514 | bayes_pls_golite062009 |
| ion channel activity | 11.1753684044644 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 11.0903806681397 | bayes_pls_golite062009 |
| channel activity | 11.0903806681397 | bayes_pls_golite062009 |
| gated channel activity | 11.0397691626728 | bayes_pls_golite062009 |
| substrate-specific channel activity | 10.9375522860542 | bayes_pls_golite062009 |
| ligand-gated ion channel activity | 9.34902726749692 | bayes_pls_golite062009 |
| ligand-gated channel activity | 9.34902726749692 | bayes_pls_golite062009 |
| amine binding | 9.11982124959723 | bayes_pls_golite062009 |
| chloride channel regulator activity | 9.10587892909341 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 7.22265353460749 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 7.19173677417054 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 6.7875346065164 | bayes_pls_golite062009 |
| transmembrane receptor activity | 5.4080353535498 | bayes_pls_golite062009 |
| receptor activity | 5.11329651194787 | bayes_pls_golite062009 |
| transporter activity | 5.11262082564788 | bayes_pls_golite062009 |
| transmembrane transporter activity | 5.03439798256257 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 4.91314874981447 | bayes_pls_golite062009 |
| neurotransmitter binding | 4.25797760547212 | bayes_pls_golite062009 |
| neurotransmitter receptor activity | 4.15404686068319 | bayes_pls_golite062009 |
| signal transducer activity | 4.12549692767753 | bayes_pls_golite062009 |
| molecular transducer activity | 4.12549692767753 | bayes_pls_golite062009 |
| adenylate cyclase binding | 3.30190657223613 | bayes_pls_golite062009 |
| binding | 2.4916526322278 | bayes_pls_golite062009 |
| beta-amyloid binding | 2.25766805801029 | bayes_pls_golite062009 |
| GABA-A receptor activity | 2.17863682705001 | bayes_pls_golite062009 |
| 1.68370717591127 | bayes_pls_golite062009 | |
| channel regulator activity | 1.66978990310631 | bayes_pls_golite062009 |
| protein binding | 1.45740893920165 | bayes_pls_golite062009 |
| G-protein coupled receptor activity | 1.42422063123689 | bayes_pls_golite062009 |
| serotonin binding | 1.33584589886834 | bayes_pls_golite062009 |
| serotonin-activated cation-selective channel activity | 1.31324203158511 | bayes_pls_golite062009 |
| toxin binding | 1.03329843925063 | bayes_pls_golite062009 |
| drug binding | 0.64715018605883 | bayes_pls_golite062009 |
| kinase binding | 0.365355763029699 | bayes_pls_golite062009 |
| protein kinase binding | 0.350601457777817 | bayes_pls_golite062009 |
